Human-AI Co-Design for Clinical Prediction Models
HACHI is an iterative human-in-the-loop framework that utilizes AI agents to accelerate the development of fully interpretable clinical prediction models (CPMs) from unstructured clinical notes. By alternating between AI-driven statistical exploration and expert human feedback, the system optimizes for transparency and steerability, demonstrably outperforming traditional modeling approaches in tasks like acute kidney injury and traumatic … Read more