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Prolonged physical exercises and playing sports is an effective way to avoid and even to some extent to overcome some chronic diseases associated with metabolism, e.g., diabetes or metabolic syndrome. To such conclusion scientists from the Karolinska Institute inand the University of San Diego in the United States as a result of their research, reported in the journal Cell Reports.
The experiment involved eighteen people engaged in Jogging, Cycling and other endurance exercises at least 15 years and seven men, who regularly perform strength exercises.
The researchers found that frequent physical activity changes the activity (expression) 1 711 metabolic genes in women and 1,097 genes in men. That is, the endurance training significantly improves processes associated with the tricarboxylic acid cycle (Krebs cycle), which plays a key role in metabolism.
Those who performed strength training had only 26 genes, which changed their activity. However, this does not mean, however, training does not have any effect. They can directly affect the activity of proteins and not on gene expression.
Experts also compared the obtained results with the data about the change of gene activity in people with metabolic syndrome and type II diabetes.
By the way, the subjects periodically performed exercises for about 6-12 months, after which the situation with the expression of the genes was similar to that observed in the new study, people performing endurance exercise for many years.