Merdeka.com – One of the health problems that are currently being discussed is Happy Hypoxia. This problem is one of the symptoms experienced by COVID-19 patients.
Erlina Burhan, a pulmonary specialist in the Infection Division of the Department of Pulmonology and Respiratory Medicine, University of Indonesia (UI), revealed the symptoms of Happy Hypoxia that need to be known.
According to him, Happy Hypoxia is a decrease in oxygen levels in COVID-19 patients that the patient is not aware of. The patient may show a healthy body condition when in fact he is lacking oxygen. Generally, Happy Hypoxia occurs in symptomatic patients.
“It’s rare for a patient without symptoms,” he said in a BNPB press conference on Wednesday (16/9).
Symptoms of Happy Hypoxia that can be experienced by patients are usually characterized by a cough that persists for some time and gets worse, the body feels weak, and the color of the lips and fingertips becomes bluish.
“Don’t wait for tightness because in Happy Hypoxia there are generally no symptoms of tightness,” he said
If you already experience these symptoms, you must immediately be rushed to the hospital, he added. Because the only drug Happy Hypoxia is oxygen.
Happy Hypoxia Prevention
The first thing you can do to prevent Happy Hypoxia, says Erlina, is to know the symptoms.
“Another way is to frequently measure oxygen saturation with pulse oximetry, don’t wait for tightness,” he said.
An even more basic way is to prevent the disease from catching COVID-19. According to him, the way it is very easy to return to 3M is to wear a mask, wash your hands with soap and keep your distance.
Another thing that needs to be done is to increase the immune system. This can be achieved by consuming nutritious foods, getting enough rest, not smoking, taking supplements, and avoiding stress.
Reporter: Ade Nasihudin Al Ansori Source: Liputan6.com[RWP]
OPEN LETTER TO ARGENTINE SOCIETY IN THE MIDST OF THE PANDEMIC
Today, we pass through Argentina, the most difficult moment of the SARS-CoV-2 pandemic, measured both in terms of new infections as well as the increasing number of people who die every day. If additional measures are not implemented, this situation will continue to worsen day by day. In this context, the Faculty of Medicine of the University of Buenos Aires together with the signatory Medical and Scientific Societies, concerned about Public Health, communicate our position to the different government bodies, to our colleagues and to society as a whole.
Social distancing continues to represent the fundamental measure in the fight against the pandemic. We observe with great concern a relaxation in the fulfillment of the rules of distancing, which does not respect geographical limits or political districts. We make an energetic appeal in this regard that includes both governments and each and every citizen. We are talking about thousands and thousands of deaths that can be avoided.
Search devices for infected people with and without symptoms (but still contagious) and close contacts should be put into operation more quickly. To this end, you must dramatically expand our diagnostic capacity, implementing a more aggressive and active logic. What we have done so far in this area is clearly insufficient. Although to this day, mortality is lower than in many countries, our number of infected and deceased continues to increase.
The health personnel have made and continue to make an extraordinary effort. Day by day they put their health at stake, and that of their loved ones. It is essential to acknowledge their work and pay our warm tribute to them. We urge the authorities to urgently request strengthen the health system, by incorporating suitable personnel and adequate equipment, and recognizing those who have long been ignored and devalued. We ask society and governments to help us take care of and take care of us.
We are exhausted from working in this context and under these working conditions. The pandemic affects us all, the fear of getting sick and dying is present in society, and the fatigue due to distance and confinement is increasing. Doctors, nurses, kinesiologists, and other health workers are also stressed and exhausted from working continuously and without rest, for 160 days, in a system that does not recognize us, that does not take care of us, or provides the necessary protection elements for our work. We too get sick, we die. No one should be without work, but what is certain, no one should lose their life to work, and this is happening to us.
We are very concerned about the increase in community circulation, the lack or misuse of chinstraps and masks, the fact that distancing measures are not respected, social gatherings without care, because this leads directly to an increase in infections, disabilities and deaths. It is necessary to increase our awareness of risk, as individuals and as a society. We all want to believe that the worst is over, but it is not, and it will not happen as in stories or dreams, that things happen just by wishing them. The increases in cases in the interior of the country and “plateaus with high numbers” in some cities, only herald new cases of disease, and not even societies with very advanced health systems, were able to sustain the risk of illness, without having to suffer a huge number of victims. It is not possible that the need for the freedom to have a coffee, expose us to more loss of life. We need society to make these situations of “lack of individual and community care” visible as problematic. For now, the best remedy we found was distancing, and protective measures, and in the meantime, we will also continue investigating vaccines, plasma, serums or some medicine.
