Open Dialogue, a person-centred mental health care model originating in Finland, significantly reduces psychiatric hospital admissions and improves patient quality of life, though it does not impact the time to first relapse, according to a randomised controlled trial led by University College London (UCL) researchers and published in The Lancet Psychiatry. Evaluating the ODDESSI Trial … Read more
Researchers at the Mass General Brigham Neuroscience Institute have discovered that a specific pattern of brain shrinkage visible on MRI scans can help predict how quickly individuals with early-onset Alzheimer’s disease progress from mild cognitive impairment to dementia, according to findings published in the journal Neurology. MRI Brain Atrophy Predicts Early-Onset Alzheimer’s Progression Early-onset Alzheimer’s … Read more
Preply cofounder Kirill Bigai operated without a salary for an entire year to help build the language-learning platform into a $1.2 billion unicorn, according to Fortune. The bootstrapped start-up relied on personal sacrifices and side jobs before raising a $150 million Series D funding round led by WestCap in January, bringing its total funding to … Read more
A biological age score derived from four common blood markers—chronological age, creatinine, blood glucose, and C-reactive protein (CRP)—successfully predicted future cognitive impairment in middle-aged and older adults, according to a study published in Scientific Reports. Researchers found that this “light BioAge” index provides a more nuanced look at cognitive risk than age alone, offering a … Read more
Natural language processing models that analyze the exact words children use when talking about stressful events prove better at predicting future mental health problems than a panel of human experts, according to a study published in Nature Mental Health. Researchers at Stanford’s School of Humanities and Sciences found that evaluating recorded interviews of more than … Read more
Automated AI Evaluation in Clinical Settings: The Human Gap According to a study published in npj Digital Medicine, while AI models offer high internal consistency, they remain insufficient as a total replacement for human oversight in resource-constrained healthcare environments. The Cost-Effectiveness of AI Judging Deploying generative AI for clinical decision support requires rigorous, ongoing validation. … Read more
Researchers have identified a new chemical compound, DE19725241, that shows potential in targeting the fat mass and obesity-associated protein (FTO) to treat pancreatic cancer. According to a study published in BIO Integration, the compound demonstrated selective antiproliferative activity in pancreatic cancer cell lines by binding to specific protein sites, offering a potential new scaffold for … Read more
Researchers at The University of Texas MD Anderson Cancer Center have mapped the spatial architecture of muscle-invasive bladder cancer, identifying how tumor cell states and immune environments interact within specific regions of a tumor. Published in Cancer Discovery, the study reveals that bladder cancer is not a uniform disease, but a complex landscape where luminal … Read more
Problematic social media use (PSMU) is linked to a significant increase in everyday memory failures, according to a recent study published in Frontiers in Psychiatry. Researchers found that young adults who engage in high-frequency social media use report more frequent lapses in both retrospective recall and prospective memory—the ability to remember intended future actions. Data … Read more
A federal judge has ordered the Trump administration to reinstate signage at national parks that was removed under a March 2025 executive order. U.S. District Judge Angel Kelley issued a preliminary injunction in Boston on Friday, requiring the restoration of markers related to climate change, slavery, and Indigenous and LGBTQ+ history before the July Fourth … Read more