Covid-19 defense goes wrong: immune thrombosis triggers severe course

There are still many unanswered questions about the corona virus. One of them is why the Covid-19 disease caused by the virus is so severe in some of the infected that it can even lead to death. Researchers may now have found a new answer to this.

A team from the Friedrich-Alexander University Erlangen-Nürnberg (FAU) is believesthat a certain mechanism of the immune system could play a role in whether Covid-19 is severe or mild in patients. The researchers led by Moritz Leppkes from the Erlangen University Medical Center examined Covid 19 patients who had to be treated in the intensive care unit and found that they had a higher number of certain immune cells, so-called neutrophil granulocytes. In some people, an infection with the coronavirus seems to cause the production of this type of white blood cell to be strongly activated.

According to the researchers, these granylocytes clump together and form mesh-like structures in the blood vessels. Actually, these networks, which are medically connected to NET (Neutrophil Extracellular Traps), capture intruders such as bacteria and viruses and fight them in a targeted manner. This type of special immune response was only discovered in 2004. In the case of Covid-19, however, it could happen more often that the nets quickly clog the fine blood vessels in the lungs and other parts of the body.

These clogged blood vessels cause gas exchange in the lungs or other tissue to come to a standstill and the body can no longer be adequately supplied with oxygen. It comes to a life-threatening condition. Since the process has many similarities with other thromoboses, the researchers speak in the journal “The Lancet” published study from an immune thrombosis.

This type of thrombosis has not been considered in previous treatment in severe Covid 19 cases. But like that “Medical journal“reports, the researchers’ findings could have an impact on future therapy:” The researchers see a treatment approach for severe Covid 19 cases in inhibiting the agglomeration of neutrophils and preventing the increased formation of NETs. ” For example, the drugs dexamethasone or heparin help. “Heparin is already used in Covid-19 patients to prevent thrombosis. However, it is possible that the standard dose is not sufficient to prevent thrombosis by the NET, “said the journal.

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From COVID-19 to Tick-Borne, Why Did a ‘Unique’ Disease Appear in China?

Jakarta

China is back in the world spotlight. Because, recently China reported a case of viral infection caused by tick bites, also known as tick-borne.

Quoted from Firstpost, the virus which has infected at least 60 people and killed 7 victims has been identified as the cause of the disease severe fever with thrombocytopenia syndrome (SFTS).

Before the SFTS, China had also reported several cases of disease outbreaks, such as bubonic plague, G4 virus, and swine flu corona virus COVID-19 which to this day is still going on and has become a pandemic in the world.

So why do so many ‘unique’ diseases arise in China?

According to an infectious tropic disease expert from the Faculty of Medicine, University of Indonesia (FKUI), Dr. Adityo Susilo, SpPD-KPTI, there may be several factors that cause so many ‘unique’ or rarely heard diseases that often appear in China. One of them is from the factor lifestyle community in that country.

“I don’t know exactly, but what is certain is that the population is large, and more or less is also related to the lifestyle of environmental cleanliness and others. So I also don’t know why China? We can’t stigmatize too,” said Dr. Adityo to detikcom, Sunday (9/8/2020).

“But logically, China is densely populated, then the cleanliness is lacking and in the end, maybe exposure to disease if yesterday was COVID, for example, an extreme diet. If this is not related to diet, but perhaps hygiene and contact with animals,” he explained.

Besides that, Dr. Adityo also explained that the case was initially reported tick-borne This is in a rural area in China, which is probably a lot of farms in the area. Especially in a study in 2015, several species of fleas that cause this SFTS live in sheep, cattle, dogs and cats.

Even so, Dr. Adityo expressed his admiration for China because they have a pretty good ability to diagnose a disease.

“It means that he (China) on the one hand is densely populated and is a bit dirty, but on the other hand he can diagnose diseases in quotation marks that are rare and strange,” he said.

Watch Video “The Tick-Borne Virus Facts That Shook China
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Is THAT the reason people die from Covid-19?

Why do some have such a difficult course?

Even if the pandemic has been with us for many months, there are still unanswered questions about that Coronavirus. One of them is why exactly the Covid-19 disease caused by the virus is so severe in some of the infected that it can even lead to death. Researchers may now have found a new answer to this.

What is an immune thrombosis?

A team from the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) believes that the immune system could play a role in whether the disease is severe. The researchers examined Covid-19 patients who had to be treated in the intensive care unit and found that they had a higher number of certain immune cells, the neutrophils. So the coronavirus seems to activate this type of white blood cell a lot.

This thrombosis has not been considered in the previous treatment of severe Covid 19 cases. But as the “Ärzteblatt” reports, the researchers’ findings could have an impact on future therapy: “The researchers see a treatment approach for severe COVID-19 cases in inhibiting the agglomeration of neutrophils and the increased formation of NETs prevent.” The drugs dexamethasone or heparin, for example, could help. “Heparin is already being used in COVID-19 patients to prevent thrombosis. However, it is possible that the standard dose is not sufficient to prevent thrombosis by the NET.”

