APOE Genotype Enhances P-Tau217 Prediction of Cognitive Impairment Risk

Higher plasma phosphorylated tau 217 concentrations are linked to a significantly greater risk of cognitive impairment, particularly among adults carrying the apolipoprotein E epsilon-4 allele, according to a pooled analysis published in The Lancet Neurology. Researchers evaluated participant-level data from seven multiethnic prospective cohort studies to understand how genetic background alters the prognostic meaning of … Read more