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Earliest Evidence of Fire Use Discovered in African Cave

by Chief Editor June 17, 2026
written by Chief Editor

Evidence of Early Human Fire Use Pushed Back to 1.8 Million Years Ago

New archaeological evidence from South Africa’s Wonderwerk Cave suggests that early humans mastered the intentional use of fire as early as 1.8 million years ago. According to a study published in PLOS ONE, researchers identified burnt fossilized bones deep within the cave, marking a significant shift from previous estimates of one million years ago. Dr. Liora Kolska Horwitz of the Hebrew University of Jerusalem and Prof. Michael Chazan of the University of Toronto led the project, utilizing a new luminescence-based detection method to verify the findings.

How researchers identified the ancient fire

How researchers identified the ancient fire

The research team developed a non-invasive technique to detect heat-induced changes in fossilized remains. According to Dr. Kolska Horwitz, this method involves applying a specific substance to bone samples and observing them under ultraviolet (UV) light. Burnt areas glow white, providing a clear indicator of fire exposure. This approach replaces older, destructive methods that required grinding down bone fragments for chemical analysis. By making the process quicker and cheaper, the team expects this technique to be adopted at other prehistoric sites worldwide to track the evolution of fire usage.

Why this discovery changes the timeline of human evolution

The location of the fire remains provides the strongest evidence for intentional human activity rather than natural causes. Dr. Kolska Horwitz notes that the burnt materials were found at least 30 meters from the cave entrance, ruling out the possibility of a wildfire drifting inside. Furthermore, the researchers found no evidence of spontaneous combustion, such as guano deposits, which can ignite under specific chemical conditions. This suggests that early hominins, likely a form of Homo erectus, purposefully brought fire into their living space nearly 800,000 years earlier than previously documented at this site.

Did you know?
Wonderwerk Cave is considered one of the most significant archaeological sites in the world. It provides a continuous record of human occupation spanning approximately two million years, ranging from the early Oldowan stone tool culture to 20th-century history.

Comparing the 1.8 million-year-old evidence to previous findings

Fire’s Discovery – How Flames Transformed Prehistoric Life 1.42 million years ago | Boring Sapien

The current study builds on a 2012 analysis that dated fire usage in the cave to one million years ago. The new findings are based on samples taken from a deeper sedimentary layer, separated from the previous site by roughly 80 centimeters of earth. The dating was verified using two primary techniques: paleomagnetic dating, which tracks shifts in Earth’s magnetic field, and cosmogenic burial dating, which measures the decay of cosmic radiation signatures in quartz grains. While the 2012 findings provided a major milestone, this recent study effectively doubles the timeline for sustained fire use at the site.

What happens next in the Wonderwerk Cave project?

What happens next in the Wonderwerk Cave project?

The research team is now shifting its focus to the deepest levels of the cave, which date back two million years. While the current 1.8 million-year-old threshold is a breakthrough, Dr. Kolska Horwitz indicated that the “big question” is whether evidence of fire exists at the very base of the site’s occupation. Because no human remains have been discovered in the cave, identifying the specific hominin species responsible for these fires remains a primary goal for future excavations, with fieldwork scheduled to continue.

Frequently Asked Questions

Could these fires have been caused by lightning?
No. According to the study, the fire remains were discovered 30 meters deep inside the cave, making it impossible for a natural wildfire or lightning strike to have reached that area.

What kind of humans lived in the cave?
While no human fossils have been recovered, Dr. Kolska Horwitz suggests that early Homo erectus populations are the most likely inhabitants given the timeline and regional context.

How does the new luminescence method work?
The method detects burnt bone by applying a chemical agent and examining the surface under UV light. Burnt areas emit a distinct white glow, allowing researchers to identify fire use without destroying the fossil.


Do you have questions about human evolution or the tools used in modern archaeology? Join the discussion in the comments section below, or explore our archives for more on the origins of early human technology.

June 17, 2026 0 comments
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Health

Hebrew University study shows how your body’s stem cells fight Salmonella

by Chief Editor May 17, 2026
written by Chief Editor

The Gut’s Secret Weapon: Beyond Simple Regeneration

For decades, we viewed intestinal stem cells as the “maintenance crew” of the digestive tract—essential for repairing the lining of the gut and replacing old cells. However, groundbreaking research from the Hebrew University of Jerusalem and the Weizmann Institute of Science has flipped this narrative on its head.

