Tuberculosis can be cured with shorter treatments

Life

According to the study

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EFE. Almost half of the nearly ten million patients with active tuberculosis (TB) diagnosed every year can be cured with shorter treatments than those currently recommended, according to a study published in "Nature Medicine." A new analysis by the University of California in San Francisco (UCSF) suggests that the most accurate therapies could be more effective in treating tuberculosis (a bacterial infection), which kills 1.3 million people around the world per year. In the study – led by Marjorie Imperial, a graduate student in Pharmaceutical Sciences at the UCSF, he again analyzed the data obtained in three important trials that did not demonstrate the efficacy of four-month treatments to treat this infection that attacks the lungs. The UCSE emphasized that the reason for the failure of these previous trials is that all patients were treated in the same way, regardless of the new study, the research adds, when patients were retrospectively stratified in three categories of the disease status: minimum, moderate and severe, the treatment of four months with drugs was highly effective for the patient. % of patients with minimal illness. However, the four months were not effective for patients with moderate to severe TB. "Our study shows that a stratified medicine approach can be applied in a viable way to achieve a shorter treatment for many patients with TB," said Payam Nahid of the Faculty of Medicine of the aforementioned University of the United States. "A unique approach (treatment) leads to a low treatment for patients with a severe state of illness or excessive treatment for patients with less advanced disease because they receive medications that can cause damage," added Nahid. Tuberculosis has been treated with antibiotics Since the discovery of streptomycin in 1943, although the bacteria that cause the disease rapidly developed resistance to that antibiotic. In the seventies and eighties other rifampicin treatments were developed, but there was also resistance to that antibiotic, scientists recall. , which shows the danger of this situation given that tuberculosis currently kills more people in the world than the other infectious disease.
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