Women experiencing heart disease frequently face diagnostic delays because their symptoms are misidentified as anxiety or dismissed by clinicians, according to preliminary data from the IPEC2 study presented at the European Society of Cardiology’s ACNAP Congress 2026. The research, led by the Global Heart Hub, indicates that gender bias and a lack of symptom recognition often result in women receiving treatment only after a life-threatening cardiac event occurs.
Why Are Women’s Heart Symptoms Frequently Misdiagnosed?
Clinical bias remains a primary barrier to early diagnosis for women, according to the IPEC2 study. Women participating in the research reported that healthcare providers often dismissed their concerns by labeling them “too young” or “not the type” to suffer from cardiovascular issues. Professor Vijay Kunadian of Newcastle University notes that these biases, combined with a tendency for women to prioritize family health over their own, lead to significant delays in care.

How Does Symptom Recognition Impact Patient Outcomes?
Current medical guidelines often fail to capture the full spectrum of cardiovascular symptoms experienced by women, according to Global Heart Hub Executive Director Neil Johnson. While clinical focus often remains on symptoms historically associated with men, women frequently report a wider, more varied range of physical indicators. When these are misread as anxiety or non-cardiac conditions, the opportunity for early intervention—such as managing elevated LDL-C—is lost. The study suggests that “thinking heart first” is necessary to improve long-term outcomes and prevent the progression of atherosclerotic cardiovascular disease.
What Are the Next Steps for Cardiovascular Care?
The IPEC2 study recommends a shift toward patient-centered care models that incorporate lived experience into clinical practice. By collecting data across eight countries, including the US, China, Italy, and Canada, researchers aim to influence policy regarding symptom education. The goal is to reduce the “fragmented care” that currently characterizes the patient journey for women with heart valve disease, cardiomyopathy, and high cholesterol. Experts argue that moving toward more equitable diagnostic protocols could significantly reduce the number of women who arrive at a cardiac event before receiving an initial diagnosis.
Pro Tip: Advocate for Your Heart Health
If you feel your symptoms are being dismissed, ask your clinician specifically for a cardiovascular assessment. Keep a log of your symptoms—including duration, intensity, and triggers—to provide a clear, objective record during your consultation.

Frequently Asked Questions
- Why is heart disease often misdiagnosed in women?
Research indicates that gender bias and a reliance on symptom guidelines based primarily on male physiology lead clinicians to mistake cardiac issues for conditions like anxiety. - What is the IPEC2 study?
The Insights & Patient Experiences with Cardiovascular Disease (IPEC2) study is a patient-led initiative by the Global Heart Hub that collects data on women’s experiences with heart conditions across eight countries. - What are the main risk factors for women?
Uncontrolled elevated LDL cholesterol is a primary driver of atherosclerotic cardiovascular disease, which remains the leading cause of death for women worldwide.
Are you interested in learning more about how to advocate for your own health? Explore the full range of resources at Global Heart Hub and subscribe to our newsletter for the latest updates on cardiovascular research and patient advocacy.
