Friday, January 21, 2022 | 08:21 WIB
Eye surgery. [shutterstock]
KlikBabel.com – Data from the World Health Organization (WHO) states that glaucoma is the third leading cause of blindness globally, after refractive errors and cataracts.
Globally, glaucoma is the leading cause of irreversible blindness. The number of sufferers is predicted to reach 76 million worldwide.
In Indonesia itself, the data that was officially released showed that the prevalence of glaucoma was 0.46 percent or every 4 to 5 people per 1,000 population. More specifically, a study showed that in DKI Jakarta, the prevalence of primary angle-closure glaucoma (GPSTp) was 1.89%, while open-angle glaucoma (GPSTa) was 0.48, and secondary glaucoma was 0.16.
Barely asymptomatic in its early stages, glaucoma has the potential to have a more fatal impact: permanent blindness. Increased intraocular pressure (IOP) is a major risk factor for glaucoma.
However, in addition, anatomical factors also have an effect, especially in patients with chronic primary angle-closure glaucoma. Early detection, one of which is eye anatomy examination, is becoming increasingly crucial.
“Individuals with primary angle-closure glaucoma tend to have a shallower or narrower anterior chamber. Other anatomical factors, such as short eyeball axis, thickened lens, and shortened distance between the lens and the posterior iris surface, contribute to this category of glaucoma,” said Dr. Iwan Soebijantoro, SpM(K), JEC Glaucoma Subspecialist in his recent statement.
As a practitioner, Iwan was moved to uncover the possibility of other factors in order to find an early diagnosis and new treatment for people with GPSTp. Therefore, a study was initiated to determine the correlation between corneal endothelial damage in primary angle-closure glaucoma, especially in the chronic category.
The research initiated by Dr. Iwan Soebijantoro, SpM(K) stated in his dissertation “Relationship of Superficial Anterior Chamber with Corneal Endothelial Morphological Changes in Chronic Primary Angle Closure Glaucoma”.
Iwan found clinically applicable results, namely, very shallow anterior chamber angles (15 degrees or less) had more severe consequences, patients with corneal endothelial cells less than 2000 cells/mm2 had more severe RNFL thinning, and thickness central cornea, as long as within the normal range of 500-550 m, correlates with nerve cell depletion
“This research is the first part of a road map that aims to study the characteristics of the cornea, especially corneal endothelial cells in chronic GPSTp. The existence of a relationship between corneal endothelial cell density and retinal nerve fiber layer (RNFL) thickness is expected to be an alternative or supporting examination in assessing the severity of chronic GPSTp experienced by patients, “explained Dr. Iwan Soebijantoro, SpM(K).
“The results of this study further confirm that a systematic and careful clinical examination of the anatomy of the eye is still the basis for the management of glaucoma. That is, without waiting for complaints, eye examinations should be carried out as early as possible and periodically. Not only for people with primary angle-closure glaucoma, but for all people,” continued Dr. Iwan Soebijantoro, SpM(K).
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