Higher levels of trimethylamine N-oxide (TMAO) are independently associated with a greater prevalence of atrial fibrillation (AF), according to a study published in The Journal of Clinical Investigation. Researchers found that TMAO, a metabolite produced by gut microbes from nutrients like choline, may trigger AF by inhibiting muscarinic receptor 2 signaling and disrupting autonomic regulation … Read more
Inherited genetics directly shape how our DNA interacts with acquired mutations to drive tumor evolution, according to research published in Nature. Scientists at the University of Cambridge and the University of Edinburgh found that an individual’s genetic background dictates both cancer risk and the specific evolutionary paths tumors take, offering new direction for precision medicine … Read more
Primary biliary cholangitis is a rare autoimmune disease affecting small bile ducts within the liver, causing bile to build up and trigger progressive liver damage that can eventually lead to cirrhosis, according to recent medical studies. Because the immune system attacks these vital ducts, roughly 40% of patients fail to respond adequately or cannot tolerate … Read more
A recent cross-sectional study published in the journal Nutrients found no statistically significant link between an individual’s chronotype—their natural preference for morning or evening activity—and the presence of liver fat or fibrosis in adults with overweight or obesity. Researchers at the National Institute of Gastroenterology in Italy assessed 119 medication-naïve participants using the Morningness–Eveningness Questionnaire … Read more
Stanford Medicine researchers have identified a primary driver of biological aging: the failure of tissue-resident macrophages to clear senescent, or “zombie,” neutrophils from the body. According to a study published July 16 in Science, blocking a specific pro-inflammatory receptor, EP2, on these immune cells rejuvenated organ function and reduced age-related frailty in mice. This discovery … Read more
Metabolic dysfunction-associated steatotic liver disease (MASLD) may affect up to 47% of adults in Mexico, according to a review published in Archives of Medical Research. Lead author Jeffrey Lazarus, a professor at the CUNY Graduate School of Public Health and Health Policy, argues that Mexico must integrate liver health into existing obesity and diabetes programs … Read more
Researchers at Sungkyunkwan University (SKKU), in collaboration with the Catholic University of Korea and Eunpyeong St. Mary’s Hospital, have developed an ultrasensitive electrochemical biosensor capable of detecting early-stage liver fibrosis through a small blood sample. The device, known as FIB-EIS, identifies the protein PICP to signal liver hardening, potentially replacing invasive tissue biopsies with a … Read more
Exposure to space radiation and microgravity triggers rapid genetic changes in the liver that mirror the human aging process, according to research published in the journal GeroScience. How does space travel accelerate the aging process? Space environments force the human body to endure conditions that trigger premature biological decline. Michal Masternak, a professor of medicine … Read more
A blood test detecting circulating tumour DNA (ctDNA) after surgery can identify colorectal cancer patients most likely to benefit from adjuvant chemotherapy, according to research presented at the 2026 ESMO Gastrointestinal Cancers Congress. The Phase II GALAXY study, led by researchers from Hyogo Medical University and collaborators including the University of Oxford, found that patients … Read more
High coffee consumption is linked to a significantly lower risk of cirrhosis, liver cancer, and liver-related deaths, according to a study published in Clinical Gastroenterology and Hepatology. Researchers tracking more than 350,000 participants from the UK Biobank found that individuals drinking five or more cups of coffee daily had a 32% lower risk of cirrhosis … Read more