Six men aged 18 to 51 have been sentenced for drug trafficking to terms ranging from six months’ imprisonment at home to 18 months in prison, eight of which are suspended, details the Dijon public prosecutor Eric Mathais in a press release, this Friday. Two other youths asked for time to prepare their defense. They have been placed under arrest warrant and will be tried on July 28. A 17 year old minor was placed in a closed educational center.
In the other part of the investigation into the violence that took place from 12 to 15 June in Dijon, which concerns the possession of weapons, five other people, aged 21 to 41 years and living in Côte d’Or, suffered from 3 to six months of house arrest with bracelet or 140 hours of community service. All are prohibited from carrying or holding a weapon for five years.
Arrested during weapons search operations
All these people had been arrested during arms search operations, four in less than a week (Friday June 19, as well as last Monday, Wednesday and Thursday), which had been triggered following the disturbances that had occurred in particular in the sensitive Grésilles district.
In the evening of Monday, June 15, hooded men appeared on videos fitted with what appeared to be assault rifles or automatic pistols, fake or real. The prosecutor recently pointed out that some of these images had not been filmed in Dijon.
Nine people were arrested during the Monday operation and eight during the Wednesday morning operation, followed by another arrest later in the day.
Fourteen people had been taken into custody until Friday. Three were released and released while a final was called on July 2 for ” participation with a weapon in a crowd by a person deliberately concealing his face ».
The violence in Grésilles and Chenôve, in the outskirts, had taken place after a series of reprisals launched by members of the Chechen community, who wanted to take revenge on the aggression of a teenager whom they attribute to dealers in sizzles.
In the investigation into these facts, six Chechens were arrested on Thursday June 18. Two were exonerated, while the other four were indicted, including three placed in pre-trial detention. The fourth suspect remained free under judicial supervision.
Bertoneri in combination with chemotherapy affects the DNA of cancer cells, not allowing her to recover.
Photo: depositphotos.com
Specialists from the Institute of cancer research UK are looking for new ways to fight cancer. British scientists have focused on the ability of cancer cells to restore DNA. In the course of studies has identified the ATR protein, which is responsible for the repair of cells, which were exposed to the drug personaltab. Scientists did not expect so much positive effect, because the British drug in combination with chemotherapy 70% decreased the growth of aggressive tumors. Experts believe that made a breakthrough in the treatment of severe forms of cancer, because patients with such diagnoses have experienced a new drug.
The success of the operation personeria is that chemotherapy also affects the DNA of tumors makes them more sensitive to the ingredients of the new drug. To date, the side effects of the drug are mild and do not go to any comparison with the benefit from personaltime. Scientists are going to continue to create tools that act on the DNA of cancer tumors.
The national institutes of health (NIH) stopped its clinical trials of anti-malarial drug hydroxychloroquine after found that treatment does not benefit patients with COVID-19. The decision to terminate the test was made after the Department of supervision of food and drug administration has revoked the emergency use of the drug, and the world health organization expelled him from their global study.
Hydroxychloroquine is a medicine against malaria, in some countries, used for the treatment of patients with coronavirus. The Ministry of healthcare shall also consider hydroxychloroquine as a means to prevent COVID-19. The drug trial was previously suspended due to reports of increased mortality among patients taking the drug.
“The monitoring Committee data and safety gathered late on Friday evening and determined that, although there was no harm, the study drug is unlikely to be useful for hospitalized patients with COVID-19″— said in the statement said the NIH (quoted by CNBC).
The President of the United States Donald trump earlier said that regularly taking hydroxychloroquine for prevention. He said that his doctor didn’t recommend him the drug, but he asked it the White house doctor.
Read more about the use of the drug President of the United States — in the material “Kommersant” “the Drug of his Excellency”.
A new device intended, according to the government, to reduce the increase in the number of consumers of narcotic drugs, particularly cannabis, is going to be tested in the cities of Rennes, Reims and Creteil from the 16th of June. Violators will have to pay 200 € (amount reduced to € 150 and increased to 450 € depending on the time of payment). The use of narcotic will be perceived by users as a minor offence, in the same way that an excess of speed on the road, and will without doubt contribute to trivialize in the public opinion.
Prison sentences are rarely carried out
How did it come there, while France is known for having a law, as opposed to repressive, providing for up to a year in prison and 3 750 € fine ? Simply because this legislative arsenal is not, or little, applied the ordinary. In the case of traffic, supply of narcotic drugs leads to the same prison sentences are rarely carried out, if we compare the situation to other european countries.
