Ketogenic diet mediates intestinal tumorigenesis through lipids not ketones
Dietary patterns directly regulate intestinal stem cells (ISCs), where high-fat intake enhances tumorigenicity and calorie restriction suppresses cancer risk. According to research published in Nature Reviews Gastroenterology & Hepatology (2025) and Nature (2016), high-fat diets increase “stemness” in intestinal progenitors, while ketone bodies like β-hydroxybutyrate can suppress colorectal cancer growth. How High-Fat Diets Trigger Intestinal … Read more