Cell

UH College of Pharmacy Secures Funding for Three Major Health Studies

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University of Houston College of Pharmacy researchers secured more than $1 million in new funding to tackle three distinct healthcare challenges, including sepsis, Alzheimer’s disease, and sickle cell-related depression, according to institutional announcements. The grants back projects aimed at developing new drug delivery systems, artificial intelligence tools, and specialized diagnostic screeners to improve patient outcomes. … Read more

Dexamethasone Calms Lung Inflammation Without Harming Immunity

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Researchers at Trinity College Dublin and St. James’s Hospital have demonstrated that dexamethasone, a commonly prescribed anti-inflammatory steroid, reduces harmful inflammation triggered by Mycobacterium avium without weakening the ability of human immune cells to control the infection, according to a study published in the Journal of Infectious Diseases. Understanding Nontuberculous Mycobacterial Disease and Treatment Challenges … Read more

How Early-Life Stress Rewires the Brain for Future Sensitivity

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New research published in the journal Neuron identifies a biological mechanism linking childhood adversity to lifelong stress hypersensitivity. By studying mouse models, scientists discovered that early-life stress (ELS) triggers epigenetic changes—specifically the enrichment of the H3K4me1 histone mark and the enzyme SETD7—within the brain’s ventral tegmental area (VTA), effectively priming dopamine neurons to overreact to … Read more

Study Links Delayed Ewing Sarcoma Growth to Reduced Trk and IGF1R Markers

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According to a study published on August 7, 2026, in Volume 17 of Oncotarget, treatment with the multi-kinase inhibitor K252a transiently delayed the growth of SK-ES-1 Ewing sarcoma tumor xenografts in immunodeficient mice. Led by researchers at the Federal University of Rio Grande do Sul and INCT BioOncoPed in Brazil, the team found that the … Read more

Natural Hormone Suppresses Liver Inflammation via Brain-Gut Pathway

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According to researchers at McMaster University, the naturally occurring hormone GDF15 protects the liver from inflammation and slows the progression of scarring through a brain-to-liver signaling pathway independent of weight loss. Published in Cell Metabolism, the findings challenge longstanding assumptions about the hormone, which is best known for suppressing appetite and promoting weight loss. Understanding … Read more

Nanomaterials: A New Frontier in Cancer Immunotherapy

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Researchers at Nankai University have developed a framework for integrated nanomaterials designed to overcome the physiological and immune-based barriers that frequently limit the effectiveness of cancer immunotherapy. Published April 24, 2026, in the Chinese Journal of Polymer Science, the study outlines how coordinated nanomaterial design can improve drug delivery, antigen presentation, and tumor microenvironment reprogramming … Read more

How Fruit Fly Gut Cells Track Hunger via Cell Viscosity

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According to researchers led by Sa Kan Yoo at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan, gut cell turnover in fruit flies is governed by the volume and viscosity of food rather than specific nutrient signaling pathways. Published in the Proceedings of the National Academy of Sciences, this discovery challenges traditional nutrient … Read more

How Brain Cells Coordinate Movement Planning

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Researchers at the University of Freiburg’s BrainLinks-BrainTools research centre have identified how neurons in the premotor and primary motor cortices coordinate movement planning and execution, according to a study published in Cell Reports. The findings reveal that premotor neurons communicate with both inhibitory and excitatory populations in the primary motor cortex during planning, a mechanism … Read more

Targetable MYH9 Gene: Cancer Progression and Genetic Disorders

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Emami and colleagues, the MYH9 gene is emerging as a central player in both cancer biology and inherited genetic conditions, offering fresh perspectives on precision medicine and targeted therapeutics. MYH9 Gene Structure and Core Cellular Functions The MYH9 gene dictates the production of non-muscle myosin IIA, known structurally and functionally as NMIIA. Did you know? … Read more

FOXA2’s Role in Glucose Regulation: New Review Highlights

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FOXA2 serves as a master transcription factor that coordinates pancreatic development, maintains islet cell identity, and regulates systemic glucose homeostasis, according to a review published in the journal Genes & Diseases (DOI: 10.1016/j.gendis.2025.101972). By orchestrating gene networks from early organogenesis into adulthood, FOXA2 ensures the functional integrity of insulin-producing β-cells and glucagon-secreting α-cells, providing a … Read more

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