The sudden death of Dr. Chandrashekhar Pakhmode, a renowned neurosurgeon from Nagpur, at the age of 53 on December 31, has prompted questions about the limitations of standard heart attack risk assessments. Despite being fitness-conscious and having a recent, clear ECG, Dr. Pakhmode collapsed and could not be revived despite immediate medical attention.
The Role of Stress and Blockages
Dr. Ranjan Shetty, lead cardiologist and medical director at Sparsh Hospital in Bengaluru, explained that stress, long work hours, and burnout are significant risk factors for heart attacks among doctors. He stated that, even with normal traditional markers, these factors can be the “greatest risk trigger.” A blockage in the left main artery, or the Left Anterior Descending (LAD) artery, is particularly dangerous due to the substantial amount of heart muscle affected.
A complete blockage of the left main artery can cut off approximately 50% of the blood supply to a critical part of the heart, leading to damage and potentially fatal arrhythmias.
Stress as a Trigger
According to Dr. Shetty, chronic stress and burnout cause inflammation that weakens blood vessels, making them susceptible to plaque buildup. Stress hormones like adrenaline and cortisol also contribute to increased heart rate, blood pressure, and cholesterol levels, ultimately damaging the heart over time. Even short-term stress can dislodge existing plaque, triggering a heart attack. A study published in The Lancet showed individuals reporting high stress levels were 2.5 times more likely to experience a heart attack.
The body experiences a surge of stress hormones between 3 am and 6 am, increasing heart rate and blood pressure. This, combined with additional stress, can constrict arteries and dislodge plaques, increasing the risk of a heart attack.
Limitations of Standard Testing
An ECG may not detect early stages of a heart attack or pick up electrical signals immediately. Individuals with diabetes may also exhibit few symptoms and minimal changes on an ECG. A routine ECG can miss unstable angina, a condition involving restricted blood flow without immediate damage, necessitating troponin protein blood tests to detect heart muscle damage.
Frequently Asked Questions
Can stress alone cause a heart attack in a healthy person?
Yes, stress and burnout can lead to chronic inflammation and weaken blood vessels, making them prone to plaque buildup and increasing the risk of a heart attack, even in individuals who are otherwise fit.
What makes a blockage in the left main artery so dangerous?
A 100% blockage of the left main artery cuts off about 50% of the oxygenated blood supply to a critical section of the heart muscle, causing significant damage and potentially leading to arrhythmia and sudden cardiac arrest.
Can a recent ECG miss a developing heart problem?
Yes, an ECG might appear normal in the early stages of a heart attack and may not always detect subtle changes or conditions like unstable angina.
Given the potential for undetected cardiovascular strain, particularly among high-stress professions, what further preventative measures might be considered to safeguard the health of individuals like Dr. Pakhmode?
