Prediabrun, an unprecedented research initiative in the fight against diabetes in Reunion Island

The prevalence of type 2 diabetes continues to increase in France. Reunion is the French region most affected by this diabetes with twice as many people affected. Reunion diabetics are younger, more often women and have more frequent complications.

Prediabrun, has the ambition to put a brake on the increase in the number of diabetics in Réunion, by focusing its action on the phase that precedes diabetes.

A study focused on prediabetes in Réunion

Prediabrun is interested in subjects with prediabetes (or prediabetic subjects) in Reunion. Prediabetes is the stage that precedes diabetes. Prediabetic subjects are the most at risk of progressing to diabetes, but this transition is not automatic. This project aims to improve knowledge about prediabetes in order to slow down or even stop the transition to diabetes in these at-risk subjects.

Thus, this collaborative study aims to describe the characteristics of the prediabetic Reunionese and Reunionese included in the study and then to follow the evolution of their glycemia over time to identify all the socio-demographic, biological, medical and lifestyle factors. which have a role in the evolution towards diabetes or towards a return to normalcy, in order to offer the most appropriate care to reduce the passage from prediabetes to diabetes.

A study with regular medical follow-up by the attending physician

Prediabrun involves the active participation of treating physicians because they are the ones who refer patients to the study and continue to follow them, annually, as recommended by official recommendations.

The population-based study began in July 2019 and plans to recruit 200 volunteer general practitioners in charge of recruiting prediabetic subjects in their patients, with the aim of including 2,000 prediabetics and to assess their outcome over the following 5 years.

The study concerns patients aged 25 to 70 with prediabetes without a history of diabetes, except gestational diabetes.

Major spinoffs expected

The anonymized collection of health and lifestyle data on prediabetics will firstly improve scientific knowledge on prediabetes and secondly shed light on the risk factors for the onset of diabetes in these subjects.

The identification of such risk factors will contribute to improving the management of prediabetic subjects and the optimization of prevention campaigns at the local level.

* PREDIABRUN is supported by teams from the CHU de la Réunion in partnership with INSERM (National Institute of Health and Medical Research), the university department of general medicine, URML-OI (Regional Union of liberal doctors – Indian Ocean), the CGEOI (College of General Teachers of the Indian Ocean), the University of Reunion, the Health Insurance, the ARS and supported by the Reunion Region and the European fund.

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