Now is when, responsibly and as an adult society, we must assume the responsibilities that correspond to us, as a community, as individuals and as governments, and take charge of health care and life for ourselves and our people
SIGNATORS
Dr. Jorge Geffner, Chair of Immunology
Dr. Carlos Rojo, Graduate Cloister, Edgardo Knopoff School of Medicine. School of Public Health
Claudia Negri. Secretary of Degree and Courses
Dra. Angela Gentile, Argentine Society of Pediatrics
Raquel Wainsztein, Department of Pediatrics,
Dr. Perez Rosales, IAR
Dr. Luis Sarotto, Department of Surgery
Dr. Adrian Desiderio, Department of Surgery
Dr. Pascual Valdez, Argentine Society of Medicine
Dr. Pablo Rossini, Intensive Therapy Specialist Career
Dr. Guillermo Chapero, Argentine Society of Intensive Care
Dr. Ignacio Brusco, Department of Psychiatry and Mental Health
The general public remembers Deep Blue, seasoned opponent and ultimately executioner of Garry Kasparov. The poker community remembers the names of Polaris, who in 2007 had made a mixed copy after a series of duels against Phil Laak and Ali Eslami, and Tartanian7, which hit the headlines a few months ago after Card Player published an interview with its creator.
The newcomer is called Cepheus. Like its predecessor Polaris, this poker-loving computer program owes its existence to researchers at the University of Alberta. And like Tartanian7, it recently had the honors of the international press (Science, The Guardian, The Washington Post) and French (The Parisian) because of his mastery at the tables of Limit Hold’emHeads Up.
Talking about mastery even seems below the truth since according to its developers, Cepheus simply cannot be beaten in the long term. It is also this invincibility which allows them to say that Limit Hold’em Heads Up is “solved”. A status that the variant now shares with many other long-standing “solved” games, such as checkers or the precise 4th power. The Parisian.
But for a game with imperfect information, this is a great first and therefore a real leap forward for artificial intelligence. A leap that its creators attribute first to recent advances in algorithms, then to a supercomputer job whose figures make you dizzy: two months of training, 4,000 processors running simultaneously, and six billion hands considered per second.
As for the final stages of his progress, Cepheus owes them to astronomical amounts of disputed hands … against himself. Like any player who wants to improve, the program has looked at his history, analyzing his moves and correcting his little habits over time. Today he would have become “so close to perfect that after playing the equivalent of a lifetime of poker against him, that is, sixty million hands, you can’t tell the difference“.
If you still doubt it, go tothis page to form your own opinion. Tired of solo games, Cepheus indeed welcomes to his table anyone who wishes to compete with him. Before perhaps one day trying to play in No Limit or in multiway, formats which due to their complexity should keep their share of mystery in the eyes of artificial intelligence for a long time to come.
Cloving hospital on the basis of the Medical Scientific and Educational Center (ISSC) Moscow State University named after M.V.Lomonosov took the first patients on April 21 and completed his work on June 13. It turned out that it was possible to achieve the best treatment results for COVID-19 in Moscow. Over the entire period, 4 patients died, and among severe patients who got mechanical ventilation, the mortality rate was less than 14% (for comparison, the average for the city and the world was up to 70 – 80%). Eighteen doctors out of 220 employees of the hospital were infected with coronavirus, there were no deaths among the medical staff.
What approaches were used at the University Hospital of Moscow State University to achieve such results? We continue the conversation with the head. Department of Therapy, Faculty of Fundamental Medicine, Moscow State University, Head of the Department of Age-Associated Diseases, Medical Scientific and Educational Center, Doctor of Medical Sciences, Cardiologist Yana Orlova.
MEDICINE FOR COUGH FOR 80 RUBLES
– Most of those who are ill or are afraid to get sick are worried about fibrotic changes in their lungs. They say that you have developed special therapy that can reduce the risk of developing fibrosis. Is it possible?!