Video Playlist: Everything You Need To Know About Coronavirus Now

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Fridman’s plan ends them in the villages

Related news

The arrival of Mikhail Fridman to Dia has caused many changes in the chain, especially regarding the franchise business model that has put many of its oldest franchisees on the warpath. Many of them have been converted, others have closed and even one banner will disappear this year: Every Day.

During the first half of this year, 40 Dia stores were closed in Spain (25 franchises and 15 of their own) and as part of the strategic closure announced for this type of franchise, a total of 78 Every Dia stores closed. In addition, 85 franchises have become their own in Spain, including 18 Clarel stores.

Last September, Dia decided to close one of its franchised brands, Cada Dia. The closure of the 201 stores is being carried out according to the agreement with each of the establishments. The company estimates that throughout 2020 the banner will disappear permanently, after the end of the longest contracts.

This format was focused on smaller populations, especially rural ones, so that the franchisee, without having the need to transform the establishment into a Dia store, can offer brand products. In fact, in some towns it was the only supermarket that existed.

The cessation of the activity of Cada Dia is part of the simplification and unification of the formats and lines of activity of the group, as part of its business strategy and the new transformation plan of the company, which will take more force during the second semester of the year after registering losses of 187 million until June.

Transformation plan

“In the second semester we will continue with the transformation plan that is based on the pillars of improvement of the commercial proposal and the franchise model supported by a continuous improvement of operational efficiencies”, explained the president of Dia, Stephan DuCharme, during the presentation of results.

Actually, Dia has 4,041 stores in Spain, of which 1,477 are franchises, almost 300 less than a year ago. As of June 30, 2019, the company had 4,369 stores in Spain, of which 1,863 are franchisees.

From Dia they remember that the news of the new franchise model they have already been implemented in 470 locations in Spain during the first half of 2020, with the goal of reaching 350 locations in the second half of 2020. According to Dia, it is an “improved model based on incentives and focused on the consumer, with key benefits for the business, including the “payment after sale”.

However, assortment changes, price increases or product shortages in certain stores are some of the issues that have put the franchisees on the warpath of the school during the last year.

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Covid-19: Sweden complains of WHO “error”, which indicates it as a country with “accelerated transmission” | Coronavirus

Sweden did not like to be included in a list of 11 countries in which “accelerated transmission” of SARS-CoV-2 infections “not only led to a significant resurgence, but, if left unattended, will again lead to health on the verge of rupture in Europe, ”according to the World Health Organization (WHO).

Sweden is mentioned alongside Armenia, Moldova, North Macedonia, Azerbaijan, Kazakhstan, Albania, Bosnia and Herzegovina, Kyrgyzstan, Ukraine and Kosovo.

The person responsible for monitoring the pandemic in Sweden, Anders Tegnell, classified the inclusion on the list as a “complete error” on the part of WHO, who did not take into account, he argued, that the number of tests has increased a lot, and this has also led to the detection greater number of infections. The Swedish healthcare system, he stressed, has never been on the brink of rupture and still is not.

WHO had previously come to speak of Sweden as a model for countries that were beginning to get out of confinement. Emergency expert Mike Ryan said at the end of April that “if we think we have to have a new normal, Sweden can be a model if we want to return to a society without confinement”.

Hans Henri Kluge, the WHO’s regional director for Europe, has now joined Sweden with countries that “are at risk of resurgence while adjusting measures.”

Anders Tegnell underlined to Swedish public radio that “the number of cases has increased since we started testing a lot more, last week”, and added: “we can look at all the other parameters that we measure, which is how many serious cases we have, and are decreasing ”.

The Swedish approach has led to much criticism, some accepted by Tegnell, who says that more measures should have been taken to protect the elderly. Along with the criticisms (the American daily New York Times said recently that the country is experiencing what it is like to be a “pariah state”), Stockholm’s policy has also been taken as an example by those who refuse isolation and confinement measures.

The country has the highest death rates per capita de covid-19, but Tegnell and other officials have argued that comparisons of both the number of infected and dead can only be made at the end of the pandemic.

According to Johns Hopkins University (USA), which compiles data from health authorities around the world, Sweden recorded 65,000 infections and 5280 deaths (alongside, Norway recorded 8,828 infections and 249 deaths).

There are several countries that started with good control, such as Israel, but where there are outbreaks and a significant increase in cases. In other countries, the WHO says that although there are outbreaks, they are being controlled, as in Germany or Italy.

The Swedish Government had promised an inquiry into the management of the pandemic when it ended, but announced that it would start doing so before that.

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The United Nations warns of a global mental health crisis caused by the Covid-19 pandemic

LONDON (Reuters) – A mental health crisis looms on the horizon as millions and millions of people around the world are trapped in death and disease, leaving them isolated, impoverished and worried by the Covid-19 pandemic, UN health experts said on Thursday.

Two health workers cry during the memorial of a colleague who died of an infection with the Corona virus in Spain on April 13, 2020. Photo: Susanna Pera – Reuters.

“Isolation, fear, confusion, and economic instability all cause or may be the cause of a psychological crisis,” said Devora Kestel, director of the World Health Organization’s mental health department.

