Nick Sirianni to Provide Update Wednesday on Saquon Barkley Injury

Philadelphia Eagles running back Saquon Barkley suffered a hamstring injury during a 24-20 loss to the Los Angeles Rams on October 4, 2026. Coach Nick Sirianni stated the team will provide updates on Barkley’s status on Wednesday as the franchise faces mounting offensive injuries ahead of a game against the Jacksonville Jaguars.

The Philadelphia Eagles lost more than just a football game on a rainy Sunday at Lincoln Financial Field. Fox broadcaster Tom Brady noted from the booth that wet conditions at Lincoln Financial Field may have contributed to the setback as the running back planted and drove early in the contest. Saquon Barkley exited the 24-20 defeat against the Los Angeles Rams in the first quarter after grabbing his right hamstring following a six-yard run, leaving the stadium unassisted before being officially ruled out before halftime.

Testing on Monday brought some relief. Head coach Nick Sirianni told reporters that the team will evaluate treatment responses and have more answers on Wednesday. NFL Network’s Ian Rapoport reported that Barkley’s injury does not seem to be overly serious, though his availability for an upcoming game against the Jacksonville Jaguars in London is uncertain.

Backfield Depletion Compounds Eagles Roster Concerns Against the Rams

Barkley’s exit immediately strained an already heavily depleted Philadelphia offense. The Eagles hold an 18-29 career record in games played without Johnson. The team played without tight end Dallas Goedert, wide receiver DeVonta Smith, linebacker Zack Baun, and right tackle Lane Johnson, who was a late scratch for personal reasons.

“We didn’t get it, so that’s on me. A lot of things that we’ve got to look at and see what went down on that particular play, obviously same deal.”

Nick Sirianni, Head Coach

Sirianni Blames Himself for Failed Fourth-Down Gamble

With the offense missing key weapons, Sirianni faced questions regarding a critical fourth-quarter decision. Trailing late in the game, the coach opted against kicking a short field goal that would have extended Philadelphia’s lead to 23-10, choosing instead to go for it on fourth down. Jalen Hurts’ pass attempt to Darius Cooper fell short, giving the Rams new life before they mounted a game-winning drive.

Nick Sirianni to Provide Update Wednesday on Saquon Barkley Injury
Photo: CBS News

Hurts finished the afternoon 12 of 27 for 93 yards while absorbing two sacks on the final possession. Sirianni similarly shouldered the blame for the failed fourth-down gamble while acknowledging that the team is still trying to figure out its identity four games into the season.