– Yes, we launched an appropriate clinical study. There are no final results yet, but we have developed clinical practice.
“What did you do to save the lungs?”
– We used a combination of bromhexine and spironolactone (both are long-known very cheap drugs. – Ed.). Bromhexine is an expectorant that has been prescribed to patients with pneumonia and cough for many years. At the same time, experimental data showed that this drug can block a specific enzyme and impede the penetration of coronavirus into cells. True, it was on this effect that we counted to a lesser extent in inpatients, since such an effect is important mainly in the early stages of the disease. But the expectorant effect of bromhexine really helps patients with COVID. I heard that our colleagues in Peter launched a study of bromhexine for prophylactic purposes. We will wait for the results.
Coronavirus infected 18 doctors from 220 employees of the hospital, there were no deaths among the medical staffPhoto: Ivan MAKEEV
FIBROSIS OBSTACLE
– The second drug – spironolactone – is traditionally widely used in cardiology for the treatment of heart failure, severe hypertension. It has a small diuretic, magnesium and potassium-preserving effect, continues Yana. Orlova. – It has several mechanisms through which it can be useful in coronavirus infection.
Firstly, a mechanism that prevents the development of fibrosis in general in the body. There are works that, in particular, show that spironolactone reduces fibrosis in the heart. At the same time, it is known that the tendency to fibrosis is not local, but systemic – where there is more inflammation, there will certainly be fibrosis. And we see, of course, fibrotic changes in the “covide” in our patients. Therefore, we prescribed spironolactone as a drug for the prevention of this process.
Secondly, this drug blocks sex hormone receptors, in particular testosterone. Some published studies suggest that “high-testosterone” men suffer from “covid” more often and develop more severe fibrotic changes. Therefore, blocking these receptors for several weeks during COVID treatment may be useful in reducing the severity of complications. We are not talking about a longer intake, since male patients are unlikely to agree with a decrease in testosterone levels in the long term.
And perhaps the most important point. In almost all of our patients, we observed hypokalemia (a decrease in potassium levels. – Ed.). With coronavirus infection, potassium is intensely excreted from the body, and scientific articles even suggest that hypokalemia serves as the trigger for a cytokine storm. So spironolactone has a real chance to reduce the risk of this dangerous complication. But the main thing, in my opinion, is that lowering the level of potassium in the body is extremely harmful to the heart and triggers life-threatening rhythm disturbances, increasing the risk of sudden death. We, like all others, replenished potassium with droppers, but it was more effective to retain it in the body with the help of spironolactone.
Men certainly get worse than women; the elderly are heavier than the young; overweight people are heavier than overweight patientsPhoto: Ivan MAKEEV
WHEN PRESCRIBED PATIENTS
– Yana Arturovna, how many patients did you have on average?
– About 10 – 14 days. But someone and 50 days.
– Have you noticed signs by which it can be assumed that the disease in the person brought is likely to go the hard way?
– Such studies were carried out in the world, our clinical practice confirmed them. Men certainly get worse than women; the elderly are heavier than the young; overweight people are heavier than overweight patients. Men with a classic male type of baldness, a lot of facial hair, we can say brutal men get sick harder.
– Under what conditions did you discharge patients?
– We acted as close as possible to the recommendations Ministry of Health: so that the temperature for three days was not higher than 37.5 degrees; so that C-reactive protein (an indicator of inflammation) is lower than 10 mg / l, and saturation, that is, the level of oxygen in the blood, is higher than 96%.
“HEAD OF EPIDEMIOLOGY DEPARTMENT OF ITSELF WORKED AT SANPROPUSNIK”
– How often do you get sick doctors and nurses?
– In the first month no one got sick at all. We have a very powerful epidemiological service. The head of the sanitary-epidemiological department, a senior researcher, correctly organized the whole process, and for the first two weeks she personally worked in the sanitary inspection room at the exit from the “red zone” and helped doctors and nurses who were exhausted after the shift safely remove protective clothing.
Then both people’s fatigue and viral load accumulated. By the middle of the second month, sick people began to appear. There were no seriously ill patients. We treated part of the staff in our observation, part of it was treated at home. In total, 18 people were infected from the medical staff (less than 10%).
– Doctors take something for prevention? Vitamins C, D, Zinc?