During the presentation of a report and the presentation of a United Nations guideline on Covid-19 and mental health, Kestel suggested increasing the number and severity of mental illnesses and called on governments to place this matter “at the center and center” of their pandemic control plans.

“The mental health and well-being of entire societies are severely affected by this crisis, which is a priority that needs to be addressed urgently,” she told reporters.

The report highlights several groups and sectors of society that are at risk of psychological problems, and include children and youth separated from their friends and schools, as well as health-care workers who are witnessing the infection and death of thousands of coronaviruses.

Already emerging studies and statistics show the influence of Covid-19 on mental and mental health globally. Psychologists say children suffer from anxiety, and depression and stress have increased in several countries.

Domestic violence is increasing, and health workers are talking about the increasing need for psychological support.

Reuters last week reported what was reported in interviews with doctors and nurses in the United States who said they or their colleagues had a combination of panic, anxiety, depression, numbness, irritability, restlessness and nightmares.

Outside the health sector, the WHO report says many are concerned about the immediate health consequences and consequences of isolation, while others fear infection, death and the loss of family members.

Millions face economic instability, they lost or face the risk of losing income and livelihoods, the report added. Some also feel anxious and frustrated about the future, as there is a lot of misinformation and rumors about the pandemic and severe foggy about its duration.

The report listed action points that decision-makers can use to “reduce the extreme suffering of hundreds of millions and reduce the long-term social and economic consequences for society”.

These points include addressing the problem of the lack of chronic investments in psychological services and the provision of an “emergency mental health service” via remote healers such as providing telephone consultations to frontline workers to confront the pandemic in the health sector and working proactively with those who suffer from depression and anxiety and those facing the risk of domestic violence and poverty Severe.

Marwa Salam Prepared for the Arab Bulletin – Edit Abu Amal Al Saud

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Corona worldwide: Czech Republic removes restrictions – politics

The Czech government has been around for weeks Exit restrictions surprisingly lifted. This will apply from Friday, said Health Minister Adam Vojtech late Thursday evening in Prague. Since March 16, citizens have only been allowed to go to work, to go shopping, to the doctor or to go for walks in green areas. The minority cabinet thus reacted to the current decision of a court in Prague, which had declared the previous measures illegal for formal reasons. “We respect this verdict,” said Vojtech of the populist ANO party, head of government and multi-billionaire Andrej Babis. Meetings with more than ten participants were prohibited.

The lifting of the exit ban for Czech citizens is also lifted. Upon return, they must submit a negative test for the coronavirus or in a 14-day quarantine. According to the Ministry of the Interior, the extensive freeze on entry remains – with new exceptions for business people from EU countries. The cabinet also decided to make it easier for Czech commuters who work in Germany or Austria. You can now cross the border every day if you can submit a new, current test for the corona virus every 14 days.

Indonesia bans domestic air traffic

The Indonesian government has now banned trips to the festival of fasting. The Islamic month of fasting Ramadan ends on May 23 with the festival Eid al-Fitr. Last year, around 15 million Muslims from the Jakarta capital region drove home. Such a wave of travel should now be prevented because of the risk of infection.

For this reason Indonesia now bans all domestic air traffic. The ban applies from April 24 to June 1 and includes both scheduled flights and private jets. President Joko Widodo is turning around. At first he had given permission for the festivities, but with the condition that the believers would then have to isolate themselves at home. Afterwards, he said that mass transport would be completely prohibited. Islamic scholars had previously said that such trips during a pandemic were “haram”, that is, prohibited. With more than 260 million inhabitants, the island nation is the most populous Muslim country in the world. So far, there are 7135 infections in Indonesia with the pathogen Sars-CoV-2, which can trigger the lung disease Covid-19. 616 people died.

Trump suspends green card issuance for 60 days

US President Donald Trump has signed an order that will make immigration to the United States much more difficult in the wake of the Corona crisis. The order will “ensure that unemployed Americans will be first in line when our economy reopens,” Trump said at a White House press conference. Many US citizens have lost their jobs as a result of the pandemic.

The suspension essentially applies to migrants who apply for a permanent green card residence permit. A green card is a document of identification from the USA, which usually includes a permanent residence and work permit for ten years. There are different ways to get them, for example through a job or by drawing lots. Around a million people received a green card last year. The green card is suspended for 60 days, but there are a few exceptions. This includes immigrants who are already in the country, those with valid immigrant visas, doctors and nurses, as well as the spouses and unmarried children of US citizens. Temporary residence permits are not affected by the changes.

Two domestic cats are infected in the state of New York

For the first time, the authorities in the United States have one Covid-19 disease in pets proven. According to the US Centers for Disease Control and Prevention (CDC) are in the state of New York two domestic cats tested positive for the virus been. The animals had slight breathing problems and would probably recover, the agency said.

It is believed that they have become infected in people in their households or in the neighborhood. Experts suspect that some animal species are infected with the corona virus in humans, but cannot transmit it back to humans. There is no evidence that pets played a role in the spread of the virus in the United Statesthe health authority said. Experts recommend that pet owners suffering from Covid-19 avoid contact with pets as much as possible and wear a mouthguard when feeding them.

