Researchers at the Sant Pau Research Institute in Barcelona have identified early microscopic white matter abnormalities in Alzheimer’s disease patients using a specialized neuroimaging metric called peak width of skeletonized mean diffusivity, or PSMD. According to a study published in the journal Alzheimer’s & Dementia, this advanced diffusion magnetic resonance imaging tool detects subtle structural … Read more
Hallucinations and delusions appearing for the first time in midlife or later are frequently categorized as psychiatric symptoms of unclear biological origin, but new research published in Molecular Psychiatry reveals they may be linked to dementia-related brain changes. According to the National Institutes for Quantum Science and Technology, about 65 percent of patients who develop … Read more
Artificial intelligence can now generate detailed maps highlighting differences in how distinct parts of the brain age, according to a study published in the journal Proceedings of the National Academy of Sciences. Developed by University of Southern California researchers, the deep learning model analyzes magnetic resonance imaging (MRI) scans from nearly 15,000 individuals to map … Read more
Researchers at Carnegie Mellon University, the University of Pittsburgh, and the University of Washington have mapped how 3D genome architecture differs in brain cells affected by Alzheimer’s disease. According to a study published in Science, the research team linked genome folding to gene activity and brain tissue organization using single-cell technology, spatial mapping, and a … Read more
Researchers have identified the protein Arc as a critical vehicle that transports toxic Tau protein between neurons, potentially driving the progression of Alzheimer’s disease. According to a study published in Cell by investigators at University of Utah Health and Washington University in St. Louis, interrupting this intercellular transport mechanism could offer a new therapeutic strategy … Read more
Moderate daily movement—roughly 3,000 steps—may significantly slow cognitive decline and protect brain health in older adults, according to research published in Nature in November 2025. While the activity does not clear amyloid plaques often targeted by Alzheimer’s medications, it appears to inhibit the accumulation of tau proteins, which are more directly linked to memory loss … Read more
Senescent cells—damaged cells that stop dividing but remain metabolically active—accumulate lipid droplets as a hallmark of their aging state, according to a study published July 1, 2026, in the journal Aging. Researchers led by Noa Rachmian-Cooper and Valery Krizhanovsky at the Weizmann Institute of Science found that these lipid deposits are linked to chronic inflammation … Read more
Up to 45% of global dementia risk could be prevented or delayed by addressing modifiable risk factors across a person’s lifespan, according to updated guidance released by the World Health Organization (WHO) on 15 July 2026. By targeting lifestyle habits and chronic health conditions, the WHO aims to reduce the burden on the more than … Read more
Regularly sleeping nine to 10 hours or more per night is linked to higher levels of p-tau181, a blood-based protein marker for Alzheimer’s disease, according to a study from UT Health San Antonio. Researchers found that the association becomes most pronounced beyond 10 hours of sleep, suggesting long sleep may be an early indicator of … Read more
Individuals with early-onset dementia—defined as a diagnosis occurring before age 65—experience a significant, accelerating decline in work productivity up to 15 years before receiving a clinical diagnosis. Research published in the journal Neurology on July 8, 2026, reveals that these patients face an average productivity loss of 74,577 Euros (approximately $86,000 USD) compared to their … Read more