Antigen

Liver Fibrosis Severity Predicts HBeAg-Positive CHB Treatment Response

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Baseline Liver Fibrosis Severity Predicts Hepatitis B Treatment Response Baseline liver fibrosis severity acts as a key independent factor in predicting treatment response to pegylated interferon-alpha combined with nucleos(t)ide analogs in patients with hepatitis B e antigen-positive chronic hepatitis B, according to a study published in the Journal of Clinical and Translational Hepatology. Researchers at … Read more

City of Hope Develops Modular Plug-and-Play CAR T Therapy for Tumors

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City of Hope investigators have formulated an innovative plug-and-play technique that incorporates engineered molecules into chimeric antigen receptor (CAR) T cells post-treatment, based on findings shared this month in Cancer Immunology Research, an American Association for Cancer Research journal. The preclinical study offers a flexible approach to help CAR T cells keep pace with mutating … Read more

Scorpion Venom for Liver Disease: Can It Inspire New Treatments?

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Scorpion venom peptides are emerging as targeted drug candidates for inflammatory pathways and hepatitis viruses, according to a recent review published in the journal iLIVER. Researchers summarized how these molecules, sourced from over 2,700 documented scorpion species, target receptor proteins and voltage-gated ion channels to treat chronic inflammatory and hepatic disorders without the broad toxicity … Read more

Nanomaterials: A New Frontier in Cancer Immunotherapy

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Researchers at Nankai University have developed a framework for integrated nanomaterials designed to overcome the physiological and immune-based barriers that frequently limit the effectiveness of cancer immunotherapy. Published April 24, 2026, in the Chinese Journal of Polymer Science, the study outlines how coordinated nanomaterial design can improve drug delivery, antigen presentation, and tumor microenvironment reprogramming … Read more

New Breast Cancer Classification Predicts Immunotherapy Success

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Researchers from the Department of Breast Surgery at Fudan University Shanghai Cancer Center and the Department of Oncology at Shanghai Medical College, Fudan University have developed a new classification system for breast cancer based on the cancer-immunity cycle (CIC). Published in Cancer Biology & Medicine in 2026, this framework uses a “CIC score” to categorize … Read more

Universal Sarbecovirus Vaccine Shows Promise in First Human Trial

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The End of “Reactive” Medicine: How AI is Ending the Pandemic Chase For decades, humanity has played a high-stakes game of cat-and-mouse with viruses. When a new pathogen emerges, scientists rush to sequence it, manufacture a targeted vaccine, and scramble to distribute it—often just as the virus begins to mutate into something new. We see … Read more

PSMA PET: Detecting High-Risk Prostate Cancer Bone Metastases

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The Invisible Threat: Why Standard Scans Are Failing Prostate Cancer Patients Imagine receiving a report from your doctor stating that your bone scan is perfectly clear. You breathe a sigh of relief, thinking the cancer is contained. But beneath the surface, a silent progression is already underway. This is the harrowing reality for a significant … Read more

Predictive Model Optimizes PSMA Therapy for Prostate Cancer

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Revolutionizing Prostate Cancer Care: The Future of Personalized Radiotherapy For patients battling metastatic castration-resistant prostate cancer (mCRPC), the path to effective treatment is often complex. A breakthrough in machine learning is now offering a glimpse into a more precise future, where clinicians can estimate radiation doses to tumors and healthy organs before therapy even begins. … Read more

Cytokine-armored CAR-T cell therapy successfully attacks aggressive brain tumors in mice

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Beyond Blood Cancers: The New Frontier of Solid Tumor Therapy For years, CAR-T cell therapy has been hailed as a miracle for certain blood cancers, but solid tumors—particularly aggressive brain cancers like glioblastoma—have remained stubbornly resistant. The challenge isn’t just the cancer itself, but the “shield” these tumors build around themselves to hide from the … Read more

New mRNA vaccine strategy dramatically amplifies cancer-fighting T cells

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The New Frontier of Immunotherapy: Reprogramming the Body to Fight Cancer For decades, vaccines have relied on adjuvants—substances added to a vaccine to create a stronger immune response. However, traditional adjuvants often provide only short-lived stimulation. A groundbreaking shift is now occurring, moving away from external triggers toward “reprogramming” the immune system from the inside … Read more

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