According to a study by the european monitoring centre for drugs and drug addiction (EMCDDA), published in 2017, covering 25 countries, in Greece the offer of a kg of heroin led to a penalty, with a median of 20 years in prison and the supply of one kg of cannabis to 10 years in prison. At the other end of the scale we find both the most tolerant countries, the netherlands and France, where the offer of a kg of heroin led to a penalty median of the respective 1-year and 2-years in prison. The situation has been further relaxed by the act Tubiana.
In France, often the development of sentence leads to the immediate payment of a fine and extinguishes the public action. Few of the defendants actually perform their prison sentences.
“Hitting the wallet “
In the Face of this situation, it is understandable that police officers and gendarmes involved in the fight against the illicit use of narcotic drugs are discouraged to see that their work does not allow to translate the users and the traffickers (the distinction is often difficult to establish) before the courts.
Then, again, one chooses the facility… We are going to ” hit to the wallet “, hoping that this measure is liable to dissuade the consumer from consuming. However, the addiction to cannabis (often followed by addiction to cocaine) is known to be very strong, leading to the search of substances of a more proportioned.
A fixed penalty will never deter a consumer at the point of the renunciation of the use of its drug. Especially if it is part of the population, little affected by the payment of a fine even high. To the contrary, this device does it not push more applicable to some individuals, less-fortunate, to seek by every means, including violence, to support their consumption ?
300 000 children aged 12 to 15 years
This new rule is the opportunity, once again, found that no public health response is planned to combat this scourge. However, it is to forget the harms of cannabis on the health, not only in adults but especially in young adolescents.
In France, 1.6 million regular consumers of cannabis and 300 000 children 12-to 15-year-olds have already experimented with this drug.
Cannabis is not a drug, “soft” : a large number of scientific papers and statistical studies have demonstrated definitively that he is a ” drug, hard “, which causes an addiction to be extremely strong, aggravated by the association with tobacco and alcohol, and leading very often to “escalation” to other drugs even more harmful (cocaine, heroin).
Many mental health disorders, domestic violence
By its high solubility in lipids, the active ingredient, THC, is associated to cell membranes, can move easily across the blood-brain barrier and accumulate in the brain.
In adolescents, where this organ is in course of maturation, he causes many mental disorders : disturbance of memory, focus of attention, ataxia, motor incoordination, disinhibition can lead to risk-taking, induction of raptus aggressive against oneself or directed against another person, potentiation of the effects ébriants or hallucinogenic, psychiatric disorders (schizophrenia), anxiety, and depression.
The use of cannabis in the adult often leads to displays of aggression, violent. The analysis of the facts shows that much of the violence observed during the recent confinement occurred in the context of cannabis.
Treat it as a disease
It is necessary to consider, therefore, that the consumer of cannabis is first and foremost a patient and it must be treated as such. Even if it is to be deplored that the sentences are not very often applied, the passage in front of the judge at least allows him to decide the requirement of treatment. With the application of the fine, this possibility disappears.
Ultimately, we are still waiting for a true policy to fight against drug abuse, which would imply, in particular, a prevention program as early as primary school, as is the case in Sweden, for example. When the public authorities take awareness of the importance of the health problem posed by drug addiction ?
(*) Pr of Biochemistry (University of Caen), a Member of the CNPERT (National Centre of Prevention, Studies and Research on Addictions)
The formula will be patented and then seek a global manufacturer for large-scale production
According to experts, it is “an important step towards finding a antidote to the coronavirus. “The director of the Institute, Shmuel Shapira, said that the formula of the antibody will be patented and then look for a global manufacturer for the production on a large scale.
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“We often go on autopilot, and instead of understanding if we like alcohol, or how it makes us feel, we follow friends and drink what they drink, without awareness”
If in my first twenty years I drank to drink, now I only drink if I like something. The derogation can be, at most, a gin and tonic in a plastic cup at a concert or an industrial beer on the beach. I do a job that exposes me to alcoholic opportunities so I always try to keep a few alcohol-free days a week. I still go overboard but less and less (and with ever-worse aftermath of the hangover) and no longer intentionally. IT WILL NOT BE PRACTICAL ALREADY MINDFUL DRINKING WITHOUT KNOWING? Should I write a book on it?
The term was born from a book written by the journalist Rosamund Dean in 2017 that promises to help cultivate a new, healthy and aware relationship with alcohol: not to quit, but to moderate
I speak now of Mindful Drinking not surprisingly: from the photos of old people who display signs asking for alcohol to the memes on the alcoholic breakfast it seems clear that everyone (all those who habitually consume alcohol) is drinking even more than usual. It is an unimaginable stress situation. I am not surprised that the consumption of alcohol has increased as well as, given in hand, the consumption of “comfort” food has increased. One example above all: in quarantine the home delivery company Winelivery recorded increases of 250%.
