Breast Cancer

Astrin Aims for Mainstream with Certitude Breast Cancer Test

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Astrin Biosciences is expanding physician outreach and preparing a direct-to-consumer launch for Certitude, a proteomic-based breast cancer diagnostic test that leverages mass spectrometry and machine learning. According to the company, the test identifies high-risk patients and detects early-stage malignancies from a small plasma sample. How Proteomics and AI Outperform Traditional DNA Liquid Biopsies in Early … Read more

Viagra Ingredient Stops Cancer Spread in World First Study

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< div> According to peer-reviewed research published in July in Cancer Research, sildenafil—the active ingredient in Viagra—disrupts cancer cells’ cholesterol supply to stop the spread of metastases. Researchers at the Weizmann Institute of Science, alongside teams from the US National Cancer Institute and Clalit Health Services, found that the drug targets the protein transporting essential … Read more

Why Cancer Patients Must Avoid Unproven ‘Natural’ Cures

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According to medical experts, lifestyle interventions such as diet modifications, stress reduction, and natural remedies cannot cure cancer or replace evidence-based treatments like chemotherapy and surgery. While healthy habits support patient well-being, oncologists warn that delaying proven medical care to pursue alternative therapies allows the disease to progress and reduces survival chances. The Limits of … Read more

Heart Risk Calculators Predict Cancer Risk, Study Finds

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Cardiovascular risk calculators currently used by doctors to predict heart attacks and strokes can also estimate a patient’s risk of developing certain cancers, according to a study published in the European Journal of Cancer. Researchers at University College London (UCL) found that tools like QRISK3—widely used in the UK—performed with comparable accuracy to specialized cancer … Read more

Bile acid buildup linked to aggressive breast cancer progression

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Research from the University of Virginia (UVA) Comprehensive Cancer Center indicates that a buildup of bile acids, triggered by an unhealthy gut microbiome, can drive hormone receptor-positive (HR+) breast cancer to metastasize to other organs, particularly the lungs. According to Melanie Rutkowski, PhD, this mechanism suggests that FDA-approved bile acid sequestrants or microbiome replenishment could … Read more

Obesity Linked to 19 Cancers: Why Excess Weight Is a Major Health Risk

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A comprehensive review of over 1.5 million cancer cases, published in Nature Metabolism, has identified a link between obesity and an increased risk of 19 different types of cancer. The study provides evidence that excess body fat acts as an active biological driver for malignancies, including leukaemia, non-Hodgkin lymphoma, bladder cancer, and glioma. Dr. Saneya … Read more

New Breast Cancer Classification Predicts Immunotherapy Success

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Researchers from the Department of Breast Surgery at Fudan University Shanghai Cancer Center and the Department of Oncology at Shanghai Medical College, Fudan University have developed a new classification system for breast cancer based on the cancer-immunity cycle (CIC). Published in Cancer Biology & Medicine in 2026, this framework uses a “CIC score” to categorize … Read more

How Obesity Drives Invasive Breast Cancer: Key Molecular Pathways

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Obesity is associated with a distinct molecular program in breast tissue that drives the transition from premalignant lesions to invasive cancer, according to a study published in The American Journal of Pathology. Researchers found that tumors in obese patients rely on stress-adaptive pathways and microenvironment remodeling rather than classical invasive pathways, suggesting that metabolic health … Read more

Gut Microbes Linked to Estrogen-Driven Cancers

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Scientists are increasingly viewing gut microbes as active participants in hormone-driven cancers, moving beyond the traditional “estrobolome” model to define a bidirectional endocrine-microbiome axis. According to a review published in the journal npj Biofilms and Microbiomes, researchers are investigating how these microbial communities influence the metabolism of estrogen and contribute to the development of breast … Read more

Unlocking the Secrets of a Key Cancer and Neurological Disease Protein

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How Did Researchers Solve a 40-Year-Old Mystery? After four decades of research, Mayo Clinic scientists have unveiled the molecular structure of protein kinase C beta (PKCβ), a protein linked to cancer and neurological diseases. The breakthrough, published in Nature Communications, provides the first detailed view of how PKCβ functions and how the breast cancer drug … Read more

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