neffy®, adrenaline nasal spray, now approved to treat anaphylaxis in Australia – News Hub

by Chief Editor

A New Era in Anaphylaxis Treatment: Needle-Free Adrenaline Now Available in Australia

Melbourne, February 16, 2026 – Australians at risk of life-threatening allergic reactions now have a new weapon in their arsenal. neffy® adrenaline (epinephrine) nasal spray has been approved for use in Australia for the emergency treatment of anaphylaxis in adults and children aged four years and over weighing 15kg or more.1 This marks the first time in over 30 years that a new method of administering adrenaline has been approved in the country.

The Rising Tide of Anaphylaxis in Australia

Anaphylaxis, a severe and potentially fatal allergic reaction, is a growing concern in Australia. Between 2015 and 2020, Australian public hospitals saw a 51% increase in emergency department presentations and a 35% increase in hospitalisations due to anaphylaxis.6,7 Common triggers include food allergies, medications, and insect stings.3 Symptoms can range from difficulty breathing and swelling of the tongue to dizziness, and collapse.3

How Does neffy Work?

Adrenaline is the first-line treatment for anaphylaxis, working by rapidly reversing the symptoms by reducing throat swelling, opening airways, and stabilizing heart function and blood pressure.3 Traditionally, adrenaline has been administered via injection. neffy offers a needle-free alternative, delivering the medication through a nasal spray. This can be particularly beneficial for individuals who are anxious about injections or have difficulty self-administering them.

Expert Perspectives on the New Treatment

Professor Connie Katelaris AM, a leading NSW allergist, welcomes the arrival of neffy. “The approval of neffy is very welcome as it gives patients and their doctors a nasal administration option and choice in managing their condition,” she stated. Maria Said AM, Health Strategy and Advocacy Manager at Allergy & Anaphylaxis Australia, emphasized the impact on daily life: “Having a new treatment option which does not require injection will offer people at risk of anaphylaxis, and their treating doctor, the ability to choose an adrenaline device that best suits their needs.”

Future Trends in Anaphylaxis Management

The introduction of neffy signals a broader shift towards patient-centered and more accessible anaphylaxis management. Several trends are likely to shape the future of this field:

  • Increased Focus on Prevention: Research into identifying individuals at high risk of developing allergies and implementing preventative strategies, such as early introduction of allergenic foods, will become increasingly important.
  • Personalized Medicine: Tailoring treatment plans based on individual allergy profiles and risk factors could optimize outcomes.
  • Technological Advancements: Smart devices and mobile apps could help individuals track their allergies, monitor symptoms, and receive timely alerts.
  • Improved Education and Awareness: Continued efforts to educate the public, healthcare professionals, and schools about anaphylaxis recognition and management are crucial.
  • Expanded Access to Treatments: CSL Seqirus is hoping to expand access to neffy through inclusion on the Pharmaceutical Benefits Scheme (PBS), with a decision expected in March 2026.

What Does This Mean for Australians?

The availability of neffy provides a valuable new option for individuals at risk of anaphylaxis. It empowers them to manage their condition with greater confidence and convenience. Healthcare organizations are already updating their resources and anaphylaxis education to incorporate this new treatment.

Did you recognize?

Australia has one of the highest documented rates of anaphylaxis hospital admissions in the developed world.5

Frequently Asked Questions (FAQ)

  • What is anaphylaxis? Anaphylaxis is a severe, potentially life-threatening allergic reaction that affects multiple body systems.3
  • How does neffy differ from traditional adrenaline injections? neffy is a needle-free nasal spray, offering an alternative administration method.
  • Is neffy available on the PBS? Currently, neffy is not listed on the Pharmaceutical Benefits Scheme. A decision on PBS listing is expected in March 2026.
  • What are the common side effects of neffy? Common side effects include headache, nasal discomfort, throat irritation, and feeling jittery.1

Pro Tip: Always carry your adrenaline auto-injector (or neffy) with you, and ensure those around you know how to use it in an emergency.

For more information about neffy and anaphylaxis management, visit cslseqirus.com.au/products or consult with your healthcare provider.

Disclaimer: This information is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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