RNA-binding proteins (RBPs) play a critical role in every phase of RNA metabolism, including the processing, modification, translation, and decay of RNA. These proteins are also essential for the function of non-coding RNAs, shaping cell identity and contributing to the development of various diseases. Systematic efforts to explore the RNA interactome have expanded the known … Read more
Antimalarial resistance in Uganda is shifting as researchers identify a strong selective sweep on chromosome 7 centered on px1, threatening artemisinin-based combination therapies that remain critical for global disease control. Whole-genome sequencing of 157 Plasmodium falciparum samples by Niaré et al. revealed this emerging genetic signature alongside known signals at the k13 locus on chromosome … Read more
Circulating tumor cells in multiple myeloma serve as a compound biomarker for bone marrow high-risk genomic alterations and tumor load, according to a 2026 study published in Blood by Fokkema and colleagues. This blood-based marker helps clinicians evaluate aggressive disease features without always relying solely on repeated bone marrow biopsies. Genomic Complexity and Circulating Tumor … Read more
According to research published in the journal Nature, a new search platform called Malva enables scientists to search RNA sequences across millions of individual cells in seconds without downloading enormous raw datasets or mapping them against a reference genome. Developed by creators including Nikolaus Rajewsky, Daniel León-Periñán, and Nikos Karaiskos, the system has indexed more … Read more
Popular over-the-counter vitamin B3 supplements—including nicotinamide mononucleotide, nicotinamide riboside, and nicotinamide—can help pancreatic cancer cells survive chemotherapy, according to a study published in Cancer Letters by researchers at the Case Western Reserve University School of Medicine. While these compounds are widely taken by Americans to boost energy and support healthy aging, the new findings show … Read more
< div> According to peer-reviewed research published in July in Cancer Research, sildenafil—the active ingredient in Viagra—disrupts cancer cells’ cholesterol supply to stop the spread of metastases. Researchers at the Weizmann Institute of Science, alongside teams from the US National Cancer Institute and Clalit Health Services, found that the drug targets the protein transporting essential … Read more
A new blood test, Stockholm3, detected 90% of aggressive prostate cancer cases in clinical trials, outperforming the traditional prostate-specific antigen (PSA) test, which identified 74%. According to a study published in the Annals of Internal Medicine, the test could improve early detection of curable disease while reducing unnecessary biopsies and MRIs for men aged 50 … Read more
Cancer Research UK is increasing its annual investment in the Manchester Biomarker Centre from £11m to £17m to accelerate the development of personalized cancer treatments. The facility, located within the University of Manchester’s Paterson building, will use the funding to integrate artificial intelligence, data science, and immunology into its clinical research, while recruiting 100 additional … Read more
Beyond the Pandemic: The New Frontier of mRNA Medicine The global success of COVID-19 vaccines was merely the opening act. While mRNA technology made household names of companies like Moderna and Pfizer-BioNTech, the true revolution is only just beginning. We are moving from a world where mRNA is synonymous with “vaccine” to one where it … Read more
The Heart’s Secret Defense: How Mechanical Stress Fights Cancer For decades, medical professionals have noted a curious phenomenon: primary heart cancer is exceptionally rare. While most organs in the human body are susceptible to malignant growths, the heart seems to possess a natural resilience. Recent research published in the journal Science has finally provided a … Read more