Home » World » Colombia’s new variant virus has invaded 26 countries and South Africa strains have 1 terrible common point | International | Sanli News Network SETN.COM

Colombia’s new variant virus has invaded 26 countries and South Africa strains have 1 terrible common point | International | Sanli News Network SETN.COM


Reporter Chen Yi/Report from Taipei

Just as the Indian variant virus (Delta) is raging around the world, other variants have emerged!The Colombian variant virus (B.1.621) has invaded at least 26 countries. Like the South African variant virus (Beta), B.1.621 has an E484K mutation in the spike protein, which has the characteristic of immune escape. This month, B.1.621 has been included in the list.BUTTER(Mutant strains to be noted).

▲Delta travels around the world, accounting for 69% of the total number of COVID-19 cases. (Picture/Retrieved from the online live broadcast of New Coronary Pneumonia Prevention Science)

National Taiwan University Public Health Doctor Lin Tingyu pointed out in a live broadcast of the new crown pneumonia epidemic prevention science yesterday (28) that the main international variant of the new crown virus is still Delta, and it is continuing to invade other countries. Last week, the global share was 52%. This week it has increased to 69%; the British variant (Alpha) is in second place, accounting for 14%; the Brazilian variant (Gamma) is in third place, accounting for 6%.

Lin Tingyu also mentioned the Colombian strain (B.1.621) that originated in South America. The number of related cases currently accounts for 10% of the infected population in South America and 2% of the world. In addition to the continued spread of the Colombian strain in South America, it also invaded 26 countries including the United States, the United Kingdom, and Spain.

Lin Tingyu said that the Colombian strain has a noteworthy feature, that is, its spiny protein has a mutation of E484K, which is the same as the well-known South African strain (Beta), and has immune escape characteristics, which may give us protection against existing vaccines. Raise doubts.

Recently, the number of cases of the Colombian strain has increased over time. Since July 20, it has been listed as a “variant of interest” (VOI) by the World Health Organization (WHO).

▲The Colombian variant virus also has a mutation of E484K, and there are doubts about immune escape. (Picture/Retrieved from the online live broadcast of New Coronary Pneumonia Prevention Science)

The World Health Organization and the Centers for Disease Control and Prevention of the United States divide the variant strains into three categories based on the degree of mutation of the new coronavirus on disease performance and prevention measures: “Variants of Interest” (VOI) and “High Concern” “Variants of Concern” (Variants of Concern, VOC) and “Variant of High Consequence” (VOHC).

“Pay attention to the variant strain” may affect the neutralization ability, disease transmission and severity and diagnostic tools due to the mutation site of the spike protein, such as B.1.525 (another variant in the UK), B.1.526 (2020) Variant strain found in New York in November 2015), P.2 (a variant strain found in Rio de Janeiro, Brazil) and B.1.621 (Colombian strain).

“Highly concerned mutant strains” have the characteristics of reducing antibody neutralization ability due to spike protein mutations, increasing virus transmission and disease severity, and may affect existing diagnostic tools and reduce vaccine protection. Such variants have become popular in certain regions, such as B.1.1.7 (British variant virus) that currently ravages Taiwan, B.1.617.2 (Indian variant virus), B.1.351 (South African variant virus), P.1 (Brazil variant virus), B.1.427 and B.1.429 (originally found in California, USA). Such variants will affect the epidemiology of the disease and may lead to amendments to drugs, vaccines and public health policies.

The most difficult “high-impact variants” have characteristics such as significantly reducing the protection of existing vaccines and increasing the severity of diseases, and will affect diagnostic tools, and are not effective in existing prevention and treatment methods.Fortunately, no mutant strains have been classified in this category.

Leave a Comment