Müller wants to help developing countries with more than four billion euros

Development Minister Gerd Müller demands another three billion euros from the federal budget to combat corona in the third world. The immediate program planned so far from the development budget for more than one billion euros “alone will not be enough to counter the global crisis,” says the CSU politician to the newspapers of the “Funke Mediengruppe”. There is “a further immediate need of three billion euros for emergency aid for basic services”, especially in refugee regions. He had registered these funds for the supplementary budget for 2020.

The pandemic is developing into a global health, food and economic crisis in the immediate vicinity of the European Union, warns Müller. “We have to prevent hospitals and then entire states from collapsing. The consequences would be dramatic: hunger, unrest and ultimately uncontrollable refugee movements.” The aid concept from the development ministry, which is available to the newspapers, provides for investments of 800 million euros each in health care and food security in particularly poor countries. The provision of protective clothing and mobile hand washing systems is just as much a part of this as investments in water supply and the distribution of food.

Brazil’s health minister plans to present “Corona exit plan”

Corona virus updates – twice a day via email or push message

All reports on the current situation in Germany and worldwide as well as the most important news of the day – twice a day with SZ Espresso. Our Newsletter brings you up to date in the morning and evening. Free registration: sz.de/espresso. In our News app (download here) you can also use the espresso or breaking news Subscribe as a push message.

The new Brazilian Minister of Health Nelson Teich has announced a relaxation of restrictions on public life in the Corona crisis. The government would present a corresponding policy for cities and states within a week. “It is impossible for a country to survive a year, a year and a half if it stands still,” said Teich. “Social distancing is a natural measure and logical at the beginning, but it cannot be used without an exit plan.” Even if the number of people infected with corona in his country were 100 times higher than announced by the Ministry of Health, that would only be two percent of the population.

On the critical situation in the city of Manaus pond did not die in the Amazon region. The health system there has already collapsed and a refrigerated container for storing corpses has been set up in front of a large hospital. President Jair Bolsonaro had appointed the oncologist last Thursday to succeed Luiz Henrique Mandetta. The latter was dismissed in the dispute over the correct handling of the corona virus.

Four days curfew in Turkey

In more than 30 Turkish cities and provinces, including in Istanbul and Ankara, is open in the night from Wednesday to Thursday extensive exit ban came into force. The government had curfewed twice over the weekend because of the corona pandemic. The current ban covers four days: from Thursday, which is a national holiday in Turkey, to the Friday bridging day on which Ramadan begins in the evening and until Sunday evening.

Most people who are younger than 20 or older than 65 and chronically ill have previously been banned from going out. Some shopping opportunities should remain open on Thursday and Friday at least half a day. In addition, clinics, pharmacies, bakeries and other service providers classified as important may work on weekends. Fasting in Ramadan will also be prohibited in large groups, as the Home Office ordered on Wednesday. In addition, the drummers who move around the houses at night to wake up the faithful before sunrise are not allowed to collect donations at front doors.

Health Minister Fahrettin Koca said Wednesday night that the virus was “under control”. Almost 3,100 new infections were registered – not as little as since the beginning of April, the day before there were more than 4,600. In total, almost 99,000 corona infections were reported in Turkey by Wednesday evening, according to Johns Hopkins University figures, and there were nearly 2,400 deaths.

Army to help fight pandemic in South Africa

In the fight against the corona virus the South African government is calling on tens of thousands of soldiers. A letter to Parliament confirmed by the Ministry of Defense indicates that 75,000 soldiers should be active by the end of June. President Cyril Ramaphosa justifies this by maintaining order and border controls. At the same time, he announced in a TV speech to the nation a billion-dollar aid package in the amount of the equivalent of 25 billion euros – about ten percent of the gross domestic product. In South Africa, more than 3,400 cases of Covid-19 have been confirmed and at least 58 people have died.

Israel suspends cell phone surveillance for quarantine control

A parliamentary committee in Israel stops the further Use of cell phone data to monitor quarantine requirements. “The big damage to privacy outweighs the benefits,” Ayelet Shaked of the Foreign and Defense Committee wrote on Twitter. The government initially implemented the measures for a month. The consent of Parliament should be necessary for an extension.

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Coronavirus News: Meuse – No normal vacation season – politics

Foreign Minister Heiko Maas (SPD) assumes that normal summer vacation will be canceled this year due to the Corona crisis. “There won’t be a normal vacation season this summer,” he said in Berlin. “That would not be responsible.”

In general, the main focus in all countries is currently on the containment of the corona virus, said Maas. Also in the European Schengen area, which normally no longer has internal border controls, there are still many entry and exit bans as well as quarantine measures “that do not make a vacation worthy of the name vacation possible”. The minister said that there was an ongoing review of whether travel restrictions could be lifted gradually, “and I cannot see any signs of this at the moment.” European and international coordination is important on the subject.

