Stanford Medicine researchers have identified a primary driver of biological aging: the failure of tissue-resident macrophages to clear senescent, or “zombie,” neutrophils from the body. According to a study published July 16 in Science, blocking a specific pro-inflammatory receptor, EP2, on these immune cells rejuvenated organ function and reduced age-related frailty in mice. This discovery … Read more
Research from the University of Virginia (UVA) Comprehensive Cancer Center indicates that a buildup of bile acids, triggered by an unhealthy gut microbiome, can drive hormone receptor-positive (HR+) breast cancer to metastasize to other organs, particularly the lungs. According to Melanie Rutkowski, PhD, this mechanism suggests that FDA-approved bile acid sequestrants or microbiome replenishment could … Read more
A multidisciplinary panel of 60 specialists has released the 2025 edition of the Chinese consensus on the diagnosis and treatment of prolactinomas, published in the Chinese Neurosurgical Journal on June 8, 2026. This evidence-based framework standardizes care across endocrinology, neurosurgery, and radiology to improve early detection and patient outcomes for the most common hormone-secreting pituitary … Read more
Women who have used hormonal birth control or menopausal hormone therapy (MHT) show structural brain differences associated with healthier aging, according to research published in the journal NeuroImage. A study of 459 women aged 65 to 80 found that lifetime exposure to these hormones correlates with greater gray matter volume and cortical thickness in brain … Read more
Scientists are increasingly viewing gut microbes as active participants in hormone-driven cancers, moving beyond the traditional “estrobolome” model to define a bidirectional endocrine-microbiome axis. According to a review published in the journal npj Biofilms and Microbiomes, researchers are investigating how these microbial communities influence the metabolism of estrogen and contribute to the development of breast … Read more
Exposure to glyphosate, the active ingredient in many weed killers, is linked to changes in hormones that support pregnancy and fetal development, according to a University of Michigan School of Public Health study. Researchers observed shifts in estriol, thyroid hormones, and corticotropin-releasing hormone among 752 pregnant women in Puerto Rico. How does glyphosate exposure affect … Read more
Nearly 4 in 10 patients with type 2 diabetes stop their GLP-1 medication within the first year of treatment, according to research presented at the Endocrine Society’s annual meeting, ENDO 2026. While discontinuation rates climb to nearly 6 in 10 by the end of two years, the data reveals a high frequency of patients restarting … Read more
Early-life exposure to the common plasticizer di-(2-ethylhexyl) phthalate (DEHP) is linked to increased anxiety-like behavior in adulthood, according to research presented at the Endocrine Society’s annual meeting, ENDO 2026. Scientists from the University of Buenos Aires School of Medicine found that prenatal and postnatal exposure to the chemical in rats caused lasting behavioral changes, including … Read more
Solid-organ transplant recipients face a significantly higher risk of mortality if they develop diabetes, according to a comprehensive analysis presented at ENDO 2026, the Endocrine Society’s annual meeting. Researchers analyzed data from over 800,000 U.S. patients who underwent transplants between 2003 and 2021, finding that both pre-existing and post-surgery diabetes consistently reduced long-term survival rates … Read more
New Clinical Guidelines Aim to Reduce Unnecessary Testing for Precocious Puberty The Endocrine Society has released updated clinical practice guidelines for managing central precocious puberty, emphasizing that not all children showing early signs of development require medical intervention. According to the guidelines, published in The Journal of Clinical Endocrinology & Metabolism, clinicians should prioritize observation … Read more