scientists from Brazil claimed to have a medicine capable of stopping COVID-19

Experts from the Fiocruz Development Center analyzed Atazanavir, a drug used against HIV that could be effective against coronavirus.

A group of Brazilian scientists from the center Fiocruz could have found a medicine against coronavirus. This is Atazanavir, a remedy used to treat HIV-infected patients.

This medicine has an anti-inflammatory function, since it helps to reduce the inflammatory process in the lungs. According to recent research, the drug may inhibit viral replication of SARS-CoV-2.

Recall that this center is located in Brazil and is currently one of the largest medical research centers in Latin America, working directly with the government of that country.

Coronavirus: Brazilian scientists claimed to have a medicine capable of stopping COVID-19

Coronavirus and Brazil

As a result of the investigations and monitoring that has been done to the virus, the experts noticed several characteristics. One of the first is that Atazanavir is able to stop the multiplication of the coronavirus in the body.

This would be achieved thanks to its anti-inflammatory capacity, which is why it is used to face AIDS.

As Atazanavir was exposed to the SARS-CoV-2 spike protein, it showed a positive reaction. According to a statement delivered by the Institution, the drug managed to “reduce the proteins that are linked to the inflammatory process in the lungs.”

Coronavirus: Brazilian scientists claimed to have a medicine capable of stopping COVID-19

The direct intervention of the drug can affect the reduction of the serious clinical picture generated by the coronavirus. Although the investigation is still preliminary, it may be a door for a possible drug to face the pandemic.

In the words of Thiago Moreno, Fiocruz researcher and one of the project coordinators, “Testing for drugs already approved for other uses is the fastest strategy that science can offer to combat COVID-19.”. For his part, the expert also emphasized that social distancing is also another essential measure.

For their part, experts will continue studies to analyze the long-term effectiveness of the drug. It is hoped that the utility may increase with the combined use of Ritonavir and Atazanavir, which are targeted medicines to treat AIDS.

Coronavirus: Brazilian scientists claimed to have a medicine capable of stopping COVID-19

Possible medication for the disease

Researchers at the Center for Technological Development in Health believe they have found a more effective mediation than Chloroquine. According to them, Atazanavir causes better bioavailability in the respiratory tract. This situation can be transcendental in the fight against SARS-CoV-2 and its reproduction.

This means that the drug manages to occupy the cleft of the active substrate during molecular analyzes. With this, it could block the advance of the virus.

Coronavirus: Brazilian scientists claimed to have a medicine capable of stopping COVID-19

The researchers will continue to test the reaction through various cell types using in vitro assays. Those that will be dealt with will be the following:

  • Lung cell
  • Human epithelial cell
  • Human primary monocytes

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There are 1,688 positive cases in Mexico – Noticieros Televisa

Health authorities reported that until the cut of today, April 3, 2020, the death toll from coronavirus in Mexico rose to 60, while the confirmed cases rose to 688 thousand.

In today’s press conference, from the National Palace, José Luis Alomía, director of Epidemiology of the Ministry of Health, pointed out that in the last hours there were 10 more deaths than yesterday and in terms of positive cases there are 178 more.

As for suspicious cases, the figure stands at 5,398.

He called on the population over 60 to stay home to prevent them from getting coronavirus.

With information from Televisa News.

RMT

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US CDC Admits to Misdiagnosing Coronavirus Patients

The Center for Disease Control and Prevention (CDC) has admitted to misdiagnosing some patients with # COVID_19, this according to a tweet from Lijian Zhao, a Chinese politician and current deputy director of the Information Department at the Ministry of Foreign Affairs. .

According to Zhao, several people were diagnosed with the flu instead of COVID-19 during the 2019 flu season.

Given this, Zhao encouraged the authorities to get patient 0 since the COVID-19 virus has been around since September of last year.

According to CDC statisticsBetween October 2019 and February 2020, the flu affected some 34 million people, of whom an estimated 12,000 died. On the other hand, the coronavirus has infected more than 300,000 and a total of 14,611 people have died. The World Health Organization (WHO) It has identified more than 150 with cases of coronavirus.

