Addison’s Disease: How Skin Darkening Led to a Life-Saving Diagnosis

Hyperpigmentation as a Clinical Red Flag Unexplained skin darkening on the hands, feet, gums, and tongue can serve as the primary diagnostic indicator of Addison’s disease, a rare endocrine disorder. According to a case report published in the journal Skin on June 4, 2026, clinicians identified this specific hyperpigmentation in a 24-year-old patient two years … Read more