Preclinical

African Bundibugyo Ebolavirus Vaccine Advances to Clinical Trials

by

Minapharm Group will receive up to $16.5 million from the Coalition for Epidemic Preparedness Innovations to develop a Bundibugyo ebolavirus vaccine candidate, addressing an escalating outbreak in the Democratic Republic of the Congo, according to a joint announcement from the organizations. CEPI Funding Advances Minapharm Vaccine Candidate for DRC Outbreak Leading African biopharmaceutical company Minapharm … Read more

HRT and Dementia Risk: The Importance of Timing and Menopause Type

by

Recent findings from a large UK Biobank analysis published in the journal Alzheimer’s & Dementia indicate that hormone replacement therapy use is associated with a modest 10% reduction in all-cause dementia risk among postmenopausal women, though the effect varies significantly depending on menopause type, estrogen exposure duration, and the timing of treatment initiation. UK Biobank … Read more

Mosquito Bite Vaccine: A New Breakthrough in Immunity

by

Researchers at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, have developed a new vaccination approach that uses antimalarial drug compounds to transform mosquito bites from a source of deadly infection into natural immune boosters, according to a study published in Science. Targeting the Late Liver Stage to Build Durable Immunity The preclinical … Read more

UH College of Pharmacy Secures Funding for Three Major Health Studies

by

University of Houston College of Pharmacy researchers secured more than $1 million in new funding to tackle three distinct healthcare challenges, including sepsis, Alzheimer’s disease, and sickle cell-related depression, according to institutional announcements. The grants back projects aimed at developing new drug delivery systems, artificial intelligence tools, and specialized diagnostic screeners to improve patient outcomes. … Read more

Advancing Precision Oncology with New Tumor Organoids

by

Patient-derived tumor organoids are emerging as high-fidelity preclinical models for precision oncology, offering a way to test cancer treatments on three-dimensional cell clusters that mirror a patient’s specific disease. Recent research led by investigators at Weill Cornell Medicine demonstrates that these “avatars” can reliably predict treatment sensitivity, potentially expanding the pool of patients eligible for … Read more

Unlocking the Role of the Immune System in Oral Precancerous Lesions

by

Breakthrough in Oral Cancer Research: New Immune Pathway Could Revolutionize Early Intervention Researchers at The University of Texas MD Anderson Cancer Center have uncovered a critical immune pathway linked to the progression of oral precancerous lesions into head and neck squamous cell carcinoma, offering a potential roadmap for early intervention. The findings, published in *Cancer … Read more

New Therapy Harnesses Cells’ Waste Removal to Target Multiple Myeloma

by

Researchers at VCU Massey Comprehensive Cancer Center have developed an experimental molecule called an autophagy-targeting chimera (AUTAC) that dismantles the MCL1 survival protein to kill multiple myeloma cells. According to a study published in Cell Death & Disease, this targeted protein degrader works with existing proteasome inhibitors to reduce cancer cell viability by 50% within … Read more

BCG Vaccine May Alter Human Brain Immunity

by

The Bacillus Calmette-Guérin (BCG) vaccine, typically used to prevent tuberculosis, may remodel the brain’s immune environment to potentially lower Alzheimer’s disease risk, according to research published in Communications Medicine. A year-long study led by Mass General Brigham investigators found the vaccine increased immune cell responsiveness and altered Alzheimer’s-related biomarkers in older adults without pre-existing pathology. … Read more

Prime-and-Pull Vaccine Effectively Prevents Genital Herpes

by

Researchers at the Yale School of Medicine have developed a two-part vaccination strategy that successfully prevented genital herpes infection in preclinical models. Published June 19 in Science Immunology, the study uses “prime and pull” technology—an initial intramuscular injection combined with localized nanoparticle delivery—to trigger a robust immune response at the vaginal lining, a feat traditional … Read more

New Geroscience Initiative to Accelerate Anti-Aging Therapies

by

The Albert Einstein College of Medicine has launched the Batia and Idan Ofer program for Validation of Interventions Targeting Aging and Longevity (BIO-VITAL), a specialized initiative designed to accelerate the development of pharmaceutical therapies that address the biological mechanisms of aging. By providing biotechnology firms access to proprietary research models and human longevity data, the … Read more

© 2026 Newsy Today. All rights reserved.


For contact, advertising, copyright, issues email: office@newsy-today.com

For contact, advertising, copyright, issues email: office@newsy-today.com