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Mantle Cell Lymphoma Disease – Symptoms, Causes, Treatment

KOMPAS.com – Mantle cell lymphoma is a rare type of lymphoma that starts in your white blood cells.

Mantle cell lymphoma is considered non-Hodgkin’s lymphoma. This type of cancer is generally aggressive and difficult to diagnose until it eventually spreads throughout the body.

Also read: 11 Symptoms of Lymphoma Cancer to Watch Out for


Launch Medical News Today, experts do not yet know the exact cause of this disease.

However, about 85 percent of people with mantle cell lymphoma have genetic changes or mutations.

Mantle cell lymphoma is also associated with several other risk factors such as:

  • Elderly or aged 60 years and over
  • Male gender.


Based on Healthline, Symptoms of mantle cell lymphoma include:

  • Swollen lymph nodes
  • Fever or night sweats
  • Weight loss or loss of appetite
  • Nausea or vomiting
  • Fatigue
  • Discomfort due to enlarged tonsils, liver, or spleen
  • Gastrointestinal problems such as indigestion or stomach pain
  • Pressure or pain in the lower back.

Some people with mantle cell lymphoma have no obvious symptoms until the disease has spread throughout the body.


Your doctor can diagnose mantle cell lymphoma by performing the following tests and procedures:

Also read: Know the Symptoms and Stages of Development of Lymphoma Cancer

  • Tissue biopsy from the tumor and examine it
  • Blood test, check white blood cell count
  • Body scan, detects the location of cancer in the body.


The doctor will plan treatment depending on:

  • Age
  • Ability to perform daily activities
  • The level of leukocytes or white blood cells.

Based on Medical News Today, Treatment options for mantle cell lymphoma include:

  • Chemotherapy, is the main treatment to kill cancer cells
  • Stem cell transplant
  • Immunotherapy, using drugs and the body’s immune system to destroy cancer cells
  • Radiation therapy to further reduce cancer cells and increase the chances of successful treatment
  • Single drug treatment is an option for patients whose bodies are not healthy enough to handle the side effects of chemotherapy.


Reported from Healthline, People with mantle cell lymphoma are more likely to develop the following complications:

Also read: Lymphoma Cancer: Symptoms, Causes, and How to Overcome It

  • Low white, red, or platelet counts
  • A high white blood cell count that allows cancer to grow in arteries and veins
  • Gastrointestinal problems that can cause stomach problems, polyps, or stomach pain.

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This article is not intended for self-diagnosis. Please always consult a doctor to get the right examination and treatment.

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