NRW: Services should be possible again from May 1st

In North Rhine-Westphalia, various religious communities are supposed to be able to hold worship services again from May 1st. The state government said in a press release. “The state government of North Rhine-Westphalia has never been the only country to prohibit a joint worship service, but has considered it sufficient to accept the churches and religious communities in declarations of voluntary commitment to waive religious meetings,” it says. The communities had complied with these commitments “in an impressive way”.

After working out appropriate security and distance concepts, the meetings should now be possible again next month. “Jewish communities have refrained from celebrating the Passover together and Christians have given up the big services at the festivities from Maundy Thursday to Easter. For their part, the Muslims have declared that they will celebrate the start of Ramadan without Friday prayers and that Ramadan, with its evening meetings for breaking the fast, will be different than in all years before “, is quoted by NRW Prime Minister Armin Laschet, who thanked the faithful for their understanding. Freedom of religion is an important fundamental right of our constitution, according to the CDU politician.

World Medical President Montgomery criticizes mask requirement

Frank Ulrich Montgomery criticizes the planned nationwide mask requirement. “Anyone who wears a mask will surely think he is forgetting the minimum distance that is decisive,” said Montgomery of Düsseldorf Rheinische Post. Masks could be dangerous if used improperly.

A virus is concentrated in the fabric, when you lose weight you touch the skin of your face, you can hardly get infected faster, Montgomery said. A legal mask requirement can only exist for real protective masks, a requirement for scarves or shawls is “ridiculous”. At the same time, he pointed out that all “really effective masks” are still needed for medical staff, nurses and those at risk.

Masks are mandatory in all federal states

In Germany nationwide one in the coming days Mask requirement enter into force to contain the coronavirus. Bremen was the last federal state to announce a corresponding decision on Wednesday. The regulation should be adopted on Friday and apply from Monday to local public transport and shopping in shops, as a spokesman for the state government said.

Prime Minister of North Rhine-Westphalia Armin Laschet (CDU) had previously rejected an obligation to wear mouth-nose protection and opted for voluntary action. Prime Minister of Lower Saxony Stephan Weil had criticized the advance of some countries in the mask requirement. “Yes, it’s annoying to me, I’m honest. And that’s because we only sat together five days ago,” said Weil on Tuesday evening at “Markus Lanz”. There is “no significant new evidence in this regard, except, of course, that there is some public pressure.” Thuringia’s Prime Minister argued similarly Bodo Ramelow (left) on the ARD-Extra program: “What surprises me is that the colleagues who spoke against it on Wednesday were the first to start introducing it.”

Chancellor Angela Merkel and the Prime Ministers only agreed last week to strongly recommend wearing so-called everyday masks on buses and trains as well as in retail.

Corona virus updates – twice a day via email or push message

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Grand coalition increases short-time work allowance

The leaders of Union and SPD have one Increase in short-time work benefits suitable. In view of the Corona crisis, it should be increased from 60 to up to 80 percent for childless employees, depending on the period of reference, and from 67 to up to 87 percent for employees with children.

The new regulation, which the party and parliamentary group leaders of the CDU, CSU and SPD have agreed on, provides in detail that the previous short-time allowance rates apply in the first three months. From the 4th month 70 or 77 percent of the loss of wages would be paid, from the 7th month 80 or 87 percent.

The coalition also agreed to generally reduce the value added tax on food in restaurants to seven percent. So far, a rate of 19 percent is due for food consumed in restaurants, cafes or pubs, only if the food is taken with you, seven percent applies. Aid was also decided for needy pupils who do not have sufficient equipment for digital instruction at home.

Coronavirus: Your opinion on the loosening:Readers’ discussion

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Coronavirus enters through nose

MDC institute refers to study
Researchers find a gateway for coronavirus

It was already known that the corona virus is highly contagious and is transmitted via droplets. But now researchers have found out which part of the body is most likely to enter the body.

According to a study, special cells in the nose are the most likely entry points for the new coronavirus. Several research teams had examined cells from the lungs, nose, eyes, intestines, heart, kidneys and liver, as reported by the Max Delbrück Center for Molecular Medicine (MDC) in Berlin. They wanted to find out which cells contain the two most important entry proteins ACE2 and TMPRSS2, which the virus uses for the infection.

“We then showed that of all cells, the mucus-producing goblet cells and cilia in the nose have the highest concentrations of these two proteins,” explained lead author Waradon Sungnak of the Wellcome Sanger Institute. “This makes these cells the most likely primary route of infection for the virus.” The Max Delbrück Center also reported that the two most important entry proteins are also found in the corneal cells of the eye and in the intestinal mucosa.

This indicates a further possible route of infection via the eye or the tear glands. The MDC writes rather cautiously that there is also potential for transmission via feces and ingestion by mouth. The research teams have published their results in the journal “Nature Medicine”.

Various institutes were involved in the study, including the Wellcome Sanger Institute, the University Hospital Groningen and the University of Cote d’Azur, as well as the Human Cell Atlas Lung Biological Network.

According to the MDC message, up to 20 percent of corona patients suffer damage to the heart muscle up to heart failure. The docking station for the corona virus was also found there. However, it is still unclear whether the virus itself causes damage to the heart or whether it is secondary effects.

