infectious diseases

New Antibiotic Combinations for Recurrent Bacterial Vaginosis

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Researchers at Monash University and Bayside Health’s Melbourne Sexual Health Centre are clinical-trialling antibiotic combinations to treat persistent bacterial vaginosis, following a landmark 2025 discovery in the New England Journal of Medicine that treating male partners cuts infection recurrence by over 60 percent. Antibiotic Trials Target Persistent Bacterial Vaginosis After Partner Treatment Discoveries Medical researchers … Read more

New National Guidelines Aim to Improve Sepsis Care

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New multisociety clinical guidelines released by the Infectious Diseases Society of America and seven other professional groups aim to standardize hospital workflows and improve survival rates for sepsis, a dangerous full-body infection that kills at least 350,000 Americans annually. According to Taison Bell, MD, MBA, interim chair of UVA Health’s Department of Medicine, the initiative … Read more

Asthma Antiviral Nasal Spray Secures Clinical Trial Funding

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A new Phase Ib clinical trial will evaluate whether a once-weekly dry powder nasal spray called INNA-051 can prime innate immune defenses and prevent viral complications in adult asthma patients, according to developer ENA Respiratory. The trial is backed by AUD $2.98 million in funding awarded through Biointelect Venturer, utilizing support from the Australian Government’s … Read more

COVID-19 Alters Sleep Breathing Patterns

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A history of COVID-19 does not disrupt the primary physiological mechanisms of obstructive sleep apnea, according to a study published in the Journal of Clinical Medicine. Researchers discovered that while upper-airway collapsibility and muscle compensation remain stable, individuals with a prior infection exhibit a significantly stronger breathing response after brief nighttime awakenings. Core Sleep Apnea … Read more

Mosquito Bite Vaccine: A New Breakthrough in Immunity

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Researchers at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, have developed a new vaccination approach that uses antimalarial drug compounds to transform mosquito bites from a source of deadly infection into natural immune boosters, according to a study published in Science. Targeting the Late Liver Stage to Build Durable Immunity The preclinical … Read more

Flesh-Eating Bacteria Summer Outbreak: Risks and Prevention

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Flesh-eating bacteria infections caused by Vibrio vulnificus are prompting urgent health warnings across Gulf and Eastern coastal states, where at least seven deaths have been confirmed this season according to officials cited by CBS News. The Centers for Disease Control and Prevention reports that about one in five people who contract the severe necrotizing fasciitis … Read more

T Cell Exhaustion in Organ Transplantation: Mechanisms and Therapies

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According to a comprehensive review published in Genes & Diseases by Yining Wang and colleagues, T cell exhaustion plays a complex and dual role in organ transplantation, acting both as a mechanism to promote graft tolerance and as a source of vulnerability to infections and malignancies. The dysfunctional immune state develops during prolonged antigen exposure, … Read more

Dexamethasone Calms Lung Inflammation Without Harming Immunity

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Researchers at Trinity College Dublin and St. James’s Hospital have demonstrated that dexamethasone, a commonly prescribed anti-inflammatory steroid, reduces harmful inflammation triggered by Mycobacterium avium without weakening the ability of human immune cells to control the infection, according to a study published in the Journal of Infectious Diseases. Understanding Nontuberculous Mycobacterial Disease and Treatment Challenges … Read more

Candida auris Hair Follicle Persistence and Immune Evasion

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Candida auris causes roughly 3,000 deaths each year among patients in U.S. hospitals and long-term care facilities, according to federal health data, prompting researchers to investigate how this multidrug-resistant pathogenic yeast persists on human skin. While the fungus has been known to colonize the skin since its discovery in 2009, scientists have lacked a clear … Read more

New Breakthrough in the Fight Against Antibiotic Resistance

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Antimicrobial Peptide Research Reveals Unexpected Bacterial Rigidity Research led by Cornell College faculty and students indicates that the antimicrobial peptide Magainin 2 induces unexpected biomechanical changes in Escherichia coli when administered at high concentrations. Contrary to previous assumptions that peptides soften bacterial cell walls, the study found that high doses cause E. coli to become … Read more

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