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Updated Dec. 27, 2025, 8:14 a.m. MT
Who will win the first Saturday game in NFL Week 17?
The Houston Texans and Los Angeles Chargers play on Saturday, Dec. 27, at the Chargers’ SoFi Stadium in a game on the NFL Week 17 schedule.
What do NFL Week 17 odds say about the game? Who are NFL Week 17 predictions and NFL Week 17 picks taking in the game?
Which team has the best chance to win the game according to NFL Week 17 win probabilities?
Check out The Arizona Republic’s score prediction for the game, as well as Texans vs Chargers picks, odds and win chances for the Dec. 27 NFL Week 17 game, which can be seen at 2:30 p.m. MST on NFL Network (stream on FUBO).
NFL Week 17 picks: Cowboys at Commanders | Lions at Vikings | Broncos at Chiefs | Texans at Chargers | Ravens at Packers | Seahawks at Panthers | Cardinals at Bengals | Steelers at Browns | Jaguars at Colts | Buccaneers at Dolphins | Patriots at Jets | Saints at Titans | Giants at Raiders | Eagles at Bills | Bears at 49ers | Rams at Falcons | The Republic’s score predictions
Watch Texans at Chargers game on FUBO (free trial)
NFL Saturday prediction for Chargers vs Texans game
The Arizona Republic is predicting a 21-17 win for the Texans over the Chargers in the NFL Week 17 football game.
Jeremy Cluff writes: “Justin Herbert and the Chargers are 5-2 at home and have won four in a row, but the Texans’ defense can wreak some havoc, especially against the Los Angeles offensive line. Houston will win its eighth straight game.”
NFL Saturday picks for Texans vs Chargers game
Will the Chargers or Texans win the game in NFL Week 17?
Bookies.com says to be the Texans with the points against the Chargers today.
Sports Betting Dime’s formula predicts a 4-point win for the Texans over the Chargers.
Dimers.com’s final score predictions for the NFL Week 17 game? Texans 21, Chargers 18.
Sportsnaut is predicting a 17-13 win for the Texans over the Chargers on Dec. 27.
NFL Saturday win probabilities for Chargers vs Texans game
The Chargers have a 52.4% chance to beat the Texans, according to ESPN.
The site gives the Texans a 47.2% shot at winning the NFL Week 17 game, with the remaining percentage accounting for a tie.
NFL Saturday odds for Texans vs Chargers game
The Chargers are a 2-point favorite over the Texans in NFL Week 17 odds for the game, courtesy of BetMGM Sportsbook.
Los Angeles is -130 on the moneyline, while Houston is +110.
The over/under (point total) is set at 39.5 points.
NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team
Reach Jeremy Cluff at [email protected]. Follow him on X, formerly Twitter @Jeremy_Cluff.
Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.
Gambling involves risk. Please only gamble with funds that you can comfortably afford to lose. While we do our utmost to offer good advice and information we cannot be held responsible for any loss that may be incurred as a result of gambling. We do our best to make sure all the information that we provide on this site is correct. However, from time to time mistakes will be made and we will not be held liable. Please check any stats or information if you are unsure how accurate they are. No guarantees are made with regards to results or financial gain. All forms of betting carry financial risk and it is up to the individual to make bets with or without the assistance of information provided on this site and we cannot be held responsible for any loss that may be incurred as a result of following the betting tips provided on this site. Past performances do not guarantee success in the future and betting odds fluctuate from one minute to the next. The material contained on this site is intended to inform, entertain and educate the reader and in no way represents an inducement to gamble legally or illegally or any sort of professional advice.
Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside. It is your sole responsibility to act in accordance with your local laws.
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Updated Dec. 27, 2025, 8:14 a.m. MT
Who will win the first Saturday game in NFL Week 17?
The Houston Texans and Los Angeles Chargers play on Saturday, Dec. 27, at the Chargers’ SoFi Stadium in a game on the NFL Week 17 schedule.
What do NFL Week 17 odds say about the game? Who are NFL Week 17 predictions and NFL Week 17 picks taking in the game?
Which team has the best chance to win the game according to NFL Week 17 win probabilities?
Check out The Arizona Republic’s score prediction for the game, as well as Texans vs Chargers picks, odds and win chances for the Dec. 27 NFL Week 17 game, which can be seen at 2:30 p.m. MST on NFL Network (stream on FUBO).
NFL Week 17 picks: Cowboys at Commanders | Lions at Vikings | Broncos at Chiefs | Texans at Chargers | Ravens at Packers | Seahawks at Panthers | Cardinals at Bengals | Steelers at Browns | Jaguars at Colts | Buccaneers at Dolphins | Patriots at Jets | Saints at Titans | Giants at Raiders | Eagles at Bills | Bears at 49ers | Rams at Falcons | The Republic’s score predictions
Watch Texans at Chargers game on FUBO (free trial)
NFL Saturday prediction for Chargers vs Texans game
The Arizona Republic is predicting a 21-17 win for the Texans over the Chargers in the NFL Week 17 football game.
Jeremy Cluff writes: “Justin Herbert and the Chargers are 5-2 at home and have won four in a row, but the Texans’ defense can wreak some havoc, especially against the Los Angeles offensive line. Houston will win its eighth straight game.”
NFL Saturday picks for Texans vs Chargers game
Will the Chargers or Texans win the game in NFL Week 17?
Bookies.com says to be the Texans with the points against the Chargers today.
Sports Betting Dime’s formula predicts a 4-point win for the Texans over the Chargers.
Dimers.com’s final score predictions for the NFL Week 17 game? Texans 21, Chargers 18.
Sportsnaut is predicting a 17-13 win for the Texans over the Chargers on Dec. 27.
NFL Saturday win probabilities for Chargers vs Texans game
The Chargers have a 52.4% chance to beat the Texans, according to ESPN.
The site gives the Texans a 47.2% shot at winning the NFL Week 17 game, with the remaining percentage accounting for a tie.
NFL Saturday odds for Texans vs Chargers game
The Chargers are a 2-point favorite over the Texans in NFL Week 17 odds for the game, courtesy of BetMGM Sportsbook.
Los Angeles is -130 on the moneyline, while Houston is +110.
The over/under (point total) is set at 39.5 points.
NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team
Reach Jeremy Cluff at [email protected]. Follow him on X, formerly Twitter @Jeremy_Cluff.
Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.
Gambling involves risk. Please only gamble with funds that you can comfortably afford to lose. While we do our utmost to offer good advice and information we cannot be held responsible for any loss that may be incurred as a result of gambling. We do our best to make sure all the information that we provide on this site is correct. However, from time to time mistakes will be made and we will not be held liable. Please check any stats or information if you are unsure how accurate they are. No guarantees are made with regards to results or financial gain. All forms of betting carry financial risk and it is up to the individual to make bets with or without the assistance of information provided on this site and we cannot be held responsible for any loss that may be incurred as a result of following the betting tips provided on this site. Past performances do not guarantee success in the future and betting odds fluctuate from one minute to the next. The material contained on this site is intended to inform, entertain and educate the reader and in no way represents an inducement to gamble legally or illegally or any sort of professional advice.
Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside. It is your sole responsibility to act in accordance with your local laws.
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