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LIVE-TICKER Coronavirus – Daimler reports extreme drop in profits

April 23, 2020 – 7:50 a.m.

In the video: These are the changes to the corona measures

How important are caregivers? Very much – the corona crisis shows this once again. Politicians now want to make this clear in their money bags too. And why wearing face masks can really mean stress. In the live ticker you will find all important information and developments.

Here you will find an overview of the changed measures of the federal states and everything from A to Z you need to know about the corona virus.

TVNOW documentary: Zero Hour – Race with the Virus

How do we defeat Corona? See the TVNOW document: “Zero Hour – Race with the Corona Virus” (part 2)

+++ LIVE-TICKER +++

7:45 am – Almost a fifth of German companies are planning to cut jobs

According to the ifo Institute, almost a fifth of German companies are planning to cut jobs in the wake of the crisis. 18 percent of the companies wanted to fire employees or not to extend fixed-term contracts, the institute said, citing its April survey. 46 percent of the companies wanted to postpone investments, almost 50 percent would do short-time work.

7:35 a.m. – Daimler reports extreme drop in profits

  DEU Germany, Baden-Württemberg, Stuttgart, April 19, 2020 - After four weeks of standstill due to the corona pandemic in large parts of the production, the car manufacturer Daimler is starting up its plants again on Monday. Here is the Möhringen branch. *** DEU

When it comes to profits, the Corona crisis has slowed the company down considerably.

© imago images / Arnulf Hettrich, Arnulf Hettrich via www.imago-images.de, www.imago-images.de

The corona crisis led to a slump in profits for the automaker Daimler in the first quarter and makes it impossible to make a precise forecast for the year as a whole. From January to March, earnings before interest and taxes dropped 78 percent to 617 million euros, the Dax group announced in a mandatory announcement on Thursday night.

There were already deep signs of a brake on the Corona crisis when it came to sales: the passenger car subsidiary Mercedes-Benz sold 15 percent less worldwide in the first quarter, while sales in the truck business dropped 20 percent. Production at Daimler only started slowly again this week in Europe after a four-week break. The car dealerships opened. In China, production has already returned to normal.

07:20 – UN Secretary General: “The threat is the virus, not the people”

UN Secretary-General António Guterres has warned of respect for human rights in the fight against the corona virus. Combating corona should not be an excuse for repression. In some societies, hate speech would increase and minorities would become the target of aggression. “We have seen the virus itself not discriminate but its effects – by uncovering deep weaknesses in public services and structural inequalities that hinder access to them,” Guterres said in a video message Thursday. Human rights should therefore be at the center of the response to the pandemic. “Let us never forget – the threat is the virus, not the people.”

07:00 a.m. – Current figures from Germany and the world

country Infected dead
Worldwide 2,628,916 183,441
USA 842.376 46,784
Spain 208,389 21,717
Italy 187.327 25,085
France 157.135 21,340
Germany 150,648 5,315
Great Britain 134,638 18,100
Turkey 98,674 2,376

Source: Johns Hopkins University

6:30 a.m. – More short-time work allowance, less catering VAT

After a marathon session, the grand coalition agreed on new billion-dollar aid for employees, restaurants, businesses and schools at night. Short-time work benefits are to be increased in order to compensate for loss of income, especially for low-wage earners. The catering industry, which is particularly hard hit by the crisis, will receive tax relief. At the same time, the duration of the unemployment benefit is extended. An overview of the decisions.

11:00 p.m. – Current figures from Germany and the world

country Infected Deaths
USA 839.836 46,399
Spain 208,389 21,717
Italy 187.327 25.985
France 159,315 21,373
Germany 149,771 5,211
Great Britain 134,637 18,151
Worldwide 2,623,231 182,740

Source: Johns Hopkins University

10:25 p.m. – Denmark allows foreign family members to enter again

The Danish government eased entry requirements on Wednesday due to the corona pandemic. Foreign spouses and life partners as well as children and parents of Danes can now return to the country even if they do not have a residence permit. Denmark was one of the first countries in Europe to close almost the passenger border on March 14th due to the Corona crisis. Only foreigners who had an important reason were allowed to enter. “However, people with symptoms continue to be rejected at the border,” Foreign and Integration Minister Mattias Tesfaye said in parliament.

9:30 p.m. – Ramelow with everyday mask on the asparagus field

April 22, 2020, Thuringia, Kutzleben: Bodo Ramelow (Die Linke), Prime Minister of Thuringia, presents an asparagus spear in a field of the Spargelhof Kutzleben. The company in the Unstrut-Hainich district is one of the largest asparagus growers in Thuringia

Asparagus harvest at the Kutzleben asparagus farm

© dpa, Martin Schutt, msc htf

Black suit, blue tie – and a cloth over your mouth and nose: Thuringia’s Prime Minister Bodo Ramelow (left) set a good example on Wednesday with the asparagus pricking. The red and green cloth with which the head of government protected large parts of his face was, according to the imprint, a remnant from older times. It promoted the German Hiking Day three years ago – and “Luther 2017”.

