How Peripheral Inflammation May Trigger Parkinson’s Disease

Systemic inflammation originating in the body’s periphery—rather than the brain itself—may be a primary driver of Parkinson’s disease, according to research published in Cell Reports. Scientists suggest that the LRRK2 mutation, common in Parkinson’s patients, triggers a cycle where cellular waste is packaged into extracellular vesicles (EVs) that cross the blood-brain barrier, effectively transporting inflammatory … Read more