Italy is experiencing a profound demographic shift toward extreme longevity, with the highest concentrations of centenarians and oldest-old populations appearing in the North and Center, according to a study published in the journal Nutrients. Researchers found that while regions like Liguria lead in aging profiles, southern hotspots such as Cilento maintain survival rates comparable to … Read more
Researchers have identified a protein called MTCH2, or “Mitch,” that regulates how human cells process fat and energy, potentially offering a new target for future obesity treatments. According to a 2025 study published in the EMBO Journal, disabling this protein in human cells forces them to burn more fuel and inhibits the formation of new … Read more
The updated ABCs of cardiovascular disease (CVD) prevention framework, published in the American Journal of Preventive Cardiology in 2026, provides a standardized, evidence-based roadmap for clinicians to manage heart health across a patient’s lifespan. By integrating tools like the PREVENT™ risk scoring system and addressing Cardiovascular-Kidney-Metabolic (CKM) syndrome, the framework shifts clinical focus toward early, … Read more
Researchers have identified a new chemical compound, DE19725241, that shows potential in targeting the fat mass and obesity-associated protein (FTO) to treat pancreatic cancer. According to a study published in BIO Integration, the compound demonstrated selective antiproliferative activity in pancreatic cancer cell lines by binding to specific protein sites, offering a potential new scaffold for … Read more
Up to 45 percent of dementia cases could be prevented by addressing modifiable risk factors like physical inactivity and social isolation, according to research from Curtin University. However, a systematic review published in The Lancet Healthy Longevity indicates that traditional public health awareness campaigns often lead to only small improvements in knowledge and limited changes … Read more
Obesity is associated with a distinct molecular program in breast tissue that drives the transition from premalignant lesions to invasive cancer, according to a study published in The American Journal of Pathology. Researchers found that tumors in obese patients rely on stress-adaptive pathways and microenvironment remodeling rather than classical invasive pathways, suggesting that metabolic health … Read more
People with diabetes face significantly slower recovery times and higher rates of long-term complications following COVID-19 infection, according to a study published in Scientific Reports. Research from the University of São Paulo, which tracked 870 hospitalized patients for up to seven months, found that diabetics experienced increased frailty, higher risks of cardiovascular events, and a … Read more
Psychosocial factors like neuroticism and life adversity contribute more to the population burden of depression and anxiety than physiological factors, according to a 13-year study in Translational Psychiatry. Using UK Biobank data, researchers found psychosocial elements account for up to 67% of the depression burden in men and 61% in women. Why do psychosocial factors … Read more
A study published in the journal Scientific Reports reveals that individuals who have contracted SARS-CoV-2 face an increased risk of developing new-onset obstructive sleep apnea (OSA) for up to 4.5 years post-infection. Researchers analyzing electronic medical records from the Montefiore Health System for over 910,000 patients found that COVID-19 infection is independently associated with a … Read more
Exercise interventions during the weight-maintenance phase can help individuals reduce weight regain by an average of 2.81 kg, according to a systematic review and meta-analysis published in Scientific Reports. While physical activity provides a measurable defense against weight regain following dieting or bariatric surgery, current evidence remains inconclusive regarding its ability to significantly reduce total … Read more