Deaths from coronavirus in Brazil reach 359 and confirmed cases rise to 9,056

Sixty people died in Brazil in the last 24 hours from thecoronavirus, which brings the total number of deaths from the pandemic to 359, while in the same period 1,146 infections were verified, which added to the previous ones gathered 9,056, the government of President Jair Bolsonaro reported today.

The figures were released this afternoon in the usual report by the Ministry of Health, which considered them as “a natural growth” and still “smooth” of the curve of incidence of the virus, which should accelerate in the coming weeks in this country of 210 million inhabitants.

The Health Minister, Luiz Henrique Mandetta, again recommended as measures to stop the virus, measures to restrict social life that are criticized by Bolsonaro himself.

“Again, the recommendation to reduce activities and all social dynamics. I do not say restriction or quarantine. It is to minimize contact” between people, especially due to the enormous difficulty of acquiring medical equipment, which is mostly produced in China, Mandetta said at a press conference, according to the EFE news agency.

The minister cited the case of a shipment of 680 respirators that two states in the northeast region of the country had acquired from a Chinese company and was detained after the manufacturer decided, without explanation, to cancel the contract.

“We must have redoubled attention, because until now the virus is more present in the middle and upper classes, but it has not reached with full force in the favelas and working class neighborhoods,” warned Mandetta.

In Brazil “we are just beginning autumn and winter (which will begin in June) will be our worst nightmare,” said the minister regarding the horizon for the coming months.

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COVID-19: Pharmaceutical company announces that medicine for the disease is ready

The Spanish pharmaceutical company PharmaMar has reported that all the results obtained through in vitro examinations for its clinical study of the drug Aplidin (possible drug for the coronavirus) have been positive.

According to the research group, the potency that Aplidin has shown in its effectiveness is a nanomolar order. So it is possible that this will help reverse the symptoms that the coronavirus.

Medication use

This type of medication is frequently used for the treatment of Hematological Cancer, being approved in several countries, such as Australia, Taiwan, New Zealand and South Korea.

Most of the studies carried out for this medicine have been carried out at the National Center for Biotechnology of the Superior Center for Scientific Research. There, several experts have devoted themselves to seeing the effectiveness of the medicine against the disease.

Among the results obtained, it has been possible to verify a hypothesis in which it is proposed that the therapeutic target of this antitumor drug called Aplidin. This has had a key response for the multiplication and spread of the virus itself.

The protein that causes this situation is known as EF1A, essential for the virus to expand within the human body.

Function

This process is known as nucleoprotein, where the virus manages to become visible and also manages to reproduce, finally spreading through the cells of the body. The role it would fulfill Aplidin it would be to hijack the virus, forming a resistance (stable complex) that would cause the virus to be unable to spread and be viable in the body.

Human testing?

Thanks to these results, the PharmaMar pharmacist will carry out all the subsequent steps in order to contact the health authorities. Thus begin to carry out tests on human patients infected with the disease, to check how they behave.

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