8:55 pm – Virus detected for the first time in US pets

ARCHIVE - The two-month-old cat Delayla is sitting in the cat room of the animal shelter in Mainz on June 27th, 2008. While some enjoy their summer vacation in a relaxed manner, others have to toil: Animal shelters and pensions are always on during their long vacations

An infected person actually lived in just one household. (Icon image)

© dpa, Fredrik von Erichsen

In the USA, the novel corona virus has been detected in pets for the first time. Two domestic cats in the state of New York were tested positive for the SARS-CoV-2 virus, the US health agency CDC said on Wednesday. Both animals that lived in different locations in the state had had respiratory problems. In one case, the cat’s owner had previously tested positive for the virus. In the other case, no infection is known in the affected household.

The agency said there is currently no evidence that pets have played a role in the spread of the corona virus. There is therefore no reason for measures against pets. The health authority advised that pets outside of their own household should not be allowed to come into contact with other animals or people. Sick people should stay away from their pets and other animals.

8:30 p.m. – British virologist: little chance of vaccine in 2021

England’s chief medical officer Chris Whitty sees little chance of an effective remedy for the disease in the coming year. In the long term, there are two things you can get out of the current situation, he says: Either “through a highly effective vaccine and / or a very effective medication”. However, the probability that they will be available in the coming year is “incredibly low”. You have to see this realistically.

8:00 p.m. – Google is fishing dozens of hacker groups

Google claims to have identified more than a dozen government-sponsored hacker groups that are trying to use the pandemic for cyber attacks. The US company reports in its company blog that 18 million corresponding emails are intercepted.

6:55 pm – Drosten podcast nominated for the Grimme Online Award

The podcast “The Corona Virus Update” with the Berlin virologist Christian Drosten has been nominated for the Grimme Online Award. It has developed into an “instance” for listeners, the jury explained. He gave the virologist Drosten enough space to talk about current studies, symptoms or possible countermeasures – “and to correct himself due to new developments”. The podcast was still very often proposed for the award after the deadline.

“The need for information is very high, as the offers show, the selection of the nomination committee shows,” said Grimme Director Frauke Gerlach. It is particularly high when you live in times of crisis – like now in the Corona crisis.

6:45 pm – WHO: Most outbreaks in Europe are stable or decreasing

According to the World Health Organization (WHO), most outbreaks in Europe are now stable or are weakening. However, there are worrying increases in Central Europe, Africa and Central and South America, says WHO chief Tedros Adhanom Ghebreyesus.

6:16 p.m. – Hamburg court considers corona closure of large stores to be inadmissible

The Hamburg Administrative Court has declared the closure of stores with more than 800 square meters of retail space maintained by the Senate to curb the corona pandemic to be inadmissible. With a decision published on Wednesday, the court granted an urgent request from a sports shop in downtown Hamburg, a spokesman said. However, the Senate had already lodged an appeal against this with the Hamburg Higher Administrative Court and requested that the rules should remain pending a decision.

In the opinion of the administrative court, the loosening of the shop opening that has been in effect since Monday violates the right to freedom of occupation. Because the distinction made in the regulation between shops with a sales area of ​​less than 800 square meters, which are allowed to open, and larger ones, which are only allowed to open with a reduced area, “is, according to the administrative court, unsuitable to serve the purpose of infection protection pursued by the legal regulation “the court announced. Rather, this protection can be achieved in large stores “as well as or even better than in smaller facilities”.

You can read here what the previous easing measures in public space in the various federal states look like.

5:44 p.m. – Online music festival with big stars planned

In the corona crisis, the music label Warner Music, together with the World Health Organization (WHO), is organizing an online festival with excerpts from previous concerts by stars such as Coldplay, Ed Sheeran and Bruno Mars. The “Play On Fest” with performances by more than 65 musicians and bands should be on the Internet from April 24th to 26th, the US record company announced on Wednesday. All proceeds – such as donations or the purchase of merchandise – should go to the WHO in the fight against the corona pandemic.

5:36 p.m. – UKE fears second wave of corona in autumn

The University Medical Center Hamburg-Eppendorf (UKE) has warned of a second wave of corona infections at the end of summer. “I am afraid that we are actually facing a second wave, which could only start after the summer months, in August, and maybe not until the end of August (…),” said UKE CEO Prof. Burkhard Göke in Hamburg on Wednesday. “We are very concerned about the logistics of diagnostics.” If there are then many cold patients in the central emergency room, the UKE will be required to take a smear on everyone, possibly again at intervals. The UKE has already exhausted its diagnostic possibilities “to the limit of availability”, warned Göke.

He is also worried about the wave of influenza that will set in in autumn. The idea that the influenza A infection, which in itself can be very stressful and dangerous, would also pair with a Covid infection, gives him a headache, said the medical director of the UKE. With regard to intensive care, he said there is currently no capacity overload. “We are unsure about autumn.”

