NICE is developing new draft guidelines to standardize the diagnosis and management of PMOS, focusing on earlier detection and improved consistency of care. The recommendations include annual reviews and highlight that healthcare professionals should consider PMOS in women of Black, Asian, and mixed ethnicity, as well as those who have undergone menopause.
How will the new NICE guidelines improve PMOS diagnosis?
These recommendations cover when healthcare providers should suspect PMOS, how to conduct assessments, and the specific protocols for reaching a diagnosis.
Marie Anne Ledingham, a consultant clinical advisor for women’s and reproductive health at NICE, noted that the inclusion of a “simple” annual review is a significant development. According to Ledingham, the new guidelines are intended to improve the consistency of care, increase general awareness, and support both earlier diagnosis and more effective management of the condition.
Which demographics are at higher risk for PMOS?
The draft guidelines highlight specific populations that may face higher risks or require more attentive assessment. NICE states that PMOS is thought to be more common in women of Black, Asian, and mixed ethnicity.
Because of this prevalence, NICE advises that healthcare professionals “should consider this when assessing symptoms” to ensure equitable care. Furthermore, the guidelines clarify that PMOS should not be discounted in women who have already transitioned through menopause, addressing a potential gap in current diagnostic practices.
What are the mental health implications of PMOS?
Beyond physical symptoms, the draft guidelines address the psychological burden associated with the condition. Living with PMOS can have a significant impact on an individual’s mental health and overall quality of life.
According to the NICE draft, depression and anxiety are common among those living with PMOS. This connection underscores the need for holistic care that addresses both endocrine health and psychological well-being.
What should be considered when planning a pregnancy with PMOS?
For individuals planning a pregnancy, the NICE guidelines recommend a multi-faceted approach to health management. The draft suggests that clinical advice should move beyond hormonal treatment to include several lifestyle-based factors.
The recommended areas of focus include:
- Weight management
- Diet and nutritional intake
- Regular exercise
- Sleep hygiene
- Mental health stability
When will the final PMOS guidelines be released?
The development of these guidelines is currently in the consultation phase. NICE has opened the draft for feedback from healthcare professionals, patients, and the general public from 1 July to 11 August 2026.

Following the consultation period, NICE expects to publish the final, official guidelines on PMOS in December 2026.
Frequently Asked Questions
Can PMOS affect women after menopause?
Yes. According to the NICE draft guidelines, the condition should not be discounted in women who have gone through menopause.
Which ethnic groups are more likely to have PMOS?
NICE indicates that PMOS is thought to be more common in women of Black, Asian, and mixed ethnicity.
What is the purpose of the annual review mentioned by NICE?
The annual review is intended to improve consistency of care and support earlier diagnosis and management of the condition.
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