– I saw the recommendations of American nutritionists, they speak out positively about taking zinc, melatonin and vitamin C. There were somewhat conflicting data on vitamin D. But we did not give any such recommendations to our employees. We have all the prevention was associated with minimizing contacts and other measures of epidemiological safety.
Physicians are the heroes of our time.“If you think that you are special and that a pandemic will not affect you, you are deeply mistaken,” listen to what the doctors who are fighting with coronavirus say
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Princeton University was expelled from the names of the faculty and the College name of the 28th U.S. President Woodrow Wilson because of racism. A statement published on the website of the institution.
The rector of the University Christopher Eisgruber reported that this decision was taken following a meeting of the Board of Trustees on June 26.
Travelers and confederates, whose monuments are demolished in the United States and Europe
“The Board of Trustees came to the conclusion that the racist views and politics of Wilson make him a name suitable for the Department of public and international Affairs and residential buildings of the College, faculty, students and graduates need to stand firmly against racism in all its forms,” said Eisgruber.
The rector added that this decision may seem harsh, because it is thanks to Wilson and the educational institution received the status of a leading research University. However, according to Eisgruber, faculty and the building of the University College it was named after the American politician “regardless of his racism or rather in spite of it”.
“Princeton is a part of America that is too often ignored or justified racism, allowing you to save system that diskriminerad blacks. When Derek Showin (police officer who used choke hold during the arrest of the deceased in the Minneapolis black Americans. — RBC) almost nine minutes of pushing with the knee on the neck of George Floyd, when witnesses noted its cruelty, it could be assumed that the system will ignore or justify his behavior, as was done in response to his previous complaints,” — said the rector of the University.
The authorities decided to dismantle the monument to Theodore Roosevelt in new York
George Floyd was killed in late may during the arrest police in the city of Minneapolis (Minnesota). Law enforcement officers suspected a black man in the reckoning of counterfeit checks. In the end, one of the officers pushed Floyd the knee on the neck. At the time of arrest he was screaming that he can’t breathe, but the policemen ignored his words. In the end, the 46-year-old man died in the hospital. Was subsequently dismissed four policemen, and one of them was accused of murder by negligence.
On the backdrop of the death of Floyd in a number of cities in the U.S. and Europe demonstrators demolished the monuments of those whom they consider involved in slavery and genocide. Among them — the monument to the discoverer Christopher Columbus, the only President of the Confederate States of America Jefferson Davis, the third US President Thomas Jefferson,the 18th US President Ulysses Grant, as well as the author of the US national anthem Francis Scott.
The monument to the head of the Russian Alaska proposed to remove from founded the city
The US President Donald trump was allowed to arrest anyone who damages or destroys sites. He also reminded that the perpetrators of the vandalism could face up to ten years in prison.
Subsequently, he signed the Executive decree on the protection of monuments, which provides for “long prison terms” for vandals.
– Has long been known that overweight people have lowered immunity, says head of the Department of endocrinology of the medical faculty Russian national research medical University. N. And. Pirogov Tatiana Demidova. Research and practice show that in these patients increases the risk of atherosclerosis sharply increases the risk of heart attacks, strokes and heart failure. Increased risk of endocrinological, oncological diseases, joint diseases, psychological disorders.
Epidemic COVID has added another item to the list of high threats to people who are overweight. It turned out that when infected with coronavirus patients with obesity more often require hospitalization, fall into the ICU, on the ventilator (artificial lung ventilation). Alas, is growing and the risk of death.
– If the original messages from China on the most severe cases COVID it was mainly about the older people with severe chronic diseases, according to the latest data from Europe and USA the risk group includes people with obesity – says Tatiana Demidova.
FACTS AND FIGURES
In what diseases most often develop complications due to coronavirus
90% of patients admitted with severe COVID-19 US hospitals, were the following comorbidities:
– hypertension — 49.7%,and
– obesity or 48.3%,
– chronic lung disease — 34,6%,
– diabetes type 2 diabetes was 28.3%,
– cardiovascular disease — 27,8%.
Thus, obesity is second among the States in which CouId be severe.
