crispr

Bing Yang leads team using AI gene-editing to create rice resistant to blight

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White Rice Ears

According to SciTechDaily on May 20, 2026, researchers have created an innovative method to shield rice from a harmful bacterial disease endangering global harvests. An artificial intelligence-designed gene-editing tool helped researchers create rice plants resistant to bacterial blight, a pathogen that attacks crops across Asia and Africa. Bing Yang, a Curators’ Distinguished Professor in the … Read more

How DNA Typewriters Record Mouse Embryo Cell Lineage

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How DNA Typewriters Record Mouse Embryo Cell Lineage

Researchers at the University of Washington School of Medicine have tracked the lineage of 1.3 million cells in a mouse embryo across nearly two weeks of development using a molecular tool called DNA Typewriter. The technology records the chronological history of cell divisions from a single-celled zygote to a multi-tissue organism. Mapping Cell Division With … Read more

New Gene Editing System Outperforms Traditional CRISPR Technology

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New Gene Editing System Outperforms Traditional CRISPR Technology

Researchers at Cornell University have engineered a new non-CRISPR gene editing tool that can insert large blocks of DNA into a genome at a precise location and in a single orientation. Described in a study published in Molecular Cell and reported by BioTechniques, the RNA-guided transposition system addresses limitations in current editing technologies by allowing … Read more

TIGRa: A Smaller Gene Activation Platform for In Vivo Delivery

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Stanford Medicine researchers have developed a compact gene activation platform named TIGRa, which is less than half the size of conventional CRISPR-based activators and capable of in vivo delivery via adeno-associated viruses, according to a proof-of-concept study led by Yang Sun. Understanding the TIGRa Gene Activation Platform The CRISPR-Cas9 system revolutionized genome editing and targeted … Read more

AI-Designed Nucleases: Enhancing Nature’s Genetic Tools

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Researchers led by Nobel laureate Jennifer Doudna at the Innovative Genomics Institute and the University of California, Berkeley, have successfully used generative AI to design novel RNA-guided nucleases, a breakthrough in synthetic biology. By combining evolutionary data with inverse protein-folding models, the team created "SynTnpBs"—synthetic variants of TnpB proteins—that match or exceed the editing performance … Read more

Scientists Successfully Remove Down Syndrome Chromosome

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Researchers at Mie University in Japan have successfully used the CRISPR-Cas9 gene-editing system to excise an extra copy of chromosome 21 from human cell lines. According to the study published in PNAS Nexus, this process restored near-normal cellular function, including improved mitochondrial efficiency and faster growth rates in stem and skin cells, marking the first … Read more

New CRISPR RNA scissors specifically target and destroy hepatitis E virus

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The Next Frontier in Antivirals: Using RNA ‘Scissors’ to Combat Hepatitis E For years, the conversation around CRISPR has been dominated by the ability to edit DNA—the permanent blueprint of life. However, a paradigm shift is occurring in medical research. Instead of altering the host’s genetic code, scientists are now deploying “molecular scissors” that target … Read more

Scientists Identify Gene Behind Limb Regeneration, Moving Closer to Human Application

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Beyond Prosthetics: The Quest to Wake Up the Human Regeneration Switch For decades, the idea of regrowing a lost limb was relegated to the realm of comic books and high-concept science fiction. But recent breakthroughs in genetic research are shifting the conversation from “if” to “how.” The discovery of the SP8 gene—a molecular switch that … Read more

New study reveals CRISPR enzyme that responds to human DNA methylation

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For decades, the “Holy Grail” of oncology has been a treatment that kills cancer cells while leaving healthy ones completely untouched. Chemotherapy, for all its success, remains a blunt instrument—a molecular sledgehammer that hits everything in its path, leading to the grueling side effects we’ve arrive to associate with cancer treatment. But we are entering … Read more

SP8 Breakthrough: A Foundational Step Toward Human Limb Regeneration

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Beyond the Bionic Arm: The Dawn of Biological Limb Restoration For decades, the gold standard for treating limb loss has been the prosthetic. We’ve seen incredible leaps in robotics—carbon-fiber blades and neural-linked bionic hands—but these remain external tools. They mimic function, but they don’t replace the living, breathing complexity of human tissue. Recent breakthroughs in … Read more

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