Multi-Omics Analysis of Coronary Heart Disease Networks
Integrated metabolomic and proteomic analyses reveal that coronary heart disease progression—from stable angina pectoris to acute myocardial infarction—features a dramatic escalation in molecular pathway crosstalk, culminating in a tightly coupled “molecular storm” characterized by heavily connected hubs such as L-glutamate and KNG1. Stage-by-Stage Pathway Expansion in Coronary Heart Disease The number of pathways co-enriched in … Read more