carcinoma

AI-Powered Target Discovery for Rare Sinonasal Cancer by Insilico Medicine

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Insilico Medicine published a collaborative study in the journal npj Precision Oncology, detailing how artificial intelligence and multi-omic analysis identified therapeutic targets in inverted papilloma-associated sinonasal squamous cell carcinoma (IP-SNSCC), a rare head and neck cancer. Conducted with researchers from the University of Chicago and Johns Hopkins University, the peer-reviewed paper offers the first comprehensive … Read more

Daily Tomatoes Reduce Liver Fat in MASLD Trial

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Daily consumption of raw tomatoes and tomato sauce significantly reduces controlled attenuation parameter (CAP)-defined hepatic steatosis in adults with metabolic dysfunction-associated steatotic liver disease (MASLD), according to an exploratory randomized controlled trial published in the journal Nutrients. Researchers found that a six-week tomato-rich diet outperformed a tomato-free control group, dropping median CAP values by 35 … Read more

Unlocking the Role of the Immune System in Oral Precancerous Lesions

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Breakthrough in Oral Cancer Research: New Immune Pathway Could Revolutionize Early Intervention Researchers at The University of Texas MD Anderson Cancer Center have uncovered a critical immune pathway linked to the progression of oral precancerous lesions into head and neck squamous cell carcinoma, offering a potential roadmap for early intervention. The findings, published in *Cancer … Read more

Optimizing Liver Cancer Treatment via Gene Signatures and Multi-Omics

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Hepatocellular carcinoma (HCC) is currently the third leading cause of cancer death, with patient outcomes hindered by late diagnosis and scarce early biomarkers. According to a 2026 review in the journal Gene Expression, advancements in multi-omics and liquid biopsy are shifting the clinical landscape by enabling more precise prognostic tracking and personalized immunotherapy selection, though … Read more

How Obesity Drives Invasive Breast Cancer: Key Molecular Pathways

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Obesity is associated with a distinct molecular program in breast tissue that drives the transition from premalignant lesions to invasive cancer, according to a study published in The American Journal of Pathology. Researchers found that tumors in obese patients rely on stress-adaptive pathways and microenvironment remodeling rather than classical invasive pathways, suggesting that metabolic health … Read more

Liver cancer burden rising globally amid shift to metabolic risks

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The Looming Liver Cancer Crisis: A Global Shift in Risk Factors Liver cancer remains a significant global health threat, ranking as the third leading cause of cancer-related deaths worldwide. In 2022 alone, nearly 870,000 new cases were reported, with hepatocellular carcinoma accounting for almost 80% of these. A concerning trend is emerging: even as progress … Read more

How GLP-1 drugs affect the body beyond weight loss and glucose control

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The Double-Edged Sword: Navigating the Risks of GLP-1 Weight Loss and Diabetes Drugs The booming popularity of drugs like semaglutide and tirzepatide, initially designed for type 2 diabetes, has surged thanks to their remarkable weight loss effects. But as millions embrace these medications, a clearer picture of their potential side effects and long-term risks is … Read more

Genetic ancestry influences tumor biology and survival in head and neck cancers

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Beyond Race: How Your Ancestry Could Predict Cancer Treatment Success For decades, cancer research has focused on lifestyle factors and readily observable demographics like race when analyzing disparities in outcomes. But a groundbreaking new study from the University of Maryland suggests we’ve been missing a crucial piece of the puzzle: genetic ancestry. Researchers have discovered … Read more

Lower-Dose Leuprolide Approved for Advanced Prostate Cancer

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New Hope for Prostate Cancer Patients: FDA Approves 3-Month Leuprolide Formulation The landscape of advanced prostate cancer treatment is evolving, and the recent FDA approval of a 3-month formulation of leuprolide mesylate (Camcevi ETM) offers a promising new option for patients. This long-acting injectable emulsion provides a convenient alternative to existing treatments, potentially improving adherence … Read more

Over a Third of US Adults Unaware of HPV

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HPV Awareness: A Look Ahead at Future Trends As a health journalist, I’ve seen firsthand the impact of the Human Papillomavirus (HPV). Recent studies, such as the one published in JAMA Oncology, highlight a persistent challenge: alarmingly low awareness of HPV and its vaccine across the United States. This lack of understanding directly correlates with … Read more

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