A large-scale observational study involving 340,924 adults suggests that wine consumption may be linked to a lower risk of death compared to beer or spirits. Presented at the American College of Cardiology’s Annual Scientific Session, the research found that while heavy drinking increases mortality risk regardless of beverage type, moderate wine intake was associated with a 21% lower risk of cardiovascular death compared to non-drinkers, according to data from the UK Biobank.
Mortality Risks Linked to Alcohol Intake Levels
Researchers analyzed health outcomes for participants enrolled in the UK Biobank between 2006 and 2022, following them for an average of over 13 years. The findings establish a clear threshold where alcohol consumption becomes detrimental. Compared to individuals who never or only occasionally consumed alcohol, those classified as high-consumption participants showed a 24% increased likelihood of dying from any cause, a 36% greater chance of mortality from cancer, and a 14% higher risk of death associated with heart disease.

The study defined heavy consumption as daily consumption of more than 40 g for men and 20 g for women. Approximately 14 grams of pure alcohol can be found in a 12-ounce can of beer, a 5-ounce glass of wine, and a 1.5-ounce shot of spirits as a baseline comparison.
The Beverage-Specific Divide in Cardiovascular Health
The research highlights a significant contrast in health outcomes at lower levels of alcohol intake. While moderate wine consumption was linked to a 21% reduction in cardiovascular death risk, the opposite was true for other types of alcohol. According to the study authors, even low intake of beer, cider, or spirits was associated with a 9% higher risk of cardiovascular death compared to those who abstained or drank only occasionally.
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Researchers suggest that the potential benefits associated with wine may stem from polyphenols and antioxidants. Additionally, wine drinkers in the study tended to consume alcohol with meals and report higher-quality diets compared to those who primarily drank beer or spirits.
Limitations and Expert Cautions
Despite the findings, experts emphasize that the study does not provide a mandate for daily drinking. Jessica Steinman, LMFT, CSAT, chief clinical officer for Los Angeles-based No Matter What Recovery, noted that the results should not be interpreted as a blanket endorsement of alcohol use, specifically warning that individuals struggling with substance use should avoid alcohol entirely.
The study authors acknowledged several limitations that prevent a direct causal link. Because the research is observational, it cannot prove that wine directly causes lower mortality. Furthermore, alcohol intake was self-reported only at the start of the study, leaving potential changes in drinking habits over the 13-year period unrecorded. Pointing out that these beverage-specific variations require further exploration through randomized clinical trials, Julian Braithwaite—president and CEO of the London-based International Alliance for Responsible Drinking, an organization supported by prominent beer, wine, and spirits manufacturers—remarked that the data remains complex to interpret conclusively.
Frequently Asked Questions
Does this study prove that drinking wine is good for your heart?
No. The study is observational and cannot establish cause and effect. While there is an association between moderate wine consumption and lower cardiovascular risk, researchers emphasize that this may be influenced by lifestyle factors, such as diet and how the alcohol is consumed.

What is considered “moderate” drinking in this research?
Moderate consumption was defined as 20 g to 40 g for men and 10 g to 20 g for women. This is roughly equivalent to 1.5 to three standard drinks for men and 1.5 drinks for women.
Are there risks associated with even low levels of alcohol?
Yes. According to the study, low levels of beer, cider, and spirits were associated with a 9% higher risk of cardiovascular death compared to those who do not drink.
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