Metabolism

Iodine and Immunity: How Balance Affects Your Immune System

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According to a narrative review published in the journal Nutrients by researchers at the University of Guelph and ImmunoCeutica Inc., iodine intake follows a narrow U-shaped relationship that dictates how the micronutrient influences immune defenses across humans and domesticated mammals. While adequate intake supports leukocyte metabolism and thyroid-driven immunity, both chronic deficiency and sustained excess … Read more

5 Epigenetic Clocks: Shared and Distinct Aging Signals

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Epigenetic clocks—tools designed to measure biological age through DNA methylation—capture distinct, non-overlapping biological processes rather than a single universal aging mechanism. According to a study published in npj Aging, researchers have developed Transcriptomic Aging Gene Scores (TAGS) to better interpret these clocks, showing that gene expression patterns often predict health outcomes like mortality and frailty … Read more

Chronotype and Liver Health: No Significant Link Found

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A recent cross-sectional study published in the journal Nutrients found no statistically significant link between an individual’s chronotype—their natural preference for morning or evening activity—and the presence of liver fat or fibrosis in adults with overweight or obesity. Researchers at the National Institute of Gastroenterology in Italy assessed 119 medication-naïve participants using the Morningness–Eveningness Questionnaire … Read more

Lipid Droplet Accumulation: A Universal Hallmark of Senescent Cells

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Senescent cells—damaged cells that stop dividing but remain metabolically active—accumulate lipid droplets as a hallmark of their aging state, according to a study published July 1, 2026, in the journal Aging. Researchers led by Noa Rachmian-Cooper and Valery Krizhanovsky at the Weizmann Institute of Science found that these lipid deposits are linked to chronic inflammation … Read more

Evening Chronotype Linked to Later Eating and Higher Body Fat

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Healthy women with an evening chronotype—individuals who naturally prefer later sleep and meal times—show higher body fat percentages and less favorable metabolic markers compared to those with morning or intermediate preferences, according to a study published in Frontiers in Nutrition. Research from the PROMISE study indicates that meal timing, particularly the consumption of energy late … Read more

Bile acid buildup linked to aggressive breast cancer progression

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Research from the University of Virginia (UVA) Comprehensive Cancer Center indicates that a buildup of bile acids, triggered by an unhealthy gut microbiome, can drive hormone receptor-positive (HR+) breast cancer to metastasize to other organs, particularly the lungs. According to Melanie Rutkowski, PhD, this mechanism suggests that FDA-approved bile acid sequestrants or microbiome replenishment could … Read more

Lactoferrin yogurt helps preserve iron stores in women with gestational diabetes

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Lactoferrin-fortified yogurt maintains ferritin levels in pregnant women with gestational diabetes mellitus (GDM) without causing iron overload, according to a randomized trial published in npj Science of Food. The study found that 100 mg of bovine lactoferrin per serving helped stabilize iron stores in women with reduced ferritin, offering a well-tolerated alternative to relying solely … Read more

Gut-Friendly Diet Linked to Lower Heart Disease Risk

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Adults with coronary heart disease (CHD) who follow diets supporting gut microbiota health may face a lower risk of all-cause mortality, according to a retrospective cohort analysis published in the journal Medicine. Researchers using NHANES data (2005–2018) found that participants with the highest Dietary Index for Gut Microbiota (DI-GM) scores had significantly lower death rates … Read more

Blocking ‘Mitch’ Protein Prevents Obesity in Human Cells

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Researchers have identified a protein called MTCH2, or “Mitch,” that regulates how human cells process fat and energy, potentially offering a new target for future obesity treatments. According to a 2025 study published in the EMBO Journal, disabling this protein in human cells forces them to burn more fuel and inhibits the formation of new … Read more

New Breast Cancer Classification Predicts Immunotherapy Success

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Researchers from the Department of Breast Surgery at Fudan University Shanghai Cancer Center and the Department of Oncology at Shanghai Medical College, Fudan University have developed a new classification system for breast cancer based on the cancer-immunity cycle (CIC). Published in Cancer Biology & Medicine in 2026, this framework uses a “CIC score” to categorize … Read more

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