New Cancer Target Boosts Immune System Attack

Researchers at the University of Illinois Chicago have identified a molecular switch, the ion channel protein KCNMB1, that regulates cancer cell stiffness. By activating this pathway, scientists can make metastatic cells more rigid, rendering them vulnerable to destruction by the immune system, according to a study published in the journal Developmental Cell. The Physics of … Read more

Genetic Cause of Severe Childhood Lung Disease Identified

Researchers have identified a novel genetic disorder caused by biallelic loss-of-function variants in the TMEM63B gene, according to a report published in the American Journal of Human Genetics. This condition manifests as severe childhood interstitial lung disease, distinct from previously identified neurological symptoms linked to different mutations in the same gene. The discovery, facilitated by … Read more