Genetic Barcodes Reveal How Chromosomes Recognize Each Other

Repetitive satellite DNA sequences in fruit flies function as chromosome-specific barcodes that help matching chromosome pairs find each other during meiosis, according to research published in Nature Communications. When ETH Zurich scientists Lena Skrutl and Madhav Jagannathan disrupted these satellite DNA patterns on two chromosome pairs simultaneously, pairing errors increased sharply and the DNA-binding protein … Read more