Cirrhosis

Daily Tomatoes Reduce Liver Fat in MASLD Trial

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Daily consumption of raw tomatoes and tomato sauce significantly reduces controlled attenuation parameter (CAP)-defined hepatic steatosis in adults with metabolic dysfunction-associated steatotic liver disease (MASLD), according to an exploratory randomized controlled trial published in the journal Nutrients. Researchers found that a six-week tomato-rich diet outperformed a tomato-free control group, dropping median CAP values by 35 … Read more

PPAR Receptors: A New Therapeutic Target for Rare Liver Disease

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Primary biliary cholangitis is a rare autoimmune disease affecting small bile ducts within the liver, causing bile to build up and trigger progressive liver damage that can eventually lead to cirrhosis, according to recent medical studies. Because the immune system attacks these vital ducts, roughly 40% of patients fail to respond adequately or cannot tolerate … Read more

Mexico Must Prioritize Liver Disease in Chronic Care: Expert Recommendations

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Metabolic dysfunction-associated steatotic liver disease (MASLD) may affect up to 47% of adults in Mexico, according to a review published in Archives of Medical Research. Lead author Jeffrey Lazarus, a professor at the CUNY Graduate School of Public Health and Health Policy, argues that Mexico must integrate liver health into existing obesity and diabetes programs … Read more

Colbopasvir plus sofosbuvir achieves high cure rates in chronic hepatitis C

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The New Frontier of Hepatitis C Treatment: Breaking the Barrier of “Difficult-to-Treat” Strains For years, the medical community has chased the “holy grail” of Hepatitis C (HCV) treatment: a regimen that is not only highly effective across all genotypes but also safe for patients with complex comorbidities. Recent real-world data from a multicenter study in … Read more

Liver cancer burden rising globally amid shift to metabolic risks

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The Looming Liver Cancer Crisis: A Global Shift in Risk Factors Liver cancer remains a significant global health threat, ranking as the third leading cause of cancer-related deaths worldwide. In 2022 alone, nearly 870,000 new cases were reported, with hepatocellular carcinoma accounting for almost 80% of these. A concerning trend is emerging: even as progress … Read more

Ultrasound advances offer noninvasive assessment of portal hypertension severity

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The Future of Portal Hypertension Diagnosis: Beyond Invasive Procedures Portal hypertension (PH), a serious complication of liver cirrhosis, is traditionally diagnosed using invasive procedures to measure the hepatic venous pressure gradient (HVPG). However, a growing body of research suggests a shift towards non-invasive methods, particularly advanced ultrasound techniques. A recent review published in Portal Hypertension … Read more

New pathway found connecting liver congestion to fibrosis and cancer

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Unlocking the Secrets of Liver Congestion: A New Pathway to Treatment Chronic liver congestion, a condition where blood pools in the liver, has long been recognized as a precursor to severe liver diseases like fibrosis and even cancer. However, the precise mechanisms driving this progression have remained elusive – until now. Researchers at The University … Read more

Predictive power of C-reactive protein shifts based on cirrhosis or coronary disease

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Inflammation’s Shifting Signals: How Disease Context Changes Heart Risk Prediction New research highlights a crucial nuance in how we interpret inflammatory markers like C-reactive protein (CRP). The predictive power of these markers isn’t fixed; it dramatically shifts depending on whether a patient is battling cirrhosis or heart disease. This discovery, published in the Bulgarian Society … Read more

Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality

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Liver Cirrhosis and Rising Bacterial Infections: A Global Health Concern Bacterial infections (BIs) are a significant threat to individuals living with liver cirrhosis, a condition affecting millions worldwide. A recent meta-analysis, published in the Journal of Clinical and Translational Hepatology, paints a concerning picture: these infections are not only common but are also on the … Read more

Expert guidance on fecal microbiota transplantation in liver disease

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Fecal Microbiota Transplantation: A Gut Feeling About the Future of Liver Disease Treatment For decades, the gut has been seen as a digestive workhorse. Now, groundbreaking research is revealing its profound influence on nearly every aspect of our health, particularly liver function. Fecal Microbiota Transplantation (FMT) – the process of transferring fecal bacteria from a … Read more

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