But this deregulation is it dangerous to alcohol? If we can shrug and say “Okay, I’ll open a bottle again tonight, I don’t have to drive, I have two aperitifs on Zoom and then oh, there is a world pandemic”, what are the effects on the long term? Are we at risk of compromising our health or creating an addiction?
What is mindful drinking
A few days ago I ran into an article on mindful drinking. The name is borrowed from mindful eating, in which the principles of mindfulness are applied to eating, as the psychotherapist explains to me Lara Ferrari: “Often it is trivialized and it is thought that mindful eating is just tasting the food focusing on the sensations. In the protocol taught in the ME courses, the daily practice of conscious nutrition is accompanied by a formal meditative practice. It is a non-prescriptive approach, unlike “traditional” diets, which does not have weight loss as its main purpose but the reappropriation of a peaceful relationship with food. It is a path that begins with a psychologist and not with a nutritionist or dietician. “
“He suggests pretending to drink gin and tonic, while instead it’s just tonic water, so ‘none of your friends will make fun of you.’ But what kind of friends do you have?”
It seems almost counterintuitive to talk about meditation techniques applied to drinking. And indeed Mindful Drinking turns out to be anything but a formal meditative practice. Apparently the term originated from a book written by the journalist Rosamund Dean in 2017 that promises to help cultivate a new, healthy and aware relationship with alcohol: not to stop, but to moderate. The book is part of a movement that has grown exponentially in recent years, especially in the United States, which does not want to push people not to drink but to drink less, as the CLUB SÖDA NYC, a network that organizes non-alcoholic events.
And even the Mindful Drinking festival was born. Sifting online (no, I didn’t want to buy the book), it seems that the basic principles are: to make a preventive plan of when to drink, what to drink, where; don’t be bribed (with frankly ridiculous advice like pretending to drink a gin and tonic when it’s just tonic water so none of your friends will make fun of you – but what friends do you have?); do not drink as a relief mechanism from negative emotions. Dean says she personally sets the rule of three: three days a week, maximum three drinks. A prescriptive approach decidedly different from that of mindful eating.
“Let’s start by asking ourselves questions: what am I drinking the best choice for me? How does it make me feel? It will make it easier for us to stop when we want.”
“I don’t like alcohol so I don’t text!” Ferrari laughs. “First of all we must differentiate those who have problems related to alcohol consumption from the so-called social drinker. We often go on autopilot, and instead of understanding if we like alcohol, or how it makes us feel, we follow friends and drink what they drink, without awareness. Let’s start by asking ourselves questions: what I’m drinking the best choice for me? How does it make me feel? It will make it easier for us to stop when we want. “
Ferrari notes that this approach may be better than “all or nothing.” When we have rules, we always tend to transgress them. We don’t drink anything for a while, then we give the go-ahead … and we end up feeling very bad. “Mindful drinking and mindful eating are not perfectly superimposable but” surely it is useful, while drinking, to realize if you do is doing to handle negative emotions. A bit like emotional eating. It happens to eat a biscuit just to get up or drink a glass of wine if you are depressed or angry. But it would be better to realize what emotions are underneath and wonder if alcohol, or food, are the only way we manage them, those emotions. In this perspective, mindful drinking can perhaps help us regain possession of moderate drinking.“
Unfortunately I have to remind you of one thing. The Ministry of Health found itself forced, among other fake news, to deny the alleged beneficial properties of alcohol. And he took the opportunity to add that “Abusing it increases the risk of infection because it “damages all components of the immune system” […] In fact, there is a dose dependent correlation between alcohol consumption and viral infections. ”
Another reason why getting drunk every night on the sofa is not exactly a brilliant idea. Remembering that moderation is also needed in moderation: as soon as I see my friends again, I plan to take a colossal hangover. But above all remembering that, if you are afraid of developing an addiction to alcohol, there is no shame in asking for help.
35 molecules discovered to fight the SarsCoV2 virus, thanks to a computing power similar to that used by Italy to discover the Higgs boson; one belongs to the isoxychloroquine family. Described on the ArXiv website, they will now be able to take tests to find out if they can become anti-Covid-19 drugs. They were selected from the 9,000 analyzed by the project led by the Sibylla Biotech company and by the National Institute of Nuclear Physics (INFN).
Remdesivir is one of the most promising agents in the fight against coronavirus and is already used in individual cases to treat patients.
Remdesivir is one of the most promising agents in the fight against the novel coronavirus and is already used in individual cases to treat patients. Random clinical trials with remdesivir are already underway in several countries.