It turns out these stem cells aren’t just passive builders; they are active combatants. A recent study published in Nature Immunology reveals that gut stem cells can directly sense the presence of dangerous pathogens, specifically Salmonella enterica, and pivot their entire biological purpose to defend the body.

Did you know? Most Salmonella infections resolve within a few days without medical intervention. This discovery explains why: your gut stem cells are essentially “shape-shifting” into antimicrobial warriors to clear the infection.

When these stem cells detect an invasion, they trigger a multiprotein complex known as an inflammasome. This trigger causes the stem cells to rapidly differentiate into specialized Paneth cells. These antimicrobial powerhouses secrete molecules that limit bacterial persistence, effectively starving the infection and protecting the intestinal barrier from total collapse.

From Salmonella Defense to Crohn’s Disease: The Missing Link?

While the ability to fight off foodborne illness is a biological win, the implications of this research extend far beyond acute infections. The research team, led by PhD student Sacha Lebon and supervised by Dr. Matan Hofree and Dr. Moshe Biton, uncovered a startling connection to chronic illness.

View this post on Instagram about Salmonella Defense, Sacha Lebon
From Instagram — related to Salmonella Defense, Sacha Lebon

The study found that the specific “stem cell signature” activated during a Salmonella infection is also highly enriched in the intestinal stem cells of patients suffering from Crohn’s disease.

This suggests that in patients with Inflammatory Bowel Disease (IBD), the body’s first line of defense—the epithelial barrier—might be stuck in a state of perpetual “alarm.” Instead of a temporary response to a pathogen, the immune system may be triggering this stem-cell-driven defense mechanism inappropriately, leading to the chronic inflammation characteristic of Crohn’s.

Future Frontiers: How This Discovery Will Change Medicine

We are entering an era of “precision immunology.” By understanding the exact pathway from stem cell to Paneth cell, scientists can begin to manipulate these processes to treat diseases that were previously considered unmanageable.

Future Frontiers: How This Discovery Will Change Medicine
Hebrew University Crohn

Targeted Therapies for Inflammatory Bowel Disease (IBD)

Current IBD treatments often rely on broad immunosuppressants that leave patients vulnerable to other infections. Future trends point toward pathway-specific modulation. If we can “dial down” the overactive inflammasome response in Crohn’s patients without disabling their overall immunity, we could potentially halt the progression of the disease.

The Rise of “Bio-Mimetic” Gut Defense

The use of organoids—miniature, lab-grown versions of organs—was central to this study. In the future, we may see the development of “smart” probiotics or bio-engineered cellular therapies that mimic the Paneth cell response, helping patients with compromised gut linings fight off infections without relying solely on antibiotics.

The Rise of "Bio-Mimetic" Gut Defense
Hebrew University Mount Scopus campus
Pro Tip: To support your gut’s natural mucosal barrier, focus on a diet rich in prebiotic fibers and fermented foods. While stem cells do the heavy lifting during infection, a healthy microbiome reduces the “stress” these cells face daily.

Rethinking the Antibiotic Paradigm

As antibiotic resistance becomes a global crisis, the medical community is shifting toward host-directed therapies. Instead of trying to kill the bacteria directly with chemicals, the future of medicine may lie in enhancing the body’s intrinsic ability to differentiate antimicrobial cells. By “priming” the gut’s own stem cell response, we could treat infections with far fewer side effects than traditional drugs.

Rethinking the Antibiotic Paradigm
Salmonella bacteria under microscope

Frequently Asked Questions

What are intestinal stem cells?
They are undifferentiated cells located in the crypts of the intestinal lining that normally divide to replace the cells shed during digestion.

How do stem cells fight Salmonella?
They use an inflammasome-driven process to transform into antimicrobial Paneth cells, which secrete substances that kill or limit the growth of the bacteria.

Does this mean Crohn’s disease is caused by Salmonella?
Not necessarily. It means that the mechanism the body uses to fight Salmonella is similarly active in Crohn’s patients, suggesting a shared biological pathway in the body’s immune response.

Where can I read the full study?
The research was published in the journal Nature Immunology.

Join the Conversation

Do you think the future of medicine lies in enhancing our own biological defenses rather than relying on pharmaceuticals? We want to hear your thoughts!

Leave a comment below or subscribe to our health innovation newsletter for more deep dives into the future of medicine.

May 17, 2026 0 comments
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