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Coronavirus: Only six leagues are active in all of America

With the suspensions of Mexico, Brazil and Ecuador, there are fewer active soccer leagues in America, despite the coronavirus pandemic that killed more than 6,000 people worldwide.

This weekend, Liga MX, the Brazilian Soccer Confederation – the governing body of tournaments in Brazil – and Liga Pro in Ecuador decided to stop as a form of virus containment.

In all three cases, the pressure from soccer players took effect, especially in South American countries, annoyed at having to put their health at risk.

Although there are still six countries with active soccer on the continent, it is expected that more leagues will continue to close this week, given the advance of the deadly virus.

Here are the six countries that still have active tournaments on the continent.

Concacaf

Costa Rica: Deportivo Saprissa is leader with 33 points, after tying one with Pérez Zeledón on date 15.

Schedule 16 is scheduled for next week. The Costa Rican is a twelve club tournament.

Guatemala: Communications continues to command the National League by defeating Municipal 3-0 on Sunday on the 13th.

Matchday 14 would take place next weekend. The Guatemalan championship is twelve teams.

Nicaragua: Diriangén assumed the top of the Nicaraguan first division, after defeating Real Estelí 2-0: he reached 17 points, after Managua’s draw to one against Municipal Jalapa.

The tournament is ten teams and the date nine would be played this Wednesday.

Conmebol

Argentina: In the Argentine Soccer Association there is a debate on whether to play behind closed doors or to suspend the Super League Cup, the current competition in dispute.

The powerful River Plate did not want to play this weekend to prevent its footballers from suffering the effects of the coronavirus: the rest of the clubs did not support him.

The President of the Republic, Alberto Fernández, suggested that the teams take action behind closed doors and that the channels open their broadcasts to the public.

Bolivia: The Strongest is the leader of the Bolivian championship, after beating Aurora 2-1 on matchday 12.

The Tigers have 21 points, with the same amount as Always Ready but with a better goal difference.

Date 13 is scheduled for next weekend. The league has 14 teams.

Chile: Everything continues in the Chilean first division, with Universidad Católica at the head.

The Crusaders defeated Cobresal 1-0 on Saturday, reaching 19 points. This Monday follows date eight, and the ninth begins on Thursday.

The austral tournament has 18 clubs.

Recall that the parties that were suspended over the weekend –Palestino vs. Universidad de Chile and Colo Colo vs. Santiago Wanderers- were motivated by the social protests that still shake the nation.

Tournaments suspended by the coronavirus in America

Until now, in the Concacaf: Panama, El Salvador, United States, Canada, Mexico.

In the Conmebol: Peru, Paraguay, Uruguay, Colombia, Venezuela, Brazil, Ecuador.

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COVID-19: Pharmaceutical company announces that medicine for the disease is ready

The Spanish pharmaceutical company PharmaMar has reported that all the results obtained through in vitro examinations for its clinical study of the drug Aplidin (possible drug for the coronavirus) have been positive.

According to the research group, the potency that Aplidin has shown in its effectiveness is a nanomolar order. So it is possible that this will help reverse the symptoms that the coronavirus.

Medication use

This type of medication is frequently used for the treatment of Hematological Cancer, being approved in several countries, such as Australia, Taiwan, New Zealand and South Korea.

Most of the studies carried out for this medicine have been carried out at the National Center for Biotechnology of the Superior Center for Scientific Research. There, several experts have devoted themselves to seeing the effectiveness of the medicine against the disease.

Among the results obtained, it has been possible to verify a hypothesis in which it is proposed that the therapeutic target of this antitumor drug called Aplidin. This has had a key response for the multiplication and spread of the virus itself.

The protein that causes this situation is known as EF1A, essential for the virus to expand within the human body.

Function

This process is known as nucleoprotein, where the virus manages to become visible and also manages to reproduce, finally spreading through the cells of the body. The role it would fulfill Aplidin it would be to hijack the virus, forming a resistance (stable complex) that would cause the virus to be unable to spread and be viable in the body.

Human testing?

Thanks to these results, the PharmaMar pharmacist will carry out all the subsequent steps in order to contact the health authorities. Thus begin to carry out tests on human patients infected with the disease, to check how they behave.

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