According to the Stat website, which specializes in health issues, the drug has had a great effect on corona patients in a Chicago hospital that is participating in the clinical trials. Remdesivir has also been used to treat Ebola.
Promising drug against Corona
You may have to wait longer for a vaccination, but there is now a glimmer of hope in terms of medication. An ingredient called Remdesivir appears to be promising.
Senior doctor explains how Remdesivir works
In order to accelerate the development of treatment options for SARS-CoV-2, pharmaceutical companies may provide medicines that have not yet been approved, which can then be used in the course of clinical trials or as part of medical trials under high safety requirements. The US company Gilead has also announced that it intends to donate the entire medium-term quantity of its drug under development (Remdesivir).
Gilead had promising drugs in development many years ago when SARS and MERS pathogens first appeared. The company can now build on this and there is hope that a successful result will be achieved faster than usual.
The medicine was also used by Austrian clinics on the basis of individual healing experiments.
Treatment success in monkeys
In a small-scale experiment on monkeys, the first treatment successes with remdesivir against coronavirus-induced lung disease Covid-19 were shown. According to scientists commissioned by the US government, the state of health of the monkeys treated with the virus-inhibiting agent improved significantly after just twelve hours.
The preliminary study results have not yet been independently assessed. For the experiment, the scientists deliberately infected two groups of six rhesus monkeys each with the pathogen SARS-CoV-2. One of the two groups was given Remdesivir, an agent developed by the pharmaceutical company Gilead Sciences, twelve hours after the infection, but not the control group.
Remdesivir – Ulrich Perrey / POOL / AFP
Get better after just 12 hours
The researchers administered the drug to the treatment group monkeys shortly before the virus concentration in the lungs peaked. According to the scientists, the health status of the treated monkeys improved significantly 12 hours after receiving the first dose of remdesivir. According to the study report, this trend continued over the entire one-week study period.
According to the researchers, one of the animals in the treatment group had slight breathing difficulties despite the remdesivir therapy. In the control group, however, the health status of all six monkeys deteriorated rapidly. All of them had severe breathing difficulties.
Less viruses and lung damage
The researchers found a significantly lower virus concentration in the lungs of the monkeys treated with Remdesivir than in the untreated monkeys. Lung damage was also less in the animals in the treatment group.
Global 155 drugs and 79 vaccinations in development
A survey by the Austrian Institute for Health Technology Assessment (AIHTA) shows that a total of 155 drugs and 79 vaccinations to combat Covid-19 are currently being worked on worldwide. Accordingly, most of these drugs under development are already approved for other infections. So far, none of the vaccine candidates have reached the developmental stage.
The 155 drugs currently tested for their activity against SARS-CoV-2 are all based on one or more antiviral agents: These are remdesivir, lopinavir and ritonavir (trade name: Kaletra), favipirvir (Avigan), darunavir (Prezista), chloroquine Phosphate (Resochin), Hydroxychloroquine (Plaquenil), Camostat Mesilate (Foipan), APN01 (rhACE2), Tocilizumab (Roactemra), Sarilumab (Kevzara) and Interferon beta 1a (SNG001). “Since the majority of these active ingredients are drugs that are already approved for other indications, international regulators emphasize the need for robust evidence, that is, approval studies for the effectiveness of Covid-19,” said AIHTA director Claudia Wild.
The vaccine candidates identified by the AIHTA are live vaccines, i.e. with weakened virus strains, dead vaccines that contain virus proteins, or gene-based vaccines with special DNA or mRNA. Most of these projects are currently still in the development stage and are not yet approved.
Eleven drugs and eight vaccine candidates are particularly advanced in development and are considered to be particularly promising in the specialist literature. For these, the experts have written brief descriptions with additional information.
: Treatment success with remdesivir against Covid-19 in monkeys
Icon image. Photo: dpa / Hendrik Schmidt
Washington In a small-scale experiment on monkeys, the first treatment successes with remdesivir against coronavirus-induced lung disease Covid-19 were shown.
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As scientists commissioned by the US government announced on Friday, the health of the monkeys treated with the virus-inhibiting agent improved significantly after just 12 hours. The preliminary study results have not yet been independently assessed.
For the experiment, the scientists deliberately infected two groups of six rhesus monkeys with the pathogen Sars-Cov-2. One of the two groups was given Remdesivir, an agent developed by the pharmaceutical company Gilead Sciences, twelve hours after the infection, but not the control group.
The researchers administered the drug to the treatment group monkeys shortly before the virus concentration in the lungs peaked. According to the scientists, the health status of the treated monkeys improved significantly twelve hours after receiving the first dose of remdesivir. According to the study report, this trend continued over the entire one-week study period.
