How Platinum Chemotherapy Accelerates Cellular Aging in Children

Platinum-based chemotherapy drugs like cisplatin and carboplatin cause significant, hidden DNA damage in healthy tissues and can age a child’s cells by decades in a short period, according to a study published in Science by researchers at the Wellcome Sanger Institute, the University of Cambridge, the Francis Crick Institute, and King’s College London. While these … Read more

Genetic Newborn Screening for Early-Onset Cancer Risk

Genomic newborn screening using heel-stick blood spots can identify infants at high risk for early-onset cancers before symptoms appear, according to a Nature Communications study led by researchers from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Mass General Brigham, and collaborators. Analyzing archived samples from 1,948 children in Michigan who developed solid or central nervous … Read more