Calocurb, a New Zealand-based company, has announced findings from a new clinical study published in the US medical journal Obesity Pillars. According to the brand, the research demonstrates that its 100% natural GLP-1 activator effectively promotes weight loss while preserving muscle mass during six months of consistent use paired with a healthy diet and exercise.
Clinical Study Results on Natural GLP-1 and Weight Loss
In its fourth human clinical study, Calocurb users achieved an average weight loss of 8.3 lbs (3.77 kg) over six months, compared to just 0.88 lbs (0.4 kg) in the placebo group, according to company data. Participants using the supplement experienced over 6.5 times a greater reduction in body fat than those taking the placebo. Specifically, the average body fat loss reached 9.9 lbs (4.49 kg) for the Calocurb group, versus 1.5 lbs (0.68 kg) for the placebo group.
Did you know? According to the published trial data, Calocurb users lost an average of 5 square inches (32.5 cm2) of visceral fat, compared to 1.4 square inches (9.1 cm2) in the placebo group—representing a 3.5x greater reduction.
How Amarasate® Activates Natural Satiety Hormones
Unlike prescription GLP-1 medications, Calocurb relies on a patented bitter hops extract known as Amarasate®. This extract originated from an extensive research program funded by the New Zealand government. According to company disclosures, the ingredient works by stimulating three of the body’s natural satiety hormones—GLP-1, CCK, and PYY. It achieves this by activating bitter taste receptors located in the L-cells of the gastrointestinal tract, which helps curb hunger, cravings, and overall calorie intake.
“The new clinical data proves not only Calocurb’s contribution to weight loss overall, but also muscle preservation, which is groundbreaking in the crowded space of GLP-1s and other weight reduction options,” said Sarah Kennedy, Founder and CEO of Calocurb, regarding the publication in Obesity Pillars. Kennedy noted that after years of research, the brand now has independent clinical data confirming the supplement’s effectiveness in improving body composition naturally.
Future Implications for Natural Weight Management
For over a decade, Calocurb has conducted clinical research into Amarasate® to continue bringing natural weight management options for consumers interested in GLP-1 solutions. The company states that the latest findings open new doors for individuals pursuing weight management through science-backed, natural wellness tools designed for patients, practitioners, and consumers alike.
Frequently Asked Questions
How does Calocurb differ from prescription GLP-1 medications?
Prescription GLP-1 medications are drugs, whereas Calocurb is a 100% natural supplement derived from a patented bitter hops extract called Amarasate®. It stimulates the body’s own satiety hormones by activating bitter receptors in the gut.
What was the average weight loss in the latest clinical study?
According to the study published in Obesity Pillars, users saw an average weight loss of 8.3 lbs (3.77 kg) after six months of consistent use alongside a real-world diet and exercise plan.
Did participants lose muscle mass during the trial?
No, the clinical study demonstrated that users experienced significant reductions in body fat and visceral fat with no loss in muscle mass.
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