Radiation exposure to the thymus during non-small cell lung cancer treatment is associated with worse outcomes in patients being treated for non-small cell lung cancer (NSCLC), according to a study published in the journal Annals of Oncology. Thymus Health and Radiation Risks in NSCLC Patients Until recently, the thymus was thought to be of little … Read more
Stereotactic body radiation therapy improves bowel health-related quality of life for patients with localized intermediate-risk prostate cancer compared to moderately hypofractionated intensity-modulated radiation therapy, according to findings from the NRG-GU005 clinical trial published in the Journal of the American Medical Association. NRG-GU005 Trial Design and Patient Demographics The Phase III NRG-GU005 trial evaluated 698 evaluable … Read more
Genomic newborn screening using heel-stick blood spots can identify infants at high risk for early-onset cancers before symptoms appear, according to a Nature Communications study led by researchers from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Mass General Brigham, and collaborators. Analyzing archived samples from 1,948 children in Michigan who developed solid or central nervous … Read more
Systemic cancer therapy timing significantly influences both treatment effectiveness and safety, according to a recent systematic review published in Critical Reviews in Oncology/Hematology (Ghidini A et al., August 2026). Aligning treatments with individual circadian rhythms, seasonal variations, and vitamin D levels could reshape how oncologists administer chemotherapy and immunotherapy. Circadian Rhythms and Molecular Biology in … Read more
According to research published in the Chinese Medical Journal, a mitochondrial matrix protein known as RTN4IP1 drives the progression and metastasis of triple-negative breast cancer by disrupting cellular energy metabolism. Triple-negative breast cancer accounts for roughly 15% of all breast cases and lacks estrogen, progesterone, and HER2 receptors, leaving patients with high risks of recurrence … Read more
According to a study published on August 7, 2026, in Volume 17 of Oncotarget, treatment with the multi-kinase inhibitor K252a transiently delayed the growth of SK-ES-1 Ewing sarcoma tumor xenografts in immunodeficient mice. Led by researchers at the Federal University of Rio Grande do Sul and INCT BioOncoPed in Brazil, the team found that the … Read more
Researchers at Nankai University have developed a framework for integrated nanomaterials designed to overcome the physiological and immune-based barriers that frequently limit the effectiveness of cancer immunotherapy. Published April 24, 2026, in the Chinese Journal of Polymer Science, the study outlines how coordinated nanomaterial design can improve drug delivery, antigen presentation, and tumor microenvironment reprogramming … Read more
Lactylation-driven metabolic reprogramming acts as a central driver of therapeutic resistance in cancer, according to recent findings published in the journal Genes & Diseases by researchers Wanghao Zhang, Guanglong Huang, Woheng Tang, Jiaxian Li, Jingxian Chen, Yaojiang Feng, Kaichen Li, Can Pan, Shunshen Li, Huayang Zhang, Rongxu Ye, Hao Long, and Guo-zhong Yi. This cellular … Read more
Astrin Biosciences is expanding physician outreach and preparing a direct-to-consumer launch for Certitude, a proteomic-based breast cancer diagnostic test that leverages mass spectrometry and machine learning. According to the company, the test identifies high-risk patients and detects early-stage malignancies from a small plasma sample. How Proteomics and AI Outperform Traditional DNA Liquid Biopsies in Early … Read more
Insilico Medicine published a collaborative study in the journal npj Precision Oncology, detailing how artificial intelligence and multi-omic analysis identified therapeutic targets in inverted papilloma-associated sinonasal squamous cell carcinoma (IP-SNSCC), a rare head and neck cancer. Conducted with researchers from the University of Chicago and Johns Hopkins University, the peer-reviewed paper offers the first comprehensive … Read more