According to the researchers, one of the animals in the treatment group had slight breathing difficulties despite the remdesivir therapy. In the control group, however, the health status of all six monkeys deteriorated rapidly. All of them had severe breathing difficulties.
The researchers found a significantly lower virus concentration in the lungs of the monkeys treated with Remdesivir than in the untreated monkeys. Lung damage was also less in the animals in the treatment group.
Remdesivir is one of the most promising agents in the fight against the novel coronavirus and is already used in individual cases to treat patients. Random clinical trials with remdesivir are already underway in several countries. As the health website Stat reported on Thursday, the drug had great effect on corona patients in a Chicago hospital participating in the clinical trials.
Remdesivir has also been used to treat Ebola. At the beginning of April, the Federal Institute for Drugs and Medical Devices (BfArM) approved a so-called hardship program, in which severely affected corona patients may be treated with remdesivir outside of a clinical trial in hospital, although there is still no official approval.
It’s a bit like “Qüity and Cleo at the Villa»(And, in addition, with the Virgin) as there is Martine at the sea. Except that not at all. These are lives of misery filled with riches told with a catchy fantasy that explains this title, Full of grace. “Villa” here does not mean luxury but slum, “Villa miseria”. Argentina’s novel Gabriela Cabezón Cámara, born in 1968, begins when the two lovers left Buenos Aires and this “Villa” who suffered legal carnage, for Miami where a “Cumbia opera” allowed them to build a fortune. He tells the story of community life in the slum at full speed.
Most often, Qüity is the narrator, and sometimes Cleo. This is a transvestite who has abandoned prostitution. “About to suffocate in her own blood and in the semen of the whole police station, she had had a vision: the Virgin”, and the two will never let go. Qüity is a young journalist who went on a report to the “Villa” which does not have “Never been able to return from the other side of the world, that of those who live far from the small Auschwitz that we find in Buenos Aires both blocks away”. Qüity is the writer and has no morale at the start of the book. “I felt stranded and thought I had survived a shipwreck. I now know that no one survives a shipwreck. Those who sink die and those who get out live by drowning. “ Cleo will blame him for writing “Any bullshit”,“You have no imagination, you need things to happen so you can write them”. A child died before his eyes while searching “His favorite plush, the bald cook”, when the “Villa” has been cleaned.
It’s not just the Virgin being “Full of grace” but she’s the one who best describes the tone of the novel. Cleo wants to build her a “Nomad cathedral”, Qüity is appealing to a “Psychiatric treatment” for his partner, but here is how, over the chapters, one or the other evokes the mother of Jesus, the son in question and the stories swarming around this family. “And then, yes, we have the right to be selfish like all mothers in the world, even the Virgin says it: if it was up to her, Jesus would have been a carpenter and would have married Marie Madeleine, Even though she was a bit of a whore, it was still better than playing the prophets and getting married with a cross. ”“The host disappointed me that a few years later I would be disappointed with the drugs, even if I insisted more on coke than on God.” “She [la Vierge, ndlr] gave me the Bible to read. It’s super long. ” “She says you can’t know what it was like to pretend to be speaking as a single Jewish mother fifteen years ago two millennia ago.” Until : “And little by little I remembered and I cried, cried, cried with great cries and I insulted the Virgin in every way, I told her the most horrible things that came to my mind, “holy nitouche” was the sweetest, then I ended up saying much worse things, “grumpy”, I said to her, “treacherous daughter of a bitch”, I said to her, “a bitch raped by a pigeon, submissive and accomplice of this son of a bitch of God “». There is an original vision of Jesus in anti-Robin Hood demanding to “give back to Caesar” what belongs to him.
Full of grace also tells the life of the slum dwellers among the wealthy, the girl killed by vice, for the enjoyment of others, which offends a good friend of Qüity, “Stoic man who believed in murder without pleasure”. There are internships offering “Such difficult employment opportunities that even Theseus would never have found a job in such a labyrinth” and this moment when “The villa was filled with people, students, photographers, NGO activists who administered the tithing of guilt […]”
It changes from Miami where Qüity, from the beginning of the novel, became “Bunker freak”. “I know it now, but I can’t stand the slightest noise anymore, I think that if someone put cumbia on the bottom, I would shoot on sight. […] Curiously, this isolation is what best marks my adaptation to American society. I am part of the Bunker’s Club, an association of barjots locked in incubators as inviolable and impenetrable as they are autonomous. ” Life was different in the Villa in full activity, when it was really life but this troop was not equipped for combat. “Alone would have been enough to transform us into an army, but once we became a regiment we would have ceased to be what we were: a small and happy multitude.”
