The U.S. Food and Drug Administration approved zenocutuzumab as a second-line therapy for NRG1-positive cholangiocarcinoma on May 8. According to results from the eNRGy phase 2 clinical trial published in the Journal of Clinical Oncology, the drug more than doubled the median progression-free survival to 9.2 months, compared to the approximately four months typically seen … Read more
A ten-week cognitive rehabilitation program significantly improves executive function and goal attainment for patients suffering from long Covid, according to a clinical trial led by University College London (UCL) researchers. Published in JAMA Network Open, the study found that 53% of participants receiving the therapy maintained substantial improvements six months later, compared to just 15% … Read more
Brain-computer interface (BCI) technology, long developed in isolated silos for vision and touch, relies on nearly identical neural and computational principles. According to a review published in Nature Reviews Bioengineering led by Giacomo Valle of Sweden’s Chalmers University of Technology, merging these fields could accelerate the development of prostheses for patients with sight loss or … Read more
A combination of dietary fibers from wheat, citrus, and oats significantly improves bowel movement frequency and stool consistency in adults with chronic functional constipation, according to a randomized clinical trial published in the journal Food Science & Nutrition. Researchers found that a daily 13-gram supplement dose containing resistant dextrin, pectins, and insoluble fiber provided faster … Read more
High-dose docosahexaenoic acid (DHA) supplementation successfully increases omega-3 levels in the human brain but fails to halt cognitive decline or structural brain changes, according to a randomized clinical trial published in eBioMedicine. Researchers monitored 365 older adults over two years, finding that while the supplement reached the central nervous system, it provided no measurable benefit … Read more
A new wearable neurorobotic system called SensoExo has demonstrated the ability to restore tactile sensation and grip control in patients with neurological hand impairments. Developed by researchers at the Medical University of Vienna, ETH Zurich, the Technical University of Munich, and the Medical Faculty Belgrade, the device combines a hand exoskeleton with transcutaneous electrical nerve … Read more
Targeted “nudges” sent to oncology patients and their clinicians significantly increase the frequency of critical end-of-life care conversations, according to a randomized controlled trial published in the JNCCN—Journal of the National Comprehensive Cancer Network. By combining patient questionnaires with clinician email reminders, researchers at the Dana-Farber Cancer Institute found that patients had 79% higher odds … Read more
New research published in Nature Medicine reveals that the medication dapagliflozin significantly reduces the risk of heart failure in patients who carry specific cardiomyopathy-associated genetic variants. Findings from the Mass General Brigham Heart and Vascular Institute and the Broad Institute of MIT and Harvard suggest that these genetic markers could help clinicians identify patients who … Read more
The recent breakthrough by the University of Cambridge and its spin-out, DIOSynVax (DVX) Ltd, marks more than just a successful clinical trial; it signals a fundamental shift in how humanity prepares for biological threats. The successful Phase 1 trial of the pEVAC-PS vaccine—an AI-designed, needle-free “universal” coronavirus vaccine—is a preview of a future where we … Read more
The End of “Reactive” Medicine: How AI is Ending the Pandemic Chase For decades, humanity has played a high-stakes game of cat-and-mouse with viruses. When a new pathogen emerges, scientists rush to sequence it, manufacture a targeted vaccine, and scramble to distribute it—often just as the virus begins to mutate into something new. We see … Read more