Highlight Therapeutics announced positive Phase 2b results for its investigational intralesional basal cell carcinoma treatment, BO-112, at the European Academy of Dermatology and Venereology Congress in Vienna. The study met its primary endpoint of visual and pathological response at week 24 in patients with resectable primary low- and high-risk forms of the disease. Phase 2b … Read more
Drinking tea or coffee at very hot temperatures triples the risk of developing esophageal squamous cell carcinoma, according to a study published in the International Journal of Cancer. Researchers from the University of Oxford analyzed data from nearly one million UK adults, finding that individuals who prefer their beverages very hot face a significantly higher … Read more
Hepatocellular carcinoma, currently the sixth most common malignancy and the third leading cause of cancer-related death globally, is facing a paradigm shift in precision management according to a comprehensive review published in Cancer Biology & Medicine. Researchers from the Eastern Hepatobiliary Surgery Hospital at Naval Medical University in Shanghai and the First Affiliated Hospital of … Read more
Insilico Medicine published a collaborative study in the journal npj Precision Oncology, detailing how artificial intelligence and multi-omic analysis identified therapeutic targets in inverted papilloma-associated sinonasal squamous cell carcinoma (IP-SNSCC), a rare head and neck cancer. Conducted with researchers from the University of Chicago and Johns Hopkins University, the peer-reviewed paper offers the first comprehensive … Read more
Daily consumption of raw tomatoes and tomato sauce significantly reduces controlled attenuation parameter (CAP)-defined hepatic steatosis in adults with metabolic dysfunction-associated steatotic liver disease (MASLD), according to an exploratory randomized controlled trial published in the journal Nutrients. Researchers found that a six-week tomato-rich diet outperformed a tomato-free control group, dropping median CAP values by 35 … Read more
Breakthrough in Oral Cancer Research: New Immune Pathway Could Revolutionize Early Intervention Researchers at The University of Texas MD Anderson Cancer Center have uncovered a critical immune pathway linked to the progression of oral precancerous lesions into head and neck squamous cell carcinoma, offering a potential roadmap for early intervention. The findings, published in *Cancer … Read more
Hepatocellular carcinoma (HCC) is currently the third leading cause of cancer death, with patient outcomes hindered by late diagnosis and scarce early biomarkers. According to a 2026 review in the journal Gene Expression, advancements in multi-omics and liquid biopsy are shifting the clinical landscape by enabling more precise prognostic tracking and personalized immunotherapy selection, though … Read more
Obesity is associated with a distinct molecular program in breast tissue that drives the transition from premalignant lesions to invasive cancer, according to a study published in The American Journal of Pathology. Researchers found that tumors in obese patients rely on stress-adaptive pathways and microenvironment remodeling rather than classical invasive pathways, suggesting that metabolic health … Read more
The Looming Liver Cancer Crisis: A Global Shift in Risk Factors Liver cancer remains a significant global health threat, ranking as the third leading cause of cancer-related deaths worldwide. In 2022 alone, nearly 870,000 new cases were reported, with hepatocellular carcinoma accounting for almost 80% of these. A concerning trend is emerging: even as progress … Read more
The Double-Edged Sword: Navigating the Risks of GLP-1 Weight Loss and Diabetes Drugs The booming popularity of drugs like semaglutide and tirzepatide, initially designed for type 2 diabetes, has surged thanks to their remarkable weight loss effects. But as millions embrace these medications, a clearer picture of their potential side effects and long-term risks is … Read more