People living with well-controlled HIV face an elevated risk of developing type 2 diabetes due to increased scarring in their fat tissues, according to a University of California – San Francisco study published June 30 in JCI Insight. Fat Fibrosis and Insulin Resistance in HIV Researchers at UCSF investigated why patients with suppressed HIV maintain … Read more
FOXA2 serves as a master transcription factor that coordinates pancreatic development, maintains islet cell identity, and regulates systemic glucose homeostasis, according to a review published in the journal Genes & Diseases (DOI: 10.1016/j.gendis.2025.101972). By orchestrating gene networks from early organogenesis into adulthood, FOXA2 ensures the functional integrity of insulin-producing β-cells and glucagon-secreting α-cells, providing a … Read more
Daily consumption of raw tomatoes and tomato sauce significantly reduces controlled attenuation parameter (CAP)-defined hepatic steatosis in adults with metabolic dysfunction-associated steatotic liver disease (MASLD), according to an exploratory randomized controlled trial published in the journal Nutrients. Researchers found that a six-week tomato-rich diet outperformed a tomato-free control group, dropping median CAP values by 35 … Read more
A study published in the journal Nutrients has linked high consumption of ultra-processed foods (UPFs) to early, measurable changes in insulin secretion and sensitivity among nondiabetic children. Researchers analyzed data from the San Antonio Family Assessment of Metabolic Risk Indicators in Youth (SAFARI) study, finding that higher UPF intake correlates with markers of insulin resistance … Read more
A recent cross-sectional study published in the journal Nutrients found no statistically significant link between an individual’s chronotype—their natural preference for morning or evening activity—and the presence of liver fat or fibrosis in adults with overweight or obesity. Researchers at the National Institute of Gastroenterology in Italy assessed 119 medication-naïve participants using the Morningness–Eveningness Questionnaire … Read more
Lactoferrin-fortified yogurt maintains ferritin levels in pregnant women with gestational diabetes mellitus (GDM) without causing iron overload, according to a randomized trial published in npj Science of Food. The study found that 100 mg of bovine lactoferrin per serving helped stabilize iron stores in women with reduced ferritin, offering a well-tolerated alternative to relying solely … Read more
The Future of Obesity Treatment: Why Precision Medicine is the New Frontier For decades, the medical community viewed weight loss primarily through the lens of caloric balance. However, groundbreaking long-term research—most notably the Swedish Obese Subjects (SOS) study—is fundamentally shifting that narrative. We are entering an era where weight management is no longer just about … Read more
Beyond Reproductive Years: How Polycystic Ovary Syndrome (PMOS) Is Reshaping Women’s Health in Midlife—and What’s Next Polyendocrine Ovarian Syndrome (PMOS)—formerly known as Polycystic Ovary Syndrome (PCOS)—is no longer just a condition tied to reproductive health. As women transition through perimenopause and menopause, the long-term metabolic, hormonal, and psychological impacts of PMOS become more pronounced, yet … Read more
Beyond “Plant-Based”: Why Quality is the New Gold Standard for Pregnancy Nutrition For years, the nutritional conversation around pregnancy has been binary: eat meat or go plant-based. However, emerging data is shifting the narrative. A recent analysis of NHANES (National Health and Nutrition Examination Survey) data suggests that for expectant mothers, what plants you eat … Read more
Beyond the Blame Game: The Future of How We Talk About Diabetes For decades, the narrative surrounding diabetes has been split down a rigid line. On one side, Type 1 diabetes (T1D) is framed as a biological lottery—an unfortunate medical event. On the other, Type 2 diabetes (T2D) is frequently painted as a personal failure, … Read more