Tetanus Surveillance — United States, 2009–2023

by Chief Editor

Tetanus in the US: A Rare But Persistent Threat

Tetanus, often called “lockjaw,” remains a rare but serious infection in the United States, largely thanks to widespread vaccination efforts. However, recent surveillance data reveals nuanced trends that demand continued vigilance. While overall incidence remains low, certain populations are disproportionately affected, and gaps in vaccination coverage persist.

The Declining, Yet Present, Risk

Since the introduction of tetanus toxoid vaccines in the 1940s, cases have plummeted by over 95%. From 2009 to 2023, the incidence was 0.08 cases per million people, a slight decrease compared to the 0.10 cases per million reported between 2001 and 2008. Here’s over 100 times lower than the global incidence estimated in 2019. In 2023, approximately 27 cases were reported nationwide. Despite this success, tetanus hasn’t been eradicated, and sporadic cases continue to occur.

Shifting Demographics of Infection

While tetanus primarily affects adults (86% of cases occur in individuals 18 years and older), the median age of patients is decreasing. During 2009-2023, the median age was 40, compared to 49 years during the 2001-2008 period. This shift may be linked to changing exposure patterns and vaccination rates. Older adults, particularly those over 80 who may not have received the initial vaccine series recommended in 1947, remain at higher risk.

Interestingly, incidence varies by gender. Among those under 65, men are more likely to contract tetanus, potentially due to occupational or recreational exposures. However, among those 80 and older, women experience a higher incidence, possibly related to historical differences in military service (where vaccination was required) or variations in antibody persistence.

The Importance of Complete Vaccination

A significant proportion of tetanus patients have never been vaccinated, or haven’t completed their primary vaccine series. Approximately half of patients with tetanus had no documented history of ever receiving a tetanus toxoid-containing vaccine (TTCV). Even among those who received at least one dose, most hadn’t received a booster in over 10 years. Notably, no deaths were reported among patients with documented receipt of three or more TTCV doses.

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Vaccination coverage rates are high among children (over 92% for DTaP vaccines) and adolescents (over 76% for Tdap boosters). However, adult coverage with a tetanus and diphtheria toxoid vaccine or Tdap is considerably lower, ranging from 57% to 70% between 2013 and 2022.

Treatment and Preventative Measures

Tetanus is a serious illness, with 95% of patients requiring hospitalization. Approximately 1 in 10 individuals who develop tetanus in the US will die, a risk that increases with age (85% of fatalities occur in those 65 and older). Receiving tetanus immune globulin (TIG) appears to significantly reduce the risk of death. no patient who received TIG prophylaxis died.

Prompt wound care and vaccination are crucial. Fewer than half of individuals with tetanus-prone wounds seek medical attention before disease onset. Healthcare providers should ensure patients are up-to-date on their vaccinations and follow treatment guidelines for TIG and TTCV administration.

Neonatal Tetanus: A Rare but Preventable Tragedy

Neonatal tetanus is exceedingly rare in the US, but cases still occur, often linked to home deliveries with insufficient maternal vaccination and non-sterile conditions. Globally, neonatal tetanus remains a significant cause of morbidity and mortality, particularly in low-income countries.

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Frequently Asked Questions

How often should I gain a tetanus booster?
Adults should receive a tetanus booster every 10 years.
What should I do if I get a wound?
Clean the wound thoroughly and see a healthcare provider to determine if a tetanus booster is needed.
Is tetanus contagious?
No, tetanus is not spread from person to person. It’s caused by bacteria entering the body through a wound.
What are the symptoms of tetanus?
Symptoms include a tightening of the jaw muscles (“lockjaw”), muscle spasms, stiffness, and difficulty swallowing.

Pro Tip: Keep a record of your tetanus vaccinations and share it with your healthcare provider.

To learn more about tetanus and vaccination schedules, visit the Centers for Disease Control and Prevention (CDC) website.

Have questions about tetanus or your vaccination status? Share your thoughts in the comments below!

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