Time for a different approach in the exam room: deprescribing

by Chief Editor

The Rising Tide of Polypharmacy: Why Less Medication May Be More

More than 20% of U.S. Adults are navigating the complexities of polypharmacy – taking five or more prescription medications monthly. This growing trend isn’t simply a matter of increased diagnoses; it’s prompting a critical reevaluation of medication management, with the American Medical Association (AMA) leading the charge towards a practice called “deprescribing.”

Understanding Polypharmacy and Its Impact

Polypharmacy disproportionately affects older adults and individuals managing multiple health conditions. Even as each medication may address a specific ailment, the cumulative effect can increase the risk of falls, cognitive decline, and adverse events, leading to tens of thousands of emergency room visits and hospitalizations annually. Among adults aged 60-79, over one-third are currently taking five or more prescription drugs.

Did you know? The proportion of older adults taking five or more medications tripled from 13.8% in 1994 to 42.4% in 2014, and could impact nearly half of the older population by 2030.

Deprescribing: A Latest Approach to Patient Care

Deprescribing is defined as the planned, supervised process of reducing or stopping medications that may no longer be beneficial—or may be causing harm. It’s not about denying necessary care, but rather ensuring every prescribed medication remains essential, evidence-based, and aligned with a patient’s current health goals. Reasons for deprescribing include a patient’s condition improving, the availability of newer, more effective treatments, or the introduction of over-the-counter drugs or supplements.

The AMA’s Call to Action

The AMA is urging physicians and patients to engage in open conversations about medication benefits and risks. This includes bringing all medications – including over-the-counter drugs and supplements – to appointments for comprehensive review. The AMA also advocates for improvements in medication reconciliation within electronic health records to minimize inaccuracies.

Beyond Medication: The Role of Lifestyle

Experts emphasize that effective healthcare extends beyond simply managing symptoms with medication. A holistic approach incorporating lifestyle factors – nutrition, physical activity, sleep, stress management, and social connection – is crucial for long-term health and well-being. The goal is to rethink the entire approach to health, considering both medication and lifestyle interventions.

Pro Tip: Keep an updated list of all medications, including dosages, and share it with your doctor at every appointment. Don’t forget to mention any vitamins, supplements, or herbal remedies you’re taking.

Future Trends in Medication Management

Several trends are likely to shape the future of medication management:

  • Increased Focus on Geriatric Pharmacology: As the population ages, there will be a greater need for specialized knowledge in geriatric pharmacology to address the unique challenges of polypharmacy in older adults.
  • Integration of Pharmacogenomics: Pharmacogenomic testing, which analyzes how a person’s genes affect their response to drugs, could grow more commonplace, allowing for more personalized medication prescriptions.
  • AI-Powered Medication Review Tools: Artificial intelligence (AI) may play a role in identifying potential drug interactions and suggesting deprescribing opportunities.
  • Enhanced Patient Engagement: Patients will likely become more active participants in their medication management, utilizing mobile apps and online portals to track their medications and communicate with their healthcare providers.
  • Value-Based Care Models: The shift towards value-based care, which emphasizes outcomes over volume, may incentivize deprescribing efforts to reduce healthcare costs and improve patient quality of life.

AMA Policy and Resources

The AMA has established policies to support safer medication practices, including:

  • Educating patients about the effects of all medications and supplements.
  • Encouraging physicians to discuss minimizing medication use with patients.
  • Working with stakeholders and EHR vendors to improve medication reconciliation accuracy.

The AMA offers resources like the STEPS Forward® toolkits and CME modules through the AMA Ed Hub™ to help physicians evaluate medications more holistically.

Frequently Asked Questions (FAQ)

Q: What is the difference between polypharmacy and appropriate polypharmacy?
A: Polypharmacy simply refers to taking multiple medications. Appropriate polypharmacy occurs when multiple medications are necessary to treat multiple conditions effectively.

Q: Is deprescribing the same as stopping medication abruptly?
A: No. Deprescribing is a planned and supervised process conducted in consultation with a healthcare professional.

Q: How can I start a conversation with my doctor about deprescribing?
A: Bring a complete list of your medications and supplements to your appointment and ask if any medications could be safely reduced or stopped.

Q: What role do pharmacists play in deprescribing?
A: Pharmacists can provide valuable expertise in medication review and identify potential deprescribing opportunities.

Learn more: Explore the AMA website for additional resources on deprescribing and medication safety.

What are your thoughts on the growing trend of polypharmacy? Share your experiences and questions in the comments below.

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