A plant-forward, low-protein diet supplemented with precise amounts of the amino acid methionine increases healthspan and reduces frailty in mice, according to a study published in Cell Metabolism by researchers at the University of Southern California (USC). Led by Valter Longo of the USC Leonard Davis School of Gerontology, the team found that balancing specific … Read more
An unidentified 79-year-old patient gained access to the experimental obesity drug retatrutide through the FDA’s compassionate use pathway, according to reports from STAT News and The New Republic. While speculation persists regarding the patient’s identity, federal agencies have declined to confirm if the individual is former President Donald Trump. The drug was requested in April … Read more
Physicians are increasingly prescribing GLP-1 weight-loss medications like Wegovy to children under 12, despite these drugs lacking FDA approval for such young patients. While the medications are currently approved for those 12 and older, pediatric obesity specialists report using them off-label to address severe health complications like Type 2 diabetes and liver dysfunction, though experts … Read more
Pharmaceutical companies are racing to develop drugs that prevent muscle loss during weight reduction, addressing a critical side effect of GLP-1 medications like Ozempic and Zepbound. While current weight-loss drugs often cause patients to lose significant lean mass alongside fat, new candidates—including bimagrumab and Cambrian Biotech’s ATX-304—aim to prioritize metabolic health and muscle preservation, according … Read more
Rapid weight loss from GLP-1 receptor agonists like Ozempic and Wegovy is driving a surge in demand for body-contouring plastic surgery. Surgeons report an increase in procedures to address “Ozempic face,” “Ozempic breast,” and “Ozempic butt,” as patients seek to correct sagging skin and volume loss that occurs when fat cells shrink faster than the … Read more
Obesity and Cancer Risk: How a Landmark Study Rewrote the Rules A new meta-analysis of 1.5 million cancer cases reveals that excess body weight may increase the risk of 19 types of cancer—far more than previously thought. The findings, published in Nature Metabolism, also expose stark regional and gender disparities, challenging global health policies and … Read more
Researchers found that fatigue in healthy adults is linked to specific shifts in gut bacteria and fecal metabolites. According to a study in Scientific Reports, these microbial patterns overlap significantly with those found in ME/CFS and psychiatric disorders, suggesting gut dysbiosis may serve as an early indicator for these conditions. What microbial changes are linked … Read more
Nearly 4 in 10 patients with type 2 diabetes stop their GLP-1 medication within the first year of treatment, according to research presented at the Endocrine Society’s annual meeting, ENDO 2026. While discontinuation rates climb to nearly 6 in 10 by the end of two years, the data reveals a high frequency of patients restarting … Read more
New Clinical Guidelines Aim to Reduce Unnecessary Testing for Precocious Puberty The Endocrine Society has released updated clinical practice guidelines for managing central precocious puberty, emphasizing that not all children showing early signs of development require medical intervention. According to the guidelines, published in The Journal of Clinical Endocrinology & Metabolism, clinicians should prioritize observation … Read more
Nearly half of the world’s population now lives in countries that have implemented national taxes on sugar-sweetened beverages (SSBs), according to a study by the Food is Medicine Institute at Tufts University. Researchers found that 64 countries passed these health-focused levies between 1990 and 2024, a policy shift driven primarily by national burdens of obesity … Read more