CORONAVIRUS, INFLUENZA, AND HIV, “LIKE” ADIPOSE TISSUE
Visceral adipose tissue, that is, one that is in the abdomen, is, in fact, highly individual body, experts explain. This body affects the immune, endocrine system and metabolism in the body as a whole.
– People who are overweight fat cells are much larger. So, is synthesized in much more of various hormones and inflammatory cells. Among them, including interleukin-6, interleukin-1, tumor necrosis factor, and others, – says Tatiana Demidova. Often in the body, there is a creeping inflammation.
At the same time observed that many viral infections and especially COVID-19 amplify the effects cytokines and lead to the extension of the generalization of inflammation. “It was proved that adipose tissue serves as a reservoir for some viruses, such as influenza, HIV and cytomegalovirus. Also, according to the latest data, it can be activated and coronavirus,” adds Demidov.
INSULATION NEEDS TO BE LONGER?
Studies have shown one more feature of coronavirus. As it turned out, he is able to spread rapidly in adipose tissue surrounding internal organs – lungs, liver, kidneys, heart, etc. because Of this, developing severe damage to these vital organs and people with excess weight, excess amount of adipose tissue increases the risk of death from multiple organ failure.
There is evidence that such patients are also unable to stay longer carriers of the virus, require longer hospital stay and isolation, said Tatyana Demidova.
AFTER INFECTION — DIABETES
There is evidence and that not less than one-third of patients hospitalized with COVID-19 in China, European countries and the United States, the infection resulted in damage of the pancreas. This was confirmed by elevated enzymes amylase and lipase, and glucose levels in the blood plasma.
– This is a very disturbing circumstance. Since we talking about high risk of developing diabetes type 2 diabetes in people with the original obesity after recovery from infection, says Dr. Demidov.
It is not excluded that after the break the pace of the epidemic COVID, we will see a worldwide surge in the incidence of diabetes, experts say.
So now, when the opportunity walks, sports, seasonal ripe fruits and vegetables rich in fiber, doctors suggest the obese individuals to exert their maximum effort for getting rid of really dangerous extra pounds.
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The objective will be the delivery of food to distribute among needy families.
The mayor of Cipolletti, Claudio Di Tella, will sign this Thursday, April 23, an agreement with the Faculty of Medicine de Cipolletti and the Fundación de Estudios Patagónicos a vonvenio that will aim to deliver foods to distribute among needy families.
The dean of the Faculty, authorities of the Foundation and its Food Bank will be present; and representatives of the Municipality.
The Faculty of Medicine of the National University of Rosario offered its facilities and all the human resources that are necessary to collaborate in the follow-up of patients suspected of having contracted the coronavirus. From that house of high studies they believe that the peak of the disease could occur between April and May.
The vice dean of the institution and infectious medicine doctor, Damián Lerman, maintained: “We have a human talent installed and a reserve of important volunteers that we make available to the provincial and municipal governments.”
Speaking to the program “The first in the morning” from The EightLerman said: “We have a call center to follow all patients who are discharged from hospitals or who are not hospitalized to prevent this from rebounding and not returning to the guards. This way we will avoid a problem that worries us and that is the saturation of the guards ”.
“We also offer simulation hospitals to be able to extract medical personnel. One of the big problems we have is that we have respirators, but we need people who are trained to use them. We are going in that direction, ”he added.
Regarding the perspectives for the advancement of the disease, the vice dean of Medicine was categorical: “We are waiting in hospitals, preparing ourselves for what we know may come. Cases are progressively increasing as expected. We prepare ourselves day by day, from the logistical and human point of view, to contribute what we can most “.
“We are careful with the times. The peak of the disease will arrive between April or May. But more than looking at when it will be, we are working on reinforcing all the facilities. When the peak of the disease comes, we want to have a health system that is as prepared as possible, ”he added.
Lerman pointed out that the Faculty must “have the seriousness of observing what is happening and preparing for what may come, without generating so much numerical estimation because that is also disturbing. Right now we need the population to be very calm, to comply with the measures that are being asked of them, and for our colleagues to be calm as well. We try not to give as many numbers but to prepare and see that the streets are empty and the people inside their homes. ”
“We want to convey calm. We are preparing. The Faculty is working. The province, the Municipality and the Nation also. But you have to have peace of mind. We have to inform ourselves through official channels, otherwise panic is generated in the population, “he added.