5:13 p.m. – Zoos in need: State of North Rhine-Westphalia helps with around 12 million euros

31.03.2020, North Rhine-Westphalia, Cologne: Lions lie in the outside enclosure in the deserted zoo and sunbathe. The zoos closed due to the corona crisis sound the alarm: they lack the revenue. (to dpa

Coronavirus – Cologne Zoo

© dpa, Rolf Vennenbernd, ve

NRW Finance Minister Lutz Lienenkämper (CDU) wants to help the zoos and zoos in the country with 11.825 million euros to deal with the consequences of the corona crisis. The zoos had “no significant financial reserves”. Lienenkämper wrote in a submission to the finance committee of the state parliament that this would endanger an adequate supply of animals and especially endangered animal species. The money should serve to compensate for the loss of revenue, secure liquidity and avert impending closures. The NRW zoos have been closed since March 18 and are therefore no longer paying entry fees. A zoo had published that there would be an emergency slaughter plan if feed was no longer available.

5:03 p.m. – Söder praises nationwide mask requirement

CSU chief Markus Söder has praised the announcements for a nationwide mask requirement due to the corona pandemic. “Good news: now there is a mask requirement in all 16 federal states. It is clear that the relief will be accompanied by protective measures,” wrote the Bavarian Prime Minister on Wednesday afternoon on Twitter, reports the dpa.

Before that, Bremen was the last federal state to announce the requirement to wear mouth-nose covers to protect against infection. The obligation applies in most countries – including Bavaria – from next week and mostly refers to buses and trains as well as shopping in shops. You can read about the regulations in your state here. You can read here how exactly the mask requirement should look in your state.

4:45 p.m. – Virologist Drosten: Germany may be wasting an important corona lead

Christian Drosten, Director at the Institute of Virology at Charite Berlin, taken as part of a press briefing from the Federal Ministry of Health on the spread of the corona virus. At the federal press conference in Berlin, March 9, 2020. Berlin D

Christian Drosten, Director at the Institute for Virology at Charite Berlin, taken as part of a press course

© imago images / photothek, Janine Schmitz / photothek.net via www.imago-images.de, www.imago-images.de

Virologist Christian Drosten sees the danger that Germany may lose previous successes in corona containment and the situation may slip away. He currently regrets “seeing so much that we are just about to lose this advantage here completely,” said the head of Virology at the Charité on Wednesday in the NDR podcast. In international comparison, Germany is one of the most successful countries in combating pandemics because the outbreak was recognized very early on.

It would not surprise him if one suddenly came into a situation over May and June that “we cannot control if we are not careful”, emphasized Drosten. There would then be many more starting points for the virus than at the beginning of the epidemic. Germany is currently in a very fragile area, said Drosten, referring to the number of reproductions recently estimated by the Robert Koch Institute at 0.9. This means that on average almost every infected person infects a different person.

4:24 p.m. – Estimate: number of British corona deaths twice as specified

In the UK, according to a Financial Times report, twice as many people may have died as a result of the coronavirus pandemic than previously thought. This is based on extrapolations by the newspaper based on figures from the British statistical office ONS. According to this, 41,000 people could have died in the wake of the pandemic. That is far more than the official figures suggest so far: According to the Ministry of Health, around 17,300 people have been shown to die of Monday from lung disease in hospitals in the country. This does not include deaths in nursing homes and private households.

The basis for the calculation of the “Financial Times” is the over-mortality rate in Great Britain, which the statistics office gave for the week up to April 10th with about 8000. That means that within a week, 8,000 more people died in the country than the average of previous years.

4:09 pm – Steinmeier: Can we work our way out of the economic valley again

Federal President Frank-Walter Steinmeier prepared citizens for difficult economic times in the face of the Corona crisis, but was optimistic about an upswing afterwards. In his new video message, he called for solidarity in the economy and warned against underestimating the risks of the crisis.

“Time will not pass us by without a trace. We will give up some of the prosperity we have developed together,” said Steinmeier. “But we are and we will remain a strong economy – with millions of people who want to continue to tackle or get going again. Just as we will defeat the virus together, we will work our way out of the economic valley with diligence and prudence.”

3:59 p.m. – German airports expect trough in second quarter

Impact of Corona Airport Munich In the picture Access Security Control Terminal 2 opened green. Munich Airport Munich Bavaria Germany *** Impact Corona Munich Airport In picture Access Security Control Terminal 2 open green Munich Airport

Impact of Corona Airport Munich In the picture Access Security Control Terminal 2 opened green. Munich Airport Mü

© imago images / Passion2Press, Markus Fischer via www.imago-images.de, www.imago-images.de

In view of the fact that air traffic is hardly taking place anymore, German airports expect the low point in passenger numbers in the current second quarter. In the Corona crisis, traffic had dropped to around 5 percent of the previous level by the end of March, as the airport association ADV reported again on Wednesday. Last week (April 13-19, 2019), the number of passengers fell to just 1.2 percent.

For March, the figures showed a 63 percent decrease compared to the same month in the previous year to 7.1 million passengers, which corresponds approximately to the volume of the 1990s. There was particularly little traffic on the domestic routes.

The airline Walter had already filed for bankruptcy on Wednesday.

News from April 22nd

You can read all developments from April 22nd here.

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