Friday, 18 Jan 2019

Support of Directors of National Reference Centers to CNR of Borrelia

Paris, Saturday, April 21, 2018 – It was a pathology
almost unknown to the general public, with the exception of lovers of
walks in the forest that could be sensitized, see
face. Today, it is one of the diseases that make
regularly one of the news. This sudden notoriety
Most of the specialists who do not consider
not that there is scientifically convincing evidence for
justify the claims that Lyme disease
would be much more frequent than the estimates suggest
official languages ​​or that there are many forms
unrecognized chronicles. If the diagnostic tests know, at
like many others, some defects and risks of
false positives, most specialists do not judge more
that they have to consider them as totally tools
ineffective ones having made the bed of a hidden epidemic.

Yet, such representations are today so
well anchored in the population that they are now defended
by many media but also by several representatives

Justice has been seized several times
times. This situation weakens the work that attempts to
lead the experts on infectious diseases, which are the subject
unfounded and violent attacks more and more frequent.
Also, even if their voices often remain difficult
heard, doctors and scientists decided to unite to say
their support for those who are unjustly tormented. The directors
Many national reference centers address this
at JIM a forum intended to remind the seriousness of the CNR dedicated to
borreliosis which is the subject of accusations without proof, incessant
and sometimes insane.

They here assure their fellow members of this CNR support without

By the directors of different CNR *

National Reference Centers for the fight against
communicable diseases are laboratories appointed by order of the
Ministry of Health, on the proposal of the director
General de Santé Publique France, the national health agency
Public. These laboratories recognized for their excellence
scientific and ability to provide consultancy missions,
expertise, contribution to monitoring and alerting, are
CNR labels following a call for applications procedure and
an evaluation of the files carried out by the experts
independent from the NRC Committee, placed with the Director General
Public Health France. The list of these laboratories is
available on the website of Public Health France ( ).

A scientific, measured and professional approach

Borreliosis, of which Lyme disease is the main
recognized event, are represented in the CNR network
by Prof. Benoit Jaulhac’s laboratory in Strasbourg.

The CNR of Borreliosis has for several years been the subject of a
highly publicized campaign that combines disparagement,
accusations of conflict of interest, endangering life
others and direct personal threats to his
Director and all the people who defend positions
measured on the role of Borrelia in human pathology beyond
events recognized by the medical community. A debate
legitimate scientist on this issue exists and must be
continue. But this debate seems today notoriously contaminated
by considerations that go beyond the scope of the rational and the
evidence-based medicine, which alone should
to guide medical practices in the interests of patients.
Directors and members of the different NRCs who signed this
letter wish to publicly demonstrate their support for the CNR
Borrelia in his scientific, measured and professional approach
of the question. We believe that the best service that can be
to patients is the rigor of the medical approach
evidence-based, even if this approach imposes a higher tempo
slow than that legitimately hoped by all those who suffer.

Test evaluation: a classic CNR mission

With respect to the issues of interest, we
recalls that, as part of the expertise mission, the CNRs must
participate in the development, optimization, validation,
dissemination and recommendations concerning
medical biology (diagnostic, identification and / or
typing) relating to the pathogens for which they are responsible “.
As such, the kits and diagnostic reagents of the different
suppliers are evaluated by the NRCs. This evaluation work
constitute no obvious link of interest when the staff
CNR receives no direct remuneration from the industrial
concerned and that this manufacturer has no power of influence over
the results of this evaluation exercised in

* Signatories

Francois Vandenesch, Dir. CNR of Staphylococci
Jacques Izopet, Dir. CNR Transmission Hepatitis Virus
enteric (hepatitis A and E)
Philippe Lehours, Dir. CNR Campylobacter and Helicobacter
Sylvain Baize, Dir. CNR Viral haemorrhagic fevers
Sylvain Brisse, Dir. CNR Whooping Cough and Other Bordetelloses
Patrick Plésiat, Dir. CNR Resistance to antibiotics
Jean-Philippe Lavigne, Dir. CNR LABORATORY EXPERT Brucella
Vincent Jarlier, Dir. CNR of Mycobacteria and resistance
Emmanuelle Varon, Dir. CNR Pneumococci
Mathieu Picardeau, Dir. CNR Leptospirosis
Jean-Luc Pretet, Dir. CNR Papillomavirus
Max Maurin, Dir. CNR Laboratory expert Francisella
Cécile Bebear, Dir. CNR Sexually Transmitted Infections
(IST) Bacterial
Jean-Marc Reynes, Dir. CNR Hantavirus
Laurence Millon, Dir. CNR Echinococcosis
Marc Lecuit, Dir. CNR Listeria
Christelle Mazuet, Dir. CNR Anaerobic bacteria and
Astrid Vabret, Dir. CNR Measles, rubella and measles viruses
Claire Poyart, Dir. CNR of Streptococci
François-Xavier Weill, Dir. CNR Escherichia coli, shigella,
Pierre-Edouard Fournier, Dir. CNR Rickettsia, Coxiella and
Frederic Laurent, Dir. Adjt. CNR of Staphylococci
Anne Tristan, Dir. Adjt. CNR of Staphylococci
Marie-Laure Quilici, Dir. CNR Vibrios and cholera
Françoise Dromer, Dir. CNR Invasive and Antifungal Mycoses
Olivier Lortholary, Dir. Adjt. CNR Invasive Mycoses and
Stéphane Brittany, Dir. Adjt, CNR Invasive Mycoses and
Sophie Alain, Dir. CNR Herpesvirus
David Boutolleau, Dir. CNR Associated Laboratory Herpesvirus
Syria Laperche, Dir. CNR Infectious Transfusion Risks
David O’Callaghan, Dir. CNR Brucella Expert Laboratory
Sophie Jarraud, Dir. CNR Legionella
Gerard Lina, Dir. Adjt. CNR Legionella
Isabelle Leparc-Goffart, Dir. CNR arbovirus
Marie-Laure Chaix-Baudier, Dir. CNR Immunodeficiency Virus
Human (HIV)
Francis Barin, Dir. CNR Associated Laboratory Virus
Human Immunodeficiency (HIV)
Isabelle Villena, Dir. CNR Toxoplasmosis
Patrick Bastien, Dir. CNR Associated Laboratory Toxoplasmosis
Ermanno Candolfi, Dir. NRC Associate Laboratory
Marie-Laure Dardé, Dir. NRC Associate Laboratory
Frederic Barbut, Dir. CNR Associated Laboratory Bacteria
anaerobes and botulism Francis Megraud, Dir. Adjt. CNR
Campylobacter and Helicobacter

The